Results 101 to 110 of about 499,899 (298)
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Fertilisation with nutrient optimisation has in Sweden resulted in large increases in volume growth in young stands of Norway spruce. There are, however, environmental concerns about repeated fertilisation and one is the risk of nutrient leakage to ...
Per-Ola Hedwall +5 more
doaj +1 more source
Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla +10 more
wiley +1 more source
The Feasibility of Harvesting and Extraction of Logging Residues in Sabah [PDF]
Effective harvesting and utilisation of log and logging residues are important, in achieving the sustainable forest management and to maximize the government revenue, in the light of declining supply of conventional logs.
Ahlan, Joseph
core +1 more source
The effect of mechanical site preparation on sandy soil properties in Scots pine plantations
Sandy soils represent an extreme environment for tree growth. Traditionally, site preparation before planting involves removing logging residues (LRR) and ploughing. An alternative method is incorporating logging residues (LRI) into the topsoil which may
Ján Židó +3 more
doaj +1 more source
Production Costs and Markets for Pellet Chips: Case Studies in Northern Sweden
Increasing use of woody fuels requires that nontraditional types of raw materials are exploited, including logging residues and small-diameter trees.
Gunnar Eriksson +4 more
doaj +1 more source
On the Noncommutative Residue for Pseudodifferential Operators with log-Polyhomogeneous Symbols
LaTeX2e, 35 pages; v2 16 Sept 1997, section on Kontsevich-Vishik added, Final version, 10 July 1998, minor corrections, to appear in Ann. Glob.
openaire +2 more sources
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi +3 more
wiley +1 more source
The Economic and Environmental Effects of an EU Ban on Illegal Logging Imports. Insights from a CGE Assessment [PDF]
Illegal logging is widely recognized as a major economic problem and one of the causes of environmental degradation. Increasing awareness of its negative effects has fostered a wide range of proposals to combat it by major international conservation ...
Renato Rosa +2 more
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