Results 71 to 80 of about 449,073 (289)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Simulation Analysis of Soft Focusing of Azimuth Laterolog Resistivity Imaging LWD Tool

Cejing jishu
When logging while drilling directional lateral instruments work in formations, due to the long length of the drill collar, the surface potential attenuation is severe.
TANG Zhanghong, YANG Zhiliang, CHEN Gang, ZHANG Guoyan, ZHAI Xingyu, SONG Sen   +5 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Application of Multi-Scale Borehole Acoustics Imaging Technology to Fracturing Effects Evaluation

Cejing jishu
Multiple types of waves co-existing in borehole acoustic logging, can provide various insights about the formation, because of their complementary investigation depth and perspectives. Focusing on ever-increasing needs in post-fracturing evaluation, this
SUN Xuekai, YU Chunhao, ZHANG Hao, ZHOU Jufeng, LIU Xianping   +4 more
doaj   +1 more source

Can timber provision from Amazonian production forests be sustainable? [PDF]

, 2019
Around 30 Mm3 of sawlogs are extracted annually by selective logging of natural production forests in Amazonia, Earth's most extensive tropical forest.
Ascarrunz, Nataly, Blanc, Lilian, Carneiro Guedes, Marcelino, Derroire, Géraldine, Descroix, Laurent, d’Oliveira, Marcus Vinicio Neves, Herault, Bruno, Honorio Coronado, Eurídice N., Huth, Andreas, Kanashiro, Milton, Licona, Juan Carlos, Mazzei, Lucas, Peña-Claros, Marielos, Piponiot-Laroche, Camille, Putz, Francis E., Rodney, Ken, Rodrigues de Souza, Cintia, Rutishauser, Ervan, Rödig, Edna, Shenkin, Alexander, Sist, Plinio, Vidal, Edson, West, Thales A.P., Wortel, Verginia   +23 more
core   +4 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Classification Evaluation Method for Complex Reservoirsin Xinglong Structural Belt

Cejing jishu
The reservoir of Linhe formation in the Xinglong tectonic belt of the Hetao basin is controlled by low geothermal temperature and late deep burial, with obvious weak diagenetic characteristics, strong heterogeneity of the reservoir, and complex pore ...
LI Xiaofeng, CAI Jun, XIAO Chengwen, CAI Wenyuan, YU Weigao, FU Shaoqing, GUO Yuqing   +6 more
doaj   +1 more source

Determining Factors Behind the PageRank Log-Log Plot [PDF]

, 2007
We study the relation between PageRank and other parameters of information networks such as in-degree, out-degree, and the fraction of dangling nodes. We model this relation through a stochastic equation inspired by the original definition of PageRank.
Volkovich, Yana, Litvak, Nelly, Donato, Debora   +2 more
openaire   +3 more sources

FSC or Business as usual? Social impacts of forest certification in Cameroon [PDF]

, 2011
FSC or Business as usual? Social impacts of forest certification in Cameroon The paradigm of Sustainable Forest Management is central in the forestry laws enacted over the latest decades in the Congo Basin countries. However its implementation, and hence
Cerutti, Paolo Omar, Lescuyer, Guillaume, Tsanga, Raphael   +2 more
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source