Results 91 to 100 of about 1,649 (190)

WHO fungal priority pathogens list to guide research, development and public health action [PDF]

, 2022
Infectious diseases are among the top causes of mortality and a leading cause of disability worldwide. Drug-resistant bacterial infections are estimated to directly cause 1.27 million deaths and to contribute to approximately 4.95 million deaths every ...
Alastruey-Izquierdo, Ana, World Health Organization. Antimicrobial Resistance Division, World Health Organization. Control of Neglected Tropical Diseases, World Health Organization. Global Coordination and Partnership   +3 more
core  

The Significance of Mono‐ and Dual‐Effective Agents in the Development of New Antifungal Strategies

Chemical Biology &Drug Design, Volume 105, Issue 1, January 2025.
The future of treating challenging fungal infections lies in novel therapies targeting new antifungal targets, overcoming resistance mechanisms, and exploring innovative dual inhibitors. ABSTRACT Invasive fungal infections (IFIs) pose significant challenges in clinical settings, particularly due to their high morbidity and mortality rates.
Cengiz Zobi, Oztekin Algul
wiley   +1 more source

Airway Mycobiota—Microbiota During Pulmonary Exacerbation of Cystic Fibrosis Patients: A Culture and Targeted Sequencing Study

Mycoses, Volume 68, Issue 1, January 2025.
ABSTRACT Background The airways of patients with cystic fibrosis (pwCF) harbour complex fungal and bacterial microbiota involved in pulmonary exacerbations (PEx) and requiring antimicrobial treatment. Descriptive studies analysing bacterial and fungal microbiota concomitantly are scarce, especially using both culture and high‐throughput‐sequencing (HTS)
Cécile Angebault, Louise‐Eva Vandenborght, Laurence Bassinet, Nathalie Wizla, Agnès Ferroni, Rodrigue Dessein, Natacha Remus, Caroline Thumerelle, Nathalie Fauchet, Ralph Epaud, Laurence Delhaes, Françoise Botterel   +11 more
wiley   +1 more source

Microglial immune response is impaired against the neurotropic fungusLomentospora prolificans

Cellular Microbiology, 2018
Lomentospora (Scedosporium) prolificans is an opportunistic pathogen capable of causing invasive infections in immunocompromised patients. The fungus is able to disseminate via the bloodstream finally arriving at the central nervous system producing neurological symptoms and, in many cases, patient death.
Aize Pellon, Andoni Ramirez‐Garcia, Xabier Guruceaga, Alazne Zabala, Idoia Buldain, Aitziber Antoran, Juan Anguita, Aitor Rementeria, Carlos Matute, Fernando L. Hernando   +9 more
openaire   +3 more sources

Antibiofilm activity of antifungal drugs, including the novel drug olorofim, against Lomentospora prolificans

Journal of Antimicrobial Chemotherapy, 2020
Abstract Objectives Patients with immunodeficiency or cystic fibrosis frequently suffer from respiratory fungal infections. In particular, biofilm-associated fungi cause refractory infection manifestations, linked to increased resistance to anti-infective agents.
Joerg Steinmann, Peter-Michael Rath, Jan Buer, Ann-Kathrin Weisner, Silke Dittmer, Lisa Kirchhoff   +5 more
openaire   +3 more sources

Longitudinal Characterization of the Gut Bacterial and Fungal Communities in Yaks

Journal of Fungi, 2021
Development phases are important in maturing immune systems, intestinal functions, and metabolism for the construction, structure, and diversity of microbiome in the intestine during the entire life.
Yaping Wang, Yuhang Fu, Yuanyuan He, Muhammad Fakhar-e-Alam Kulyar, Mudassar Iqbal, Kun Li, Jiaguo Liu   +6 more
doaj   +1 more source

Using Interleukin 6 and 8 in Blood and Bronchoalveolar Lavage Fluid to Predict Survival in Hematological Malignancy Patients With Suspected Pulmonary Mold Infection. [PDF]

, 2019
Background: Molds and other pathogens induce elevated levels of several cytokines, including interleukin (IL)-6 and IL-8. The objective of this study was to investigate the prognostic value of IL-6 and IL-8 as well as fungal biomarkers in blood and ...
Eigl, Susanne, Flick, Holger, Heldt, Sven, Hoenigl, Martin, Jenks, Jeffrey D, Krause, Robert, Neumeister, Peter, Prattes, Juergen, Prüller, Florian, Rabensteiner, Jasmin, Rawlings, Stephen A, Strohmaier, Heimo, Wölfler, Albert   +12 more
core   +1 more source

Fungal communities in pressmud composting harbour beneficial and detrimental fungi for human welfare [PDF]

, 2016
Pressmud is a substrate derived from sugarcane juice filtrate, and around 26-40  kg of this residue are produced per ton of sugarcane. It is mainly used as fertilizer in crops, and its application in the field is often made without any prior treatment ...
Barbosa, Fernando Nogueira, de Oliveira, Tássio Brito, Ferro, Milene, Gomes, Eleni, Lopes, Viviane Cristina Padilha, Meirelles, Lucas Andrade, Rodrigues, Andre, Sette, Lara Durães   +7 more
core   +1 more source

Case Series of Rare Fungal Keratitides: Experiences from a Quaternary Eye Hospital in Sydney, Australia

, 2023
The present article reports on the management of six different and rare cases of fungal keratitides, two of which have never been documented in previous literature.
Coroneo, MT , Hong, SC, Petsoglou, C, Trinh, T, Xuan, R   +4 more
core   +1 more source

P306 Scedosporium spp. and Lomentospora prolificans, fungal agents with unexpected vascular tropism

Medical Mycology, 2022
Abstract Poster session 2, September 22, 2022, 12:30 PM - 1:30 PM   Objectives Invasive scedosporiosis and lomentosporiosis are deadly fungal infections due to Scedosporium spp. and Lomentospora prolificans.
Vignals, Carole, Lanternier, Fanny, Garcia-Hermoso, Dea, Emmerich, Joseph, Bronnimann, Didier   +4 more
openaire   +1 more source