Results 61 to 70 of about 1,034 (248)
Enhanced Intracellular Stability and Translation Efficiency of mRNA Drugs by a 2‐arm mRNA Platform
Advanced Science, EarlyView.We constructed a 2‐arm mRNA, characterized by a unique topology formed through the dimerization of two mRNA 3’ tails. The 2‐arm mRNA improves 3’ tail stability and resistance to nuclease degradation, resulting in an intracellular half‐life of up to 65 h. This method substantially enhances the translation capacity of mRNA drugs.
Xucong Teng +5 more
wiley +1 more source
A New View of the Spiral Structure of the Northern Outer Milky Way in Carbon Monoxide
The Astrophysical Journal LettersBased on 32,162 molecular clouds from the Milky Way Imaging Scroll Painting project, we obtain new face-on molecular gas maps of the northern outer Galaxy. The total molecular gas surface density map reveals three segments of spirals, extending 16–43 kpc
Yan Sun +15 more
doaj +1 more source
Advanced Science, EarlyView.A catalytic allosteric DNAzyme assay (SMART) is developed by engineering DNAzyme into a unimolecular biosensor, enabling highly sensitive and multiplex detection of small molecules and nucleic acids. SMART enables extraction‐free, one‐pot, one‐step, isothermal, and cost‐effective detection of biological markers, achieving >95% accuracy for rapid ...
Yanzhe Shen +12 more
wiley +1 more source
New Journal of PhysicsWe introduce jerky chiral active Brownian particles (ABP), a generalization of conventional chiral ABPs subjected to jerk, the time derivative of acceleration, and analytically derive their mean displacement and mean squared displacement.
Stephy Jose, Hartmut Löwen
doaj +1 more source
Advanced Science, EarlyView.A novel near‐infrared‐II fluorescent imaging capsule endoscope that detects specific fluorescence signals above 900 nm enables highly sensitive, targeted imaging of gastrointestinal cancer tissue. This wirelessly powered and magnetically controlled “smart pill” achieves high sensitivity and deep tissue penetration, allowing precise, non‐invasive ...
Weicheng Wang +10 more
wiley +1 more source
Fitting an Origin-Displaced Logarithmic Spiral to Empirical Data by Differential Evolution Method of Global Optimization [PDF]
, 2006 Logarithmic spirals are abundantly observed in nature. Gastropods (such as nautilus, cowie, grove snail, thatcher, etc.) in the mollusca phylum have spiral shells, mostly exhibiting logarithmic spirals vividly. Spider webs show a similar pattern. The low-
S. K. Mishra, Mishra, SK
core +1 more source
Advanced Science, EarlyView.Monolithically integrated Sb2S3 on industry‐compatible textured silicon for tandem photoelectrochemical hydrogen evolution coupled with iodide oxidation. ABSTRACT Solar‐driven photoelectrochemical (PEC) production of chemical fuels such as hydrogen is a viable solution to address climate neutrality objectives.
Jihong Min +13 more
wiley +1 more source
Water‐Mediated Phosphoryl Wires Stabilize Pathological Tau Fibrils
Angewandte Chemie, EarlyView.Extended 1D phosphoryl “wires” stabilize in‐register amyloid tau fibrils, as demonstrated by multiple‐quantum spin‐counting NMR, TEM, and MD simulations, using fibrils of tau peptide jR2R3‐P301L (tau295–313) with phosphorylation at S305 or Y310. ABSTRACT Hyperphosphorylation of tau is a hallmark of tauopathies, with specific phosphorylation sites ...
Lokeswara Rao Potnuru +8 more
wiley +2 more sources
, 2016 trigonometric functions, hyperbolas, parabolas, cardioids,lemniscates, logarithmic spiralSinusoidal spirals are given by the equation r^s=a^s(cos(s.t)), where s is rational.
Morris, Rob
core +1 more source
On the Determination and Use of Principal Lines
Engineering Transactions, 1977 Assuming plane strain for Huber-Mises yield condition (for a Coulomb-Tresca one, both plane strain and stress are admitted) of incompressible homogeneous isotropic ideal plastic medium, basic relation of principal lines (of curvatures and their ...
M. Rogoziński
doaj