Results 21 to 30 of about 470,220 (291)
Long-term obesity is associated with depression and neuroinflammation [PDF]
Archives of Endocrinology and Metabolism, 2021 Obesity is characterized by a state of chronic, low-intensity systemic inflammation frequently associated with insulin resistance and dyslipidemia.Given that chronic inflammation has been implicated in the pathogenesis of mood disorders, we investigated if chronic obesity that was initiated early in life - lasting through adulthood - could be more ...
Fernanda B. Lorena +8 more
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Malang Neurology Journal, 2015 Intracellular processes in neurons begins when the extracellular chemical signals such as neurotransmitters, attached at specific receptors which then activates a cascade of intracellular reactions included herein are proteins GTP, second messengers ...
Shahdevi Nandar Kurniawan
doaj +1 more source
The demise of the synapse as the locus of memory: A looming paradigm shift?
Frontiers in Systems Neuroscience, 2016 Synaptic plasticity is widely considered to be the neurobiological basis of learning and memory by neuroscientists and researchers in adjacent fields, though diverging opinions are increasingly being recognised. From the perspective of what we might call
Patrick C. Trettenbrein +1 more
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Motor cortical plasticity induced by motor learning through mental practice.
Frontiers in Behavioral Neuroscience, 2015 Several investigations suggest that actual and mental actions trigger similar neural substrates. Motor learning via physical practice results in long-term potentiation (LTP)-like plasticity processes, namely potentiation of M1 and a temporary occlusion ...
Laura eAvanzino +5 more
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TIME OF DIABETIC ULCER FOOT SUFFERING AND DEPRESSION SYMPTOMS IN ULIN GENERAL HOSPITAL BANJARMASIN
Berkala Kedokteran, 2017 : Diabetic foot ulcers are one kind of chronic complication of diabetes mellitus in the form of an open wound on the skin’s surface and may be accompanied by local tissue death. Long term suffering of diabetic foot ulcers with physical and psychological
Rizka Dwi Puteri +2 more
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Climbing fiber signaling and cerebellar gain control
Frontiers in Cellular Neuroscience, 2009 The physiology of climbing fiber signals in cerebellar Purkinje cells has been studied since the early days of electrophysiology. Both the climbing fiber-evoked complex spike and the role of climbing fiber activity in the induction of long-term ...
Gen Ohtsuki +4 more
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A Practical Guide to Using CV Analysis for Determining the Locus of Synaptic Plasticity
Frontiers in Synaptic Neuroscience, 2020 Long-term synaptic plasticity is widely believed to underlie learning and memory in the brain. Whether plasticity is primarily expressed pre- or postsynaptically has been the subject of considerable debate for many decades. More recently, it is generally
Jennifer A. Brock +6 more
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Frontiers in Synaptic Neuroscience, 2021 Neuromodulation can profoundly impact the gain and polarity of postsynaptic changes in Hebbian synaptic plasticity. An emerging pattern observed in multiple central synapses is a pull–push type of control in which activation of receptors coupled to the G-
Stefan Mihalas +5 more
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Multiple forms of metaplasticity at a single hippocampal synapse during late postnatal development
Developmental Cognitive Neuroscience, 2015 Metaplasticity refers to adjustment in the requirements for induction of synaptic plasticity based on the prior history of activity. Numerous forms of developmental metaplasticity are observed at Schaffer collateral synapses in the rat hippocampus at the
Daniel G. McHail, Theodore C. Dumas
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Reversing cerebellar long-term depression [PDF]
Proceedings of the National Academy of Sciences, 2003 The discovery of a postsynaptically expressed form of cerebellar parallel fiber–Purkinje cell long-term potentiation (LTP) raises the question whether this is the long-sought resetting mechanism for long-term depression (LTD). Extracellular monitoring of PC spikes enables stable prolonged recordings of parallel fiber–Purkinje cell synaptic
Varda Lev-Ram +3 more
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