Results 61 to 70 of about 4,590,611 (322)

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Sexual Dimorphism of Synaptic Plasticity Changes in CA1 Hippocampal Networks in Hypergravity-Exposed Mice—New Insights for Cognition in Space

Cells
Background: We recently reported sex-dependent impairment in cognitive functions in male and female mice exposed for 24 h, 48 h or 15 days to 2G hypergravity (HG).
Mathilde Wullen, Valentine Bouet, Thomas Freret, Jean-Marie Billard   +3 more
doaj   +1 more source

Targeting Synaptic Plasticity in Experimental Models of Alzheimer’s Disease

Frontiers in Pharmacology, 2019
Long-term potentiation (LTP) and long-term depression (LTD) of hippocampal synaptic transmission represent the principal experimental models underlying learning and memory.
Dalila Mango, Amira Saidi, Giusy Ylenia Cisale, Marco Feligioni, Marco Feligioni, Massimo Corbo, Robert Nisticò, Robert Nisticò   +7 more
doaj   +1 more source

Input-specific maturation of synaptic dynamics of parvalbumin interneurons in primary visual cortex [PDF]

, 2014
Cortical networks consist of local recurrent circuits and long-range pathways from other brain areas. Parvalbumin-positive interneurons (PVNs) regulate the dynamic operation of local ensembles as well as the temporal precision of afferent signals.
Huang, Z. J., Lin, Y., Lu, J., Tucciarone, J.   +3 more
core   +1 more source

Developmental Disorders in Children Recently Diagnosed With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Neurocognitive deficits in adult survivors of childhood cancer are well established, but less is known about developmental disorders (DD) arising shortly after cancer diagnosis. Using 2016–2019 linked Ohio cancer registry and Medicaid data, we compared DD among 324 children with cancer and 606,913 cancer‐free controls.
Jamie Shoag, Long Vu, Ritika Miryala, Jeffrey M. Albert, Molly McVoy, Siran M. Koroukian   +5 more
wiley   +1 more source

The role of astrocytic aquaporin-4 in synaptic plasticity and learning and memory

Frontiers in Integrative Neuroscience, 2016
Aquaporin-4 (AQP4) is the predominant water channel expressed by astrocytes in the central nervous system. AQP4 is widely expressed throughout the brain, especially at the blood-brain barrier where AQP4 is highly polarized to astrocytic foot processes ...
Jenny I. Szu, Devin K. Binder
doaj   +1 more source

Microtubule-associated protein tau is essential for long-term depression in the hippocampus

Philosophical Transactions of the Royal Society B: Biological Sciences, 2014
The microtubule-associated protein tau is a principal component of neurofibrillary tangles, and has been identified as a key molecule in Alzheimer's disease and other tauopathies. However, it is unknown how a protein that is primarily located in axons is
Tetsuya Kimura, Daniel J. Whitcomb, J. Jo, P. Regan, T. Piers, S. Heo, Christopher Brown, T. Hashikawa, M. Murayama, H. Seok, I. Sotiropoulos, Eunjoon Kim, G. Collingridge, A. Takashima, Kwangwook Cho   +14 more
semanticscholar   +1 more source

Peer Rejection and Friendships in Children with Attention-Deficit/Hyperactivity Disorder: Contributions to Long-Term Outcomes [PDF]

, 2012
Even after evidence-based treatment, Attention- Deficit/Hyperactivity Disorder (ADHD) is associated with poor long-term outcomes. These outcomes may be partly explained by difficulties in peer functioning, which are common among children with ADHD and ...
Arnold, L. Eugene, Gerdes, Alyson C., Hechtman, Lily, Hinshaw, Stephen P., Hoza, Betsy, Molina, Brooke S. G., Mrug, Sylvie   +6 more
core   +2 more sources

Characterizing Parental Concerns About Lasting Impacts of Treatment in Children With B‐Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background B‐acute lymphoblastic leukemia (B‐ALL) is the most common pediatric cancer, and while most children in high‐resource settings are cured, therapy carries risks for long‐term toxicities. Understanding parents’ concerns about these late effects is essential to guide anticipatory support and inform evolving therapeutic approaches ...
Kellee N. Parker, Sarah W. Alexander, Lisa M. Jacola, Kimberly A. Buff, Kyobin Hwang, Elham Hashemi, Gregory Stoddard, Lindsay A. Jibb   +7 more
wiley   +1 more source

TIME OF DIABETIC ULCER FOOT SUFFERING AND DEPRESSION SYMPTOMS IN ULIN GENERAL HOSPITAL BANJARMASIN

Berkala Kedokteran, 2017
: Diabetic foot ulcers are one kind of chronic complication of diabetes mellitus in the form of an open wound on the skin’s surface and may be accompanied by local tissue death.  Long term suffering of diabetic foot ulcers with physical and psychological
Rizka Dwi Puteri, Yulizar Darwis, Farida Heriyani   +2 more
doaj   +1 more source