Results 131 to 140 of about 5,412 (286)

Ordered assembly of Cas12a for better performance of CRISPR/Cas system with application to the diagnosis of dental caries

Interdisciplinary Medicine, EarlyView.
Here, we present a tetrahedral DNA framework (TDF)‐mediated Cas12a ordered assembly strategy. TDFs arrange CRISPR/Cas12a into ordered structures controllably, enhancing catalytic efficiency through localized Cas12a hotspots while maintaining spatial intervals to facilitate substrate diffusion.
Yining Zhao, Panpan Qiao, Yujing Zeng, Murtaza Sayed, Qin Mi, Juan Zhang, Genxi Li   +6 more
wiley   +1 more source

Study on the Calculation Method of Soil-Nailing for High Soil Slope Based on the Logarithmic Spiral Slippery Fracture

, 2011
This paper introduces a new failure mode pattern of soil slope – the logarithmic spiral slippery fracture. A mathematical model for the logarithmic spiral slippery fracture is established, taking the anti-shear function of the soil-nailing into ...
Xiao Min Liu, Meng Yang
core   +1 more source

Colonic Barrier Dysfunction and Inflammation Induced by Nano‐/Micro‐Plastics Fibers in Mice via the FAK/NF‐κB/iNOS and TLR4/NF‐κB/iNOS Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT As emerging environmental contaminants, nano‐ and micro‐plastics (NMPs) have drawn increasing research attention due to potential hazards to organisms. Particle shape is a key factor influencing the toxic effects of NMPs, and NMPs of different shapes cause varying degrees of tissue damage. We investigated the specific mechanisms of polystyrene
Yuting Li, Shibo Bao, Puyang Huang, Jiahui Wang, Hongfeng Li, Yahong Liu, Kai Wang, Jianjun Du, Lingjun Yan, Guowei Pan, Wei Sun   +10 more
wiley   +1 more source

Maximum Entropy (Most Likely) Double Helical and Double Logarithmic Spiral Trajectories in Space-Time. [PDF]

Sci Rep, 2019
Parker MC, Jeynes C.
europepmc   +1 more source

A two-channel monopulse reflector antenna system with a multimode logarithmic spiral feed

, 1966
Two-channel monopulse reflector antenna system with multimode logarithmic spiral ...
Lantz, P. A.
core  

Analysis of Bearing Capacity for Logarithmic Spiral Slip Surfaces [PDF]

, 1988
In this paper, a conventional and practically useful analytical method of bearing capacity is presented, assuming that slip lines in the foundation are composed of a single logarithmic spiral curve.
成田, 国朝, 山口, 柏樹
core  

Construction of a Non‐Invasive Predictive Model Based on PIVKA‐II Combined With MRI Imaging Features for Evaluating Microvascular Invasion in Hepatocellular Carcinoma

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study developed a non‐invasive model using PIVKA‐II and MRI features to predict microvascular invasion in hepatocellular carcinoma, providing a reliable tool for early risk assessment and personalized treatment planning. The study included 98 patients with pathologically confirmed HCC (Child‐Pugh A, BCLC stage A), comprising 43 MVI ...
Di Gao, Rui‐Qi Jin, Hong‐Wei Wang
wiley   +1 more source

TRIM Expression and Its Association With Disease Activity in Systemic Lupus Erythematosus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Systemic lupus erythematosus (SLE) is a chronic autoimmune disease with diverse manifestations, including rash, arthritis, and nephritis. Although autoantibodies are a key feature of SLE, their levels often poorly reflect disease severity, suggesting the involvement of additional contributing factors.
Ling‐Ying Lu, Ling‐Jung Yen, Hui‐Ling Hsia, Zi‐Xeng Weng, Chi‐Hsiang Chung, Paul Wei‐Che Hsu, Chih‐Wei Chiu, Wu‐Chien Chien, Tsung‐Hsien Chang   +8 more
wiley   +1 more source

An improved black hole algorithm designed for K-means clustering method

Complex & Intelligent Systems
Data clustering has attracted the interest of scholars in many fields. In recent years, using heuristic algorithms to solve data clustering problems has gradually become a tendency.
Chenyang Gao, Xin Yong, Yue-lin Gao, Teng Li   +3 more
doaj   +1 more source

Fibonacci-Inspired Spiral Quilts

This article provides insight into the mathematics and designs of quilts inspired by Fibonacci and logarithmic spirals. We introduce the history and development of the Fibonacci number sequence and how to hand-draw a Fibonacci spiral. Further, we explain
Collins, SK, Radcliffe, David, Offenholley, Kathleen   +2 more
core   +1 more source