Results 71 to 80 of about 476,218 (260)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

A Long-Term Assessment of Nitrogen Removal Performance and Microecosystem Evolution in Bioretention Columns Modified with Sponge Iron

Toxics
The nitrogen removal performance of bioretention urgently needs to be improved, and sponge iron has great potential to address this challenge. This study reported the results of a long-term investigation on bioretention columns improved by sponge iron ...
Zizeng Lin, Qinghuan Shi, Qiumei He
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A new methodology to identify Structures, Systems, and Components needed to cope with Design Extended Conditions in the scope of a Nuclear Power Plant Long Term Operation

Brazilian Journal of Radiation Sciences
To obtain the License Renewal (LR) for the Long-Term Operation (LTO) of a Nuclear Power Plants (NPPs) is important ensuring the integrity of Structures, Systems, and Components (SSCs).
Maritza Rodríguez Gual, Jorge Armando P. Junior   +1 more
doaj   +1 more source

Upscaled production of an ultramicroporous anion-exchange membrane enables long-term operation in electrochemical energy devices. [PDF]

Nat Commun, 2023
Song W, Peng K, Xu W, Liu X, Zhang H, Liang X, Ye B, Zhang H, Yang Z, Wu L, Ge X, Xu T.   +11 more
europepmc   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Adapting reservoir operation to climate change in regions with long-term hydrologic persistence

Climate Risk Management
Large-scale climate variability patterns such as El Niño-Southern Oscillation (ENSO) influence the hydrology and hence affect the management of water resources in numerous regions around the globe.
Vahid Espanmanesh, Etienne Guilpart, Marc-André Bourgault, Amaury Tilmant   +3 more
doaj   +1 more source

Author Correction: Upscaled production of an ultramicroporous anion-exchange membrane enables long-term operation in electrochemical energy devices. [PDF]

Nat Commun, 2023
Song W, Peng K, Xu W, Liu X, Zhang H, Liang X, Ye B, Zhang H, Yang Z, Wu L, Ge X, Xu T.   +11 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A New Reactor Concept for Single-Chamber Microbial Fuel Cells and Possible Anti-Fouling Strategies for Long-Term Operation. [PDF]

Microorganisms, 2022
Haupt DR, Landwehr L, Schumann R, Hahn L, Issa M, Coskun C, Kunz U, Sievers M.   +7 more
europepmc   +1 more source