Results 171 to 180 of about 206 (205)
GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy
Advanced Science, EarlyView.Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu +11 more
wiley +1 more source
Synergistic Mn‐MOF Activation of Pistol Ribozymes for Cancer Immunotherapy
Advanced Science, EarlyView.A Mn2+‐based metal–organic framework delivers a catalytic Pistol ribozyme for targeted PD‐L1 mRNA cleavage in tumor cells, with the released Mn2+ not only inducing immune activation in immune cells but also increasing the Pistol ribozyme catalytic activity.
Ming Zhao +10 more
wiley +1 more source
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Preferential Logics are X-logics
Journal of Logic and Computation, 2001zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Siegel, Pierre +2 more
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Dialogue, 1997
RésuméLe logicisme de Frege engage à deux thèses: (1) les vérités de l'arithmétique sont ipso facto vérités de logique; (2) les nombres naturels sont des objets. Dans cet article je pose la question: quelle conception de la logique est-elle requise pour étayer ces thèses? Je soutiens qu'il existe une conception appropriée et naturelle de la logique, en
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RésuméLe logicisme de Frege engage à deux thèses: (1) les vérités de l'arithmétique sont ipso facto vérités de logique; (2) les nombres naturels sont des objets. Dans cet article je pose la question: quelle conception de la logique est-elle requise pour étayer ces thèses? Je soutiens qu'il existe une conception appropriée et naturelle de la logique, en
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Modal Logic As Dialogical Logic
Synthese, 2001The title reflects my conviction that, viewed semantically, modal logic is fundamentally dialogical; this conviction is based on the key role played by the notion of bisimulation in modal model theory. But this dialogical conception of modal logic does not seem to apply to modal proof theory, which is notoriously messy.
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Theoretical Linguistics, 1987
The author himself characterises his work as a ``survey of the secret charms of logical syntax''. It really is. The different fragments of logical syntax (predicate and propositional calculus etc.) are considered from the grammar-theoretical point of view. The paper contains interesting results about their context-freeness, regularity etc.
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The author himself characterises his work as a ``survey of the secret charms of logical syntax''. It really is. The different fragments of logical syntax (predicate and propositional calculus etc.) are considered from the grammar-theoretical point of view. The paper contains interesting results about their context-freeness, regularity etc.
openaire +4 more sources
Expert logic v . operator logic
IFAC Proceedings Volumes, 1985Expert logic and operator logic, as two poles of a continuum, are analysed as bodies of knowledge (of functioning and of utilization), as modes of reasoning (deduction, induction, analogy, etc.), and as cognitive strategies (“problem-positioning” vs problem solving).
M. de Montmollin, V. De Keyser
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PSA: Proceedings of the Biennial Meeting of the Philosophy of Science Association, 1974
One can and often does use the word ‘logic’ in a variety of metaphorical ways, speaking of “the logic of the situation”, “the logic of events”, “the logic of history”, and so on. No harm is done, so long as one realizes that these usages are metaphorical, and should not be given any deeper significance – at least without extensive discussion of the ...
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One can and often does use the word ‘logic’ in a variety of metaphorical ways, speaking of “the logic of the situation”, “the logic of events”, “the logic of history”, and so on. No harm is done, so long as one realizes that these usages are metaphorical, and should not be given any deeper significance – at least without extensive discussion of the ...
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Embedding Logics into Product Logic
Studia Logica, 1998zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Baaz, Matthias +3 more
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Journal of the History of Philosophy, 1979
One of the problems involved in doing the history of philosophy is reinterpreting past philosophers in such a way that the relevance of their work to contemporary discussion can become clear. In doing so one often finds that certain doctrines to which a philosopher himself attached great significance may not be central to a particular line of his ...
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One of the problems involved in doing the history of philosophy is reinterpreting past philosophers in such a way that the relevance of their work to contemporary discussion can become clear. In doing so one often finds that certain doctrines to which a philosopher himself attached great significance may not be central to a particular line of his ...
openaire +1 more source