Mapping dynamic interactions among cognitive biases in depression [PDF]
, 2020 Depression is theorized to be caused in part by biased cognitive processing of emotional information. Yet, prior research has adopted a reductionist approach that does not characterize how biases in cognitive processes such as attention and memory work ...
Bernstein, Amit +3 more
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Rho Signaling in Synaptic Plasticity, Memory, and Brain Disorders
Frontiers in Cell and Developmental Biology, 2021 Memory impairments are associated with many brain disorders such as autism, Alzheimer’s disease, and depression. Forming memories involves modifications of synaptic transmission and spine morphology.
Haorui Zhang +7 more
doaj +1 more source
Dependence receptor involvement in subtilisin-induced long-term depression and in long-term potentiation [PDF]
, 2016 The serine protease subtilisin induces a form of long-term depression (LTD) which is accompanied by a reduced expression of the axo-dendritic guidance molecule Unco-ordinated-5C (Unc-5C).
Darlington, L. Gail +2 more
core +1 more source
Mental Illness, 2012 This study is a follow-up of inpatients diagnosed with severe depression/melancholia between 1956 and 1969. During this period, all inpatients at the Department of Psychiatry, University Hospital, Lund, were rated on a multidimensional diagnostic ...
Lisa Crona, Louise Brådvik
doaj +1 more source
Frontiers in Cellular Neuroscience, 2019 Neuroactive estrogenic and androgenic steroids influence synaptic transmission, finely modulating synaptic plasticity in several brain regions including the hippocampus.
Alessandro Tozzi +9 more
doaj +1 more source
Stochastic Induction of Long-Term Potentiation and Long-Term Depression [PDF]
Scientific Reports, 2016 AbstractLong-term depression (LTD) and long-term potentiation (LTP) of granule-Purkinje cell synapses are persistent synaptic alterations induced by high and low rises of the intracellular calcium ion concentration ([Ca2+]), respectively. The occurrence of LTD involves the activation of a positive feedback loop formed by protein kinase C, phospholipase
Fábio M. Simões-de-Souza +2 more
openaire +3 more sources
Long-term effectiveness and cost-effectiveness of cognitive behavioural therapy as an adjunct to pharmacotherapy for treatment-resistant depression in primary care: follow-up of the CoBalT randomised controlled trial [PDF]
, 2016 Background: Cognitive behavioural therapy (CBT) is an effective treatment for people whose depression has not responded to antidepressants. However, the long-term outcome is unknown.
Campbell, John +12 more
core +2 more sources
Long-Term Depression of mGluR1 Signaling [PDF]
Neuron, 2007 Glutamate produces both fast excitation through activation of ionotropic receptors and slower actions through metabotropic receptors (mGluRs). To date, ionotropic but not metabotropic neurotransmission has been shown to undergo long-term synaptic potentiation and depression.
Paul F. Worley +4 more
openaire +3 more sources
NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD).
Cold Spring Harbor Perspectives in Biology, 2012 Long-term potentiation and long-term depression (LTP/LTD) can be elicited by activating N-methyl-d-aspartate (NMDA)-type glutamate receptors, typically by the coincident activity of pre- and postsynaptic neurons.
C. Lüscher, R. Malenka
semanticscholar +1 more source
Shorter duration of slow wave sleep is related to symptoms of depression in patients with epilepsy [PDF]
, 2023 Slow wave sleep duration and spectral abnormalities are related to both epilepsy and depression, but it is unclear how depressive symptoms in patients with epilepsy are affected by slow wave sleep duration and clinical factors, and how the spectral characteristics of slow wave sleep reflect a potential interaction of epilepsy and depression.
arxiv +1 more source