Results 131 to 140 of about 12,458 (247)

Genetic risk factors in Finnish patients with Fuchs endothelial corneal dystrophy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To study the genetic risk factors of Fuchs endothelial corneal dystrophy (FECD) in the Finnish population using hospital‐based and large biobank cohorts. Methods We genotyped a cohort of 107 Finnish patients with FECD for the primary associated genetic risk factor, the TCF4 (CTG)>50 expansion, and studied their clinical phenotype.
Inka‐Tuulevi Vähämäki   +10 more
wiley   +1 more source

The amino terminal domain of the human α7 nicotinic acetylcholine receptor subunit leads to the functional expression of human/insect receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Human α7 receptors have been characterised in terms of pharmacological properties. Insertion of the N‐terminal domain of the human α7 subunit leads to honeybee and cockroach chimeric receptors activated by ACh and inhibited by α‐Bgt. Insertion of the human cys‐loop leads to cockroach chimeric receptors modulated by PNU.
Alison Cartereau   +9 more
wiley   +1 more source

ITGA5 as a Dual Regulator of Epithelial‐Mesenchymal Transition and Epithelial Cell Anoikis Resistance: Functional Validation and Drug Prediction

open access: yesCell Proliferation, EarlyView.
Proteomics and functional validation reveal ITGA5 as a dual promoter of epithelial‐mesenchymal transition and anoikis resistance in human bronchial epithelium: targeting ITGA5 represents a novel therapeutic strategy for asthma airway remodelling. ABSTRACT Airway remodelling is a major contributor to persistent airflow limitation and irreversible lung ...
Ting Wang   +10 more
wiley   +1 more source

Logarithmic Helical Design for Reversed Magnetic Field in Magnetoelastic Soft Matters with Giant Current Outputs. [PDF]

open access: yesAdv Sci (Weinh)
Chen X   +11 more
europepmc   +1 more source

Vernalization regulatory network identifies potential novel functions for genes in the HvVRN2 locus

open access: yesNew Phytologist, EarlyView.
Summary Flowering is controlled by environmental and genetic factors. Vernalization requirement in barley (Hordeum vulgare L.) is determined by the allele in HvVRN1 and the presence of locus HvVRN2, which consists of two zinc‐finger and CONSTANS‐like domains (ZCCT) genes: HvVRN2a and HvVRN2b.
Francesc Montardit‐Tarda   +6 more
wiley   +1 more source

The cyanobacterial protein VIPP1 forms ESCRT-III-like structures on lipid bilayers. [PDF]

open access: yesNat Struct Mol Biol
Pan S   +5 more
europepmc   +1 more source

NPF2 is involved in intracellular pH regulation and ion balance in the diatom Phaeodactylum tricornutum

open access: yesNew Phytologist, EarlyView.
Summary Cellular ion and pH homeostasis are crucial factors affecting and regulating metabolic reactions, protein stability, signalling and transport mechanisms. To balance intracellular ion concentrations, organisms need to constantly sense and respond to both the extracellular environment and cell compartments' requests.
Anna Santin   +15 more
wiley   +1 more source

Home - About - Disclaimer - Privacy