Results 291 to 300 of about 4,590,611 (322)

The long-term management of depression

Journal of Psychopharmacology, 1995
The long-term outlook for patients with unipolar depression is often poor. As few as one-fifth will remain well and a similar number will suffer chronic depression. It is now standard practice to extend acute treatment into a 4–6 month period of continuation therapy, and the value of prophylactic treatment over longer periods is becoming more widely ...
openaire   +2 more sources

Involvement of a calcineurin/ inhibitor-1 phosphatase cascade in hippocampal long-term depression

Nature, 1994
R. Mulkey, S. Endo, S. Shenolikar, R. Malenka   +3 more
semanticscholar   +1 more source

Role for rapid dendritic protein synthesis in hippocampal mGluR-dependent long-term depression.

Science, 2000
K. Huber, M. Kayser, M. Bear
semanticscholar   +1 more source

Long-Term Potentiation and Long-Term Depression

Synaptic plasticity, the ability of chemical synapses to strengthen or weaken, has long been postulated to be a mechanistic basis of memory. Long-term potentiation (LTP), one form of synaptic plasticity, is defined as a persistent increase in the strength of synaptic transmission, whereas long-term depression (LTD) is the opposite—a persistent decrease
openaire   +1 more source

Long-term Depression

2006
  +4 more sources

Cerebellar long-term depression: characterization, signal transduction, and functional roles.

Physiological Reviews, 2001
Masao Ito
semanticscholar   +1 more source

Mechanisms underlying induction of homosynaptic long-term depression in area CA1 of the hippocampus

Neuron, 1992
R. Mulkey, R. Malenka
semanticscholar   +1 more source

Activation of p75NTR by proBDNF facilitates hippocampal long-term depression

Nature Neuroscience, 2005
N. Woo, Henry K Teng, C. Siao, C. Chiaruttini, Petti T. Pang, T. Milner, B. Hempstead, B. Lu   +7 more
semanticscholar   +1 more source

Different voltage-dependent thresholds for inducing long-term depression and long-term potentiation in slices of rat visual cortex

Nature, 1990
A. Artola, S. Brocher, W. Singer
semanticscholar   +1 more source

Long-Term Depression

2010
Gabriele Fischer, Annemarie Unger, W. Wolfgang Fleischhacker, Cécile Viollet, Jacques Epelbaum, Daniel Hoyer, Ina Weiner, Ian Hindmarch, Martina de Zwaan, Joseph H. Friedman, David A. Brent, Fadi T. Maalouf, Paul Willner, Francis C. Colpaert, Eric J. Nestler, David S. Tait, Verity J. Brown, Malcolm Lader, Tooru M. Mizuno, Paolo Nencini, Michele S. Milella, Daniel Hoyer, W. Wolfgang Fleischhacker, Stephen B. Dunnett, Paul Newhouse, Heather Wilkins, Kim Wolff, Alyson J. Bond, Angus Mackay, Sarah Morgan, James Winslow, Jason C. G. Halford, Gorkem Yararbas, Sakire Pogun, Tayfun Uzbay, Lisiane Bizarro, Martine Cador, Roshan Cools, Dietrich van Calker, Anne Berghöfer, Ben J. Harrison, Christos Pantelis, Lawrence H. Price, Ian P. Stolerman, Gorkem Yararbas, Sakire Pogun, Anthony L. Riley, Steve Kohut, Andreas Marneros, Helen E. Gibson, Susan Jones, Iván Izquierdo, Lia R. Bevilaqua, Martin Cammarota, Elizabeth C. Warburton, Elizabeth C. Warburton, Malcolm Lader, Lance R. McMahon, Lance R. McMahon   +58 more
openaire   +1 more source