Results 61 to 70 of about 20,310,635 (136)
Genomic and transcriptional co-localization of protein-coding and long non-coding RNA pairs in the developing brain. [PDF]
, 2009 Besides protein-coding mRNAs, eukaryotic transcriptomes include many long non-protein-coding RNAs (ncRNAs) of unknown function that are transcribed away from protein-coding loci. Here, we have identified 659 intergenic long ncRNAs whose genomic sequences
Peter L Oliver +7 more
core +1 more source
Long Non-Coding RNA Function in CD4+ T Cells: What We Know and What Next? [PDF]
, 2019 The non-coding genome has previously been regarded as "junk" DNA; however, emerging evidence suggests that the non-coding genome accounts for some of the greater biological complexity observed in mammals.
Lagos, Dimitris +5 more
core +1 more source
, 2016 The abundance of mammalian long intergenic non-coding RNA (lincRNA) genes is high, yet their functions remain largely unknown. One possible way to study this important question is to use large-scale comparisons of various characteristics of lincRNA with ...
Galina V. Glazko +6 more
core +1 more source
More than the SRY: The Non-Coding Landscape of the Y Chromosome and Its Importance in Human Disease
Historically, the Y chromosome has presented challenges to classical methodology and philosophy of understanding the differences between males and females. A genetic unsolved puzzle, the Y chromosome was the last chromosome to be fully sequenced.
Ivan Martinez +3 more
core +1 more source
Z Probe, An Efficient Tool for Characterizing Long Non-Coding RNA in FFPE Tissues
, 2018 Formalin-fixed paraffin embedded (FFPE) tissues are a valuable resource for biomarker discovery in order to understand the etiology of different cancers and many other diseases.
Murali M. Yallapu +10 more
core +1 more source
The Role of Long Non-Coding RNAs in Osteosarcoma
, 2018 Long non-coding RNAs (lncRNAs) constitute non-protein coding transcripts with a size > than 200 nucleotides. They are involved in many cellular processes, such as chromatin remodelling, transcription, and gene expression.
Martin Pichler +2 more
core +1 more source
Neuroblastoma is the commonest solid tumour in early childhood. Survivors suffer from lifelong disabilities due to chemotherapy. In this application, we will define the role of gene amplification of a long intergenic non-protein-coding RNA in determining
core
Effect of Non-Coding RNA on Post-Transcriptional Gene Silencing of Alzheimer Disease [PDF]
, 2010 A large amount of hidden biological information is contained in the human genome, which is not expressed or revealed in the form of proteins; the usual end product form of gene expression.
Premkumar P +7 more
core
The Role of Long Non-Coding RNAs in Human Endoderm Differentiation
The human genome sequencing revealed a vast complexity of transcripts, with over 80% of the genome being transcribed into non-coding RNAs. In particular, long non-coding RNAs (lncRNAs) have emerged as critical regulators of various cellular processes ...
Bruno Dallagiovanna +1 more
core +1 more source