Results 181 to 190 of about 480,748 (291)

Chronic Psychological Stress Induces Cardiomyocyte Hypertrophy Through Corticosterone‐Glucocorticoid Receptor‐LAMA5 Axis

Advanced Science, EarlyView.
In vivo experiments suggest that cardiomyocyte hypertrophy is an early manifestation of cardiac pathological changes induced by chronic psychological stress. In vivo and in vitro experiments suggest that the corticosterone‐glucocorticoid receptor‐LAMA5 axis mediates cardiomyocyte hypertrophy induced by chronic psychological stress. The clinical results
Chuanjing Zhang, Yongfei Song, Xiaojun Jin, Qingbo Xu, Honghua Ye, Zhuonan Wu, Hui Lin, Jiale Hu, Chen Huang, Jianqing Zhou, Jiangfang Lian   +10 more
wiley   +1 more source

Synaptopodin is required for long-term depression at Schaffer collateral-CA1 synapses. [PDF]

Mol Brain
Inglebert Y, Wu PY, Tourbina-Kolomiets J, Dang CL, McKinney RA.   +4 more
europepmc   +1 more source

Age-Dependent Contributions of NMDA Receptors and L-Type Calcium Channels to Long-Term Depression in the Piriform Cortex. [PDF]

Int J Mol Sci, 2021
Rajani V, Maziar A, Man KNM, Hell JW, Yuan Q.   +4 more
europepmc   +1 more source

Brain‐derived neurotrophic factor blocks long‐term depression in solitary neurones cultured from rat visual cortex

, 2000
Eiji Kumura, Fumitaka Kimura, Nobuaki Taniguchi, Tadaharu Tsumoto   +3 more
openalex   +2 more sources

The Maudsley long-term follow-up of child and adolescent depression [PDF]

, 2002
Martín Knapp, Paul McCrone, Éric Fombonne, Jennifer Beecham, Gail Wostear   +4 more
openalex   +1 more source

A High‐Fidelity RNA‐Targeting Cas13X Downregulates Connexin43 in Macroglia: A Novel Neuroprotective Strategy for Glaucoma

Advanced Science, EarlyView.
This study highlights the role of connexin43 (Cx43) in mediating glia activation and neuroinflammation in glaucoma. Using Cx43 knockout mice, it is shown that macroglial cells‐derived Cx43 modulates microglial activation, proliferation, migration, and polarization.
Guoli Zhao, Zhen Li, Ming‐Jie Zhao, Shu‐Ying Li, Qing Xia, Shuoyu Xu, Yu Zhang, Yi Wang, Fang Li, Yu‐Ling Liu, Yun‐Hui Guo, Ruo‐Xi Xu, Han Zhou, Hong Zhou, Wen‐Wen Ding, Yong‐Chen Wang, Yanying Miao, Zhongfeng Wang   +17 more
wiley   +1 more source

Interplay of hippocampal long-term potentiation and long-term depression in enabling memory representations. [PDF]

Philos Trans R Soc Lond B Biol Sci
Hagena H, Manahan-Vaughan D.
europepmc   +1 more source

Disruption of Long-Term Depression Potentiates Latent Inhibition: Key Role for Central Nucleus of the Amygdala. [PDF]

Int J Neuropsychopharmacol, 2021
Ashby DM, Dias C, Aleksandrova LR, Lapish CC, Wang YT, Phillips AG.   +5 more
europepmc   +1 more source

Involvement of Presynaptic N-Methyl-D-Aspartate Receptors in Cerebellar Long-Term Depression [PDF]

, 2002
Mariano Casado, Philippe Isope, Philippe Ascher   +2 more
openalex   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source