Results 61 to 70 of about 4,459,968 (325)

The economic impact of COVID-19 on the EU: From the frying pan into the fire. EPC Discussion Paper 23 April 2020 [PDF]

, 2020
For the time being, the health impact of the COVID-19 pandemic will, for obvious reasons related to the devastating effects of the virus, continue to be at the forefront of public policy.
Zuleeg, Fabian
core  

Early clinical predictors and correlates of long-term morbidity in bipolar disorder [PDF]

, 2017
OBJECTIVES: Identifying factors predictive of long-term morbidity should improve clinical planning limiting disability and mortality associated with bipolar disorder (BD).
Baldessarini, R. J., DE CHIARA, Lavinia, Girardi, Paolo, Koukopoulos, A. E., Koukopoulos, Alexia, Reginaldi, D., Sani, Gabriele, Serra, Giulia, Tondo, L.   +8 more
core   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

TIME OF DIABETIC ULCER FOOT SUFFERING AND DEPRESSION SYMPTOMS IN ULIN GENERAL HOSPITAL BANJARMASIN

Berkala Kedokteran, 2017
: Diabetic foot ulcers are one kind of chronic complication of diabetes mellitus in the form of an open wound on the skin’s surface and may be accompanied by local tissue death.  Long term suffering of diabetic foot ulcers with physical and psychological
Rizka Dwi Puteri, Yulizar Darwis, Farida Heriyani   +2 more
doaj   +1 more source

Endoscopic findings and psychometric abnormalities: what is the relationship in upper endoscopic outpatients? [PDF]

, 2015
Background. Psychological disorders are often associated with diseases of the upper digestive tract. Although emotions can influence gastrointestinal function in healthy individuals, psychological setting in upper gastrointestinal patients are unclear ...
ANGELINI, Rita, FILIPPINI, Angelo, MARIANETTI, Massimo, MINA, Concetta, PETRARCA, LAURA, PONTONE, Paolo, PONTONE, Stefano, RIDOLA, LORENZO, STANDOLI, MONICA   +8 more
core   +1 more source

Molecular determinants of signal transduction in tropomyosin receptor kinases

FEBS Open Bio, EarlyView.
Tropomyosin receptor kinases control critical neuronal functions, but how do the same receptors produce diverse cellular responses? This review explores the structural mechanisms behind Trk signaling diversity, focusing on allosteric modulation and ligand bias.
Giray Enkavi
wiley   +1 more source

Sexual Dimorphism of Synaptic Plasticity Changes in CA1 Hippocampal Networks in Hypergravity-Exposed Mice—New Insights for Cognition in Space

Cells
Background: We recently reported sex-dependent impairment in cognitive functions in male and female mice exposed for 24 h, 48 h or 15 days to 2G hypergravity (HG).
Mathilde Wullen, Valentine Bouet, Thomas Freret, Jean-Marie Billard   +3 more
doaj   +1 more source

Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

Frontiers in Pharmacology, 2019
Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic transmission represent the principal experimental models underlying learning and memory.
Dalila Mango, Amira Saidi, Giusy Ylenia Cisale, Marco Feligioni, Marco Feligioni, Massimo Corbo, Robert Nisticò, Robert Nisticò   +7 more
doaj   +1 more source

Effectiveness of cognitive-behavioural therapy on glycaemic control and psychological outcomes in adults with diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials [PDF]

, 2016
Aim Diabetes is a chronic progressive condition presenting physical, social and psychological challenges that increase the risk of comorbid mental health problems. Cognitive–behavioural therapy (CBT) is effective in treating a variety of psychological
Alam, Ali, Amsberg, Anderson, Andrews, Balhara, Barnard, Bastelaar, Beltman, Bergström, Borkovec, Butler, Chen, Chew, Cohen, Davazdahemamy, Davazdahemamy, Duval, Elliott, Fairburn, Fisher, Gois, Gois, Granath, Grigsby, Henry, Higgins, Hofmann, Ismail, Katon, Kiropoulos, Kroenke, Llorente, Lustman, National Institute for Health and Care Excellence (NICE), Paschalides, Penckofer, Piette, Polit, Safren, Simon, Simos, Snoek, Snoek, Snoek, Turner, Ven, Wampold, Wang, Weinger, Welschen, Welschen, Westbrook, Winkley   +53 more
core   +1 more source

miR-191 and miR-135 are required for long-lasting spine remodeling associated with synaptic long term depression

Nature Communications, 2014
Activity-dependent modification of dendritic spines, subcellular compartments accommodating postsynaptic specializations in the brain, is an important cellular mechanism for brain development, cognition and synaptic pathology of brain disorders.
Zhonghua Hu, Danni Yu, Qinhua Gu, Yanqin Yang, K. Tu, Jun Zhu, Zheng Li   +6 more
semanticscholar   +1 more source