Results 301 to 310 of about 4,235,672 (400)

Recognising anxiety and depression in patients with long-term physical conditions [PDF]

, 2020
Chelvanayagam, Sonya, Eales, Sarah, Tuck, Josie   +2 more
core  

The Locus Coeruleus‐Periaqueductal Gray GABAergic Projection Regulates Comorbid Pain and Depression

Advanced Science, EarlyView.
LC‐GABA neurons exhibit elevated activity to noxious and aversive stimuli in chronic pain, and their activation alleviates pain‐ and depression‐like behaviors. While LC‐GABA neurons target LC‐NA neurons and GABA and Glu neurons in the vlPAG, they modulate the pain responses of LC‐NA neurons but regulate pain‐ and depression‐like behaviors through their
Yuan Gao, Xue Zhang, Xiao‐Juan Liu, Yi‐Ling Sun, Cui Yin, Dong‐Liang Tang, Cheng Xiao, Chunyi Zhou   +7 more
wiley   +1 more source

Fear conditioning and extinction distinctively alter bidirectional synaptic plasticity within the amygdala of an animal model of post-traumatic stress disorder

Neurobiology of Stress
Synaptic plasticity in the amygdala plays an essential role in the formation and inhibition of fear memory; however, this plasticity has mainly been studied in the lateral amygdala, making it largely uninvestigated in other subnuclei.
Kwanghoon Park, Hoyong Park, ChiHye Chung   +2 more
doaj  

Impairment of Eyeblink Conditioning and Lack of Long Term Depression in Rostral Cerebellum in Phospholipase C beta4 Deficient Mice

, 2000
Masahiro Kishio, Moritoshi Hirono, Takashi Sugiyama, Yasushi Kishimoto, Takahito Miyazawa, S. Kawahara, Yutaka Kirino, Masato Katsuki, Tohru Yoshioka   +8 more
openalex   +2 more sources

The Maudsley long-term follow-up of child and adolescent depression [PDF]

, 2002
Martín Knapp, Paul McCrone, Éric Fombonne, Jennifer Beecham, Gail Wostear   +4 more
openalex   +1 more source

Presynaptic long-term depression mediated by Gi/o-coupled receptors

Trends in Neurosciences, 2014
Brady K. Atwood, D. Lovinger, B. Mathur
semanticscholar   +1 more source

Functionalized Biomimetic Nanoparticles Targeting the IL‐10/IL‐10Rα/Glycolytic Axis in Synovial Macrophages Alleviate Cartilage Degeneration in Osteoarthritis

Advanced Science, EarlyView.
The MOF material UIO‐66‐NH2 is functionalized with DBCO groups on its surface, encapsulating NO‐prednisolone and conjugating it with azide‐modified IL‐10. Finally, the complex is extruded with MM to form biomimetic functional nanoparticles. Upon intra‐articular injection, MI@UN, enveloped by the MM, specifically targets synovial macrophages, is ...
Wenwei Li, Yang Liu, Ming Wei, Zhichao Yang, Zhaoyu Li, Zezhong Guo, Liang Yan, Yang Lu, Hao Tang, Bofeng Li, Wei Huang   +10 more
wiley   +1 more source

Layer-specific serotonergic induction of long-term depression in the prefrontal cortex of rats. [PDF]

Korean J Physiol Pharmacol, 2020
Shin D, Cho KH, Joo K, Rhie DJ.
europepmc   +1 more source

Modulation of Presynaptic Calcium Transients by Metabotropic Glutamate Receptor Activation: A Differential Role in Acute Depression of Synaptic Transmission and Long-Term Depression [PDF]

, 2002
Guido C. Faas, Hita Adwanikar, Robert W. Gereau, Peter Saggau   +3 more
openalex   +1 more source

Electric Field‐Driven Conformational Changes in Molecular Memristor and Synaptic Behavior

Advanced Science, EarlyView.
Self‐assembled monolayers (SAMs) based molecular device is used for the emulation of synaptic functions. The device operates with a novel switching mechanism via incoherent charge transport, inducing conformational changes. With a low energy consumption (8.0 pJ µm−2), the system shows promise for neuromorphic computing, offering potential in low‐energy,
Chanjin Lim, Taegil Kim, YoungJu Park, Daeho Kim, ChaeHo Shin, Suji Ha, Jin‐Liang Lin, Yuan Li, Junwoo Park   +8 more
wiley   +1 more source