Results 121 to 130 of about 525,185 (258)

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

Advanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum, Leo A. H. Zeef, Lee A. Stevens, Marco A. N. Domingos, Susan J. Kimber, Mahetab H. Amer   +5 more
wiley   +1 more source

Modeling the effects of molecular crowding on cerebellar long term depression

BMC Neuroscience, 2012
Deans Horace, Santamaria Fidel
doaj   +1 more source

PKMζ is necessary for long-term depression and long-term potentiation in the medial prefrontal cortex. [PDF]

J Physiol
Kniffin AR, English EA, Briand LA.
europepmc   +1 more source

HCN1 channels mediate mu opioid receptor long-term depression at insular cortex inputs to the dorsal striatum. [PDF]

J Physiol, 2022
Munoz B, Fritz BM, Yin F, Atwood BK.
europepmc   +1 more source

Evaluation of the Dual Impact of Nanotechnologies on Health and Environment Through Alternative Bridging Models

Advanced Healthcare Materials, EarlyView.
This review explores how alternative invertebrate and small‐vertebrate models advance the evaluation of nanomaterials across medicine and environmental science. By bridging cellular and organismal levels, these models enable integrated assessment of toxicity, biodistribution, and therapeutic performance.
Marie Celine Lefevre, Margherita Bernardeschi, Matteo Battaglini, Gianni Ciofani   +3 more
wiley   +1 more source

Incubation with tau aggregates increases hippocampal circuit excitability and enhances long-term depression in acute mouse hippocampal slices. [PDF]

Front Neural Circuits
Wang A, Richardson A, Emmett I, Friedmann D, Bakker S, Richardson M, Hill E, Wall M.   +7 more
europepmc   +1 more source

Long-term depression in neurons involves temporal and ultra-structural dynamics of phosphatidylinositol-4,5-bisphosphate relying on PIP5K, PTEN and PLC. [PDF]

Commun Biol, 2023
Hofbrucker-MacKenzie SA, Seemann E, Westermann M, Qualmann B, Kessels MM.   +4 more
europepmc   +1 more source

Water Permeates and Plasticizes Amorphous Carbon Dots: Unraveling the Inner Accessibility of the Nanoparticles by Glass Transition Studies

Advanced Materials, EarlyView.
The water permeability of amorphous carbon dots (CDs) is demonstrated by investigating their plasticization. Novel polyamide‐based and amorphous nanoparticles are synthesized by controlling their inner packing density. Water plasticization is evidenced by the decrease of the CDs glass transition temperature with increasing the hydration degree.
Elisa Sturabotti, Valerio Di Lisio, Lucia Cardo, Alessandro Camilli, Estela Moretón Alfonsín, Daniele Cangialosi, Amaia Iturrospe Ibarra, Arantxa Arbe, Maurizio Prato   +8 more
wiley   +1 more source

Perisynaptic Astroglial Response to In Vivo Long-Term Potentiation and Concurrent Long-Term Depression in the Hippocampal Dentate Gyrus. [PDF]

J Neurosci
Nam AJ, Kuwajima M, Parker PH, Bowden JB, Abraham WC, Harris KM.   +5 more
europepmc   +1 more source

Distinct predictors of short- versus long-term depression outcomes following electroconvulsive therapy. [PDF]

J Psychiatr Res, 2022
Mickey BJ, Ginsburg Y, Jensen E, Maixner DF.   +3 more
europepmc   +1 more source