Results 71 to 80 of about 12,450 (260)
Advanced Science, EarlyView.This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing +10 more
wiley +1 more source
New Journal of PhysicsWe introduce jerky chiral active Brownian particles (ABP), a generalization of conventional chiral ABPs subjected to jerk, the time derivative of acceleration, and analytically derive their mean displacement and mean squared displacement.
Stephy Jose, Hartmut Löwen
doaj +1 more source
Advanced Science, EarlyView.Dimethylsulfoniopropionate (DMSP) is a major marine organosulfur compound central to climate‐relevant dimethyl sulfide (DMS) production. In Halomonas sp. D47, DMSP catabolism is revealed to be coordinated by two transcriptional regulators, AcuR and AcuZ, which control gene expression by sensing DMSP and its metabolites.
Li‐Yuan Zheng +16 more
wiley +1 more source
Lipid‐Facilitated Opening of the ADAM10 Sheddase Revealed by Enhanced Sampling Simulations
Advanced Science, EarlyView.Phosphatidylserine acts as a lipid trigger to enhance activation of the sheddase ADAM10. By integrating fluorescence spectroscopy assays with enhanced sampling molecular dynamics simulations, this study shows that phosphatidylserine promotes ADAM10 catalytic activity along with expansion of its extracellular domains, enhancing accessibility to scaffold
Adrien Schahl +7 more
wiley +1 more source
On the Determination and Use of Principal Lines
Engineering Transactions, 1977 Assuming plane strain for Huber-Mises yield condition (for a Coulomb-Tresca one, both plane strain and stress are admitted) of incompressible homogeneous isotropic ideal plastic medium, basic relation of principal lines (of curvatures and their ...
M. Rogoziński
doaj
Spirality: A Novel Way to Measure Spiral Arm Pitch Angle
, 2016 We present the MATLAB code Spirality, a novel method for measuring spiral arm pitch angles by fitting galaxy images to spiral templates of known pitch. Computation time is typically on the order of 2 minutes per galaxy, assuming at least 8 GB of working ...
Boe, Benjamin +8 more
core
, 2013 We propose a new, more realistic, description of the perturbed gravitational potential of spiral galaxies, with spiral arms having Gaussian-shaped groove profiles.
Barros, D. A. +3 more
core +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Advanced Science, EarlyView.Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
Dynamics of Gaseous Disks in a Non-axisymmetric Dark Halo
, 2011 The dynamics of a galactic disk in a non-axisymmetric (triaxial) dark halo is studied in detail using high-resolution, numerical, hydrodynamical models. A long-lived, two-armed spiral pattern is generated for a wide range of parameters.
A. Burkert +47 more
core +1 more source