Results 211 to 220 of about 225,232 (252)

Exploring cattle structural variation in the era of long reads, pangenome graphs, and near-complete assemblies. [PDF]

J Anim Sci Biotechnol
Liu GE.
europepmc   +1 more source

esloco: simulation-based estimation of local coverage in long-read DNA sequencing. [PDF]

Bioinformatics
Weich A, Lischer C, Vera J.
europepmc   +1 more source

Generation and characterization of a HEK293 cell line optimized for recombinant adeno-associated virus production. [PDF]

Biotechnol Rep (Amst)
Vona M, Bodenmann I, Perrenoud MA, Buchs R, Yasli PK, Nanni L, Daveau R, Félix A, Stolte J, Hov AK, Chollet B, Schuepbach T, Ley D, Guzman E, Fisch I, Mermod N.   +15 more
europepmc   +1 more source

Draft genome sequences of the pathogenic fungi <i>Scedosporium aurantiacum</i> and <i>Scedosporium apiospermum</i> from clinical isolates. [PDF]

Microbiol Resour Announc
Montgomery ST, Rezaee H, Sbaraini N, Iszatt J, Mantjani L, Kidd SE, Chooi Y-H, Garratt LW.   +7 more
europepmc   +1 more source

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Fast and Accurate Algorithms for Mapping and Aligning Long Reads

Journal of Computational Biology, 2021
For DNA sequence analysis, we are facing challenging tasks such as the identification of structural variants, sequencing repetitive regions, and phasing of alleles. Those challenging tasks suffer from the short length of sequencing reads, where each read may cover less than 2 single nucleotide polymorphism (SNP), or less than two occurrences of a ...
Wen, Yang, Lusheng, Wang
openaire   +2 more sources

An Efficient Parallel Sketch-Based Algorithmic Workflow for Mapping Long Reads

IEEE Transactions on Computational Biology and Bioinformatics, 2023
1AbstractLong read technologies are continuing to evolve at a rapid pace, with the latest of the high fidelity technologies delivering reads over 10Kbp with high accuracy (99.9%). Classical long read assemblers produce assemblies directly from long reads.
Tazin Rahman, Oieswarya Bhowmik, Ananth Kalyanaraman   +2 more
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CRISPR-Cas9 Long-Read Sequencing for Mapping Transgenes in the Mouse Genome

The CRISPR Journal, 2023
Microinjected transgenes, both large and small, are known to insert randomly into the mouse genome. Traditional methods of mapping a transgene are challenging, thus complicating breeding strategies and accurate interpretation of phenotypes, particularly when a transgene disrupts critical coding or noncoding sequences. As the vast majority of transgenic
W. Bart Bryant, Allison Yang, Susan H. Griffin, Wei Zhang, Ashiq M. Rafiq, Weiping Han, Ferenc Deak, Mary Katherine Mills, Xiaochun Long, Joseph M. Miano   +9 more
openaire   +2 more sources