Results 101 to 110 of about 4,254,343 (401)
Major Depressive Disorder (MDD) presents considerable challenges to diagnosis and management due to symptom variability across time. Only recent work has highlighted the clinical implications for interrogating depression symptom variability.
George D. Price+4 more
doaj +1 more source
MASON-NLP at eRisk 2023: Deep Learning-Based Detection of Depression Symptoms from Social Media Texts [PDF]
Depression is a mental health disorder that has a profound impact on people's lives. Recent research suggests that signs of depression can be detected in the way individuals communicate, both through spoken words and written texts. In particular, social media posts are a rich and convenient text source that we may examine for depressive symptoms.
arxiv
OBJECTIVE To evaluate long-term safety and efficacy of esketamine nasal spray plus a new oral antidepressant (OAD) in patients with treatment-resistant depression (TRD).
E. Wajs+20 more
semanticscholar +1 more source
Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome [PDF]
Fragile X syndrome, the most commonly known genetic cause of autism, is due to loss of the fragile X mental retardation protein, which regulates signal transduction at metabotropic glutamate receptor-5 in the brain.
DiPatrizio, Nicholas V.+12 more
core +5 more sources
The ultraselective H2S detection of the ZIF‐L/SnS2 heterostructure is demonstrated. The introduction of 2‐dimensional (2D) breathable ZIF‐L results in a substantial increase in H2S selectivity attributable to the molecular sieving effect, which impedes the permeation of gases with large kinetic diameters and high polarity.
Soo Min Lee+7 more
wiley +1 more source
Nitric Oxide Facilitates Long-Term Potentiation, But Not Long-Term Depression [PDF]
Reports that nitric oxide synthase (NOS) inhibition prevents the induction of long-term potentiation (LTP) have been controversial. Recent evidence suggests that NO may help to regulate the threshold for LTP induction. We have tested this hypothesis by examining the effects of stimulus frequency and train duration on synaptic plasticity in the presence
Peter L. Malen+2 more
openaire +3 more sources
A materials and device design concept that comprises a self‐assembled ultra‐thin epitaxial ion‐transporting layer, an amorphous oxide overcoat oxygen‐blocking layer, and a partial filament formed during an electroforming step is proposed for low‐current multilevel resistive switching devices.
Ming Xiao+17 more
wiley +1 more source
Sex difference in synaptic plasticity in the anterior cingulate cortex of adult mice
Sex differences in certain types of pain sensitivity and emotional responses have been previously reported. Synaptic plasticity is a key cellular mechanism for pain perception and emotional regulation, including long-term potentiation (LTP) and long-term
Ren-Hao Liu+3 more
doaj +1 more source
Left Out Of The Economy: Much More Must Be Done to Help Consumers Enter the Workforce [PDF]
[Excerpt] Unemployment leads directly to poverty— a situation that people with mental illness are three times more likely to be in than people without disabilities. Cornell University researchers reported in 2005 that people with psychiatric disabilities
Marrone, Joe
core +1 more source
Genome-wide polygenic scoring for a 14-year long-term average depression phenotype [PDF]
Background: Despite moderate heritability estimates for depression-related phenotypes, few robust genetic predictors have been identified. Potential explanations for this discrepancy include the use of phenotypic measures taken from a single time point ...
Chang, Shun-Chiao+9 more
core +1 more source