Results 61 to 70 of about 499,899 (298)

A Comparison of Forest Biomass and Conventional Harvesting Effects on Estimated Erosion, Best Management Practice Implementation, Ground Cover, and Residual Woody Debris in Virginia

open access: yesBiomass, 2023
Expanding markets for renewable energy feedstocks have increased demand for woody biomass. Concerns associated with forest biomass harvesting include increased erosion, the applicability of conventional forestry Best Management Practices (BMPs) for ...
Austin M. Garren   +5 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A Simplified Method of Sampling Logging Residue

open access: yesThe Forestry Chronicle, 1970
The line intersect technique for estimating the volume of logging residue was field tested in British Columbia from 1965 to 1967. Residual volumes could be satisfactorily estimated from two sets of sampling lines oriented at right angles. Angular orientation of the residue to the sampling lines could be represented by a constant factor on both tractor-
openaire   +1 more source

Transpirational Drying of Stacked Logging Residue Logs for Wood Fuel Chips.

open access: yesJournal of the Japanese Forest Society, 2010
木質バイオマスをボイラ燃料として用いるには乾燥が必要である。本研究は長さ2 mのスギ皮付き丸太をアスファルト舗装された土場で, 方形状および三角形状にはえ積みし, 12月から9月までの約9カ月間, 天然乾燥し, その含水率の推移を分析した。その結果, 約9カ月間乾燥することで平均含水率が約140%から40%まで低下した。方形積みと三角積みの積み方の違いは, 含水率の低下に影響を与えなかった。また, 方形積み, 三角積みともに表層部の丸太が乾燥し, 内部と比較すると含水率で2倍以上の違いがあった。表層の丸太内の含水率の偏りは小さかったが, 内部の丸太内の偏りは大きかった。さらに, 丸太の設置環境によっても乾燥後における丸太内の水分分布に偏りができた。そのため ...
Ichihara, Takashi   +9 more
openaire   +2 more sources

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Retaining eucalyptus harvest residues promotes different pathways for particulate and mineral‐associated organic matter

open access: yesEcosphere, 2021
Eucalyptus plantations have replaced other (agro)ecosystems over 5.6 Mha in Brazil. While these plantations rapidly accumulate carbon (C) in their biomass, the C storage in living forest biomass is transient, and thus, longer‐term sustainability relies ...
Gabriel W. D. Ferreira   +5 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

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