Results 21 to 30 of about 5,559,621 (201)
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant +7 more
wiley +1 more source
The formation of ordered Z (Glu342Lys) α1‐antitrypsin polymers in hepatocytes is central to liver disease in α1‐antitrypsin deficiency. In vitro experiments have identified an intermediate conformational state (M*) that precedes polymer formation, but ...
R. Ronzoni +7 more
semanticscholar +1 more source
Influence of Molecular Genetic Classes on Behavior in Prader‐Willi Syndrome
ABSTRACT A wide range of behavioral phenotypes has been described in PWS patients including autism spectrum disorder (ASD). The prevalence of behavioral disorders was studied in 292 participants over 3 years with genetically confirmed PWS (N = 164 females and N = 128 males) with deletion (N = 182) and mUPD (maternal uniparental disomy) (N = 99).
Ranim Mahmoud +6 more
wiley +1 more source
Abstract The Pleistocene is a key period for understanding the evolutionary history and palaeobiogeography of the European rabbit (Oryctolagus cuniculus). The species was first documented in southeastern Iberia at the beginning of the Middle Pleistocene and appears to have rapidly spread throughout Southwestern Europe, where it was found in numerous ...
Maxime Pelletier
wiley +1 more source
. Pico-plankton and nano-plankton are generally thought to represent a negligible fraction of the total particulate organic carbon (POC) export flux in oligotrophic gyres due to their small size, slow individual sinking rates, and tight grazer control ...
M. Lomas, S. B. Moran
semanticscholar +1 more source
Abstract While large language models (LLMs) have shown promise as learning tools for medical education, their reported accuracy on multiple‐choice questions (MCQs) varies widely across studies, necessitating synthesis. This meta‐analysis synthesizes LLM accuracy on text‐based MCQs from biomedical disciplines and USMLE Step 1‐level content and explores ...
Colleen M. Cheverko +26 more
wiley +1 more source
AI voice journaling for future language teachers: A path to well‐being through reflective practices
Abstract This study aimed to explore the perceived impact of using an AI‐powered voice journaling app in overcoming the challenges and stressors encountered by senior students enrolled in teaching practicum at an English Language Teaching Bachelor's programme.
Bora Demir, Duygu Özdemir
wiley +1 more source
Flourishing through adventure learning: A (semi)cautionary tale
Abstract Studies suggest that adventure learning can develop children's cognitive skills and promote social and emotional learning. However, evidence is needed as to whether the design of adventure learning—school‐based or external/residential—plays a role in that development/promotion, and whether learning gains are maintained.
Ben Willis, Sarah Reaney‐Wood
wiley +1 more source
Exploring Healthcare Continuity in Pediatric‐Onset Multiple Sclerosis in the United States
ABSTRACT Objective Little is known about shifting from pediatric to adult‐focused multiple sclerosis (MS) care. This study aims to explore transition of care and follow‐up in the US pediatric‐onset MS (POMS) population. Methods Surveys were distributed to 10 sites in the US Network of Pediatric MS Centers (US NPMSC) about transition‐of‐care practices ...
Aaron W. Abrams +31 more
wiley +1 more source
Abstract Background Arterial stiffness is a crucial factor in determining an increase in systolic blood pressure and pulse pressure and can also predict the development of cardiovascular disease (CVD). The purpose of this study was to examine the relationship between arterial stiffness and future CVD.
Susan Darroudi +10 more
wiley +1 more source

