Results 101 to 110 of about 4,459,968 (325)

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

open access: yesArthritis Care &Research, EarlyView.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen   +4 more
wiley   +1 more source

Store-Operated Calcium Entry Is Required for mGluR-Dependent Long Term Depression in Cortical Neurons

open access: yesFrontiers in Cellular Neuroscience, 2017
Store-operated calcium entry (SOCE) is a Calcium (Ca2+) influx pathway activated by depletion of intracellular stores that occurs in eukaryotic cells. In neurons, the presence and functions of SOCE are still in question.
Paloma González-Sánchez   +9 more
doaj   +1 more source

The Effect of Acceptance Training on Psychological and Physical Health Outcomes in Elders with Chronic Conditions [PDF]

open access: yes, 2011
This pilot trial investigated the short and long-term effects of Acceptance Training (ACT) intervention on acceptance, perceived health, functional status, anxiety, and depression in elders with chronic conditions living in retirement communities (RCs ...
Bekhet, Abir K.   +4 more
core   +2 more sources

Long-term trends in depression among women separated from abusive partners [PDF]

open access: yes, 2003
This study tested a cumulative adversity hypothesis, where differences in postseparation stressors among battered women were expected to lead to a widening gap in levels of women’s depression over time.
Anderson, D.K   +4 more
core   +1 more source

Clinical Outcomes Of Patients Within The Rheumatoid Arthritis Care Pathway Cohort At a Tertiary Care Integrated Delivery Network: A Comparison To Usual Care

open access: yesArthritis Care &Research, Accepted Article.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multi‐disciplinary team‐based care. Clinical and insurance claims data were extracted to compare
Tarun Sharma   +7 more
wiley   +1 more source

Exercise is medicine for depression: even when the “pill” is small

open access: yesNeuropsychiatric Disease and Treatment, 2016
Mats Hallgren,1 Davy Vancampfort,2,3 Brendon Stubbs4,5 1Department of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden; 2Department of Rehabilitation Sciences, 3University Psychiatric Centre – KU Leuven, KU Leuven &ndash ...
Hallgren M, Vancampfort D, Stubbs B
doaj  

Sex difference in synaptic plasticity in the anterior cingulate cortex of adult mice

open access: yesMolecular Brain, 2020
Sex differences in certain types of pain sensitivity and emotional responses have been previously reported. Synaptic plasticity is a key cellular mechanism for pain perception and emotional regulation, including long-term potentiation (LTP) and long-term
Ren-Hao Liu   +3 more
doaj   +1 more source

Effects of environmental enrichment on behavioral responses to novelty, learning, and memory, and the circadian rhythm in cortisol in growing pigs [PDF]

open access: yes, 2000
Previously we showed that pigs reared in an enriched environment had higher baseline salivary cortisol concentrations during the light period than pigs reared under barren conditions.
Blokhuis, Harry J.,   +6 more
core   +1 more source

Temporal trends in and associations with nonsteroidal anti‐inflammatory drug prescription in adult and pediatric patients with inflammatory bowel disease

open access: yesArthritis Care &Research, Accepted Article.
Objective Recent inflammatory bowel disease (IBD) treatment guidelines have recommended against NSAID use despite prevalent musculoskeletal symptoms and opioid overuse in this population. Given the discordance between changing national guidelines and potential clinical utility, we sought to assess national temporal trends in prescription NSAID and ...
Adam S. Mayer   +5 more
wiley   +1 more source

Integrated plasticity at inhibitory and excitatory synapses in the cerebellar circuit

open access: yesFrontiers in Cellular Neuroscience, 2015
The way long-term potentiation (LTP) and depression (LTD) are integrated within the different synapses of brain neuronal circuits is poorly understood.
Lisa eMapelli   +7 more
doaj   +1 more source

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