Results 1 to 10 of about 116,033,210 (184)

ETS proto-oncogene 1 modulates PTP1B expression to participate in high glucose-mediated endothelial inflammation [PDF]

Acta Biochimica et Biophysica Sinica, 2022
Hyperglycemia-induced endothelial inflammation participates in the pathogenesis of cardiovascular complications in diabetics. Previous studies showed that protein tyrosine phosphatase 1B (PTP1B) and ETS proto-oncogene 1 (ets1) are involved in ...
Jiang Lili, Liang Jincai, Wang Tianhai, Meng Fufen, Duan Wenming   +4 more
doaj   +5 more sources

Transcription Factor ETS Proto-Oncogene 1 Contributes to Neuropathic Pain by Regulating Histone Deacetylase 1 in Primary Afferent Neurons [PDF]

Molecular Pain, 2023
Nerve injury can induce aberrant changes in ion channels, enzymes, and cytokines/chemokines in the dorsal root ganglia (DRGs); these changes are due to or at least partly governed by transcription factors that contribute to the genesis of neuropathic ...
Zhiqiang Pan, Runa Wei, Kehui Yang
exaly   +5 more sources

ETS Proto-Oncogene 1-Activated Muskelin 1 Antisense RNA Drives the Malignant Progression of Hepatocellular Carcinoma by Targeting miR-22-3p to Upregulate ETS Proto-Oncogene 1 [PDF]

Bioengineered, 2022
Long noncoding RNA muskelin 1 antisense RNA (MKLN1-AS) acted as an oncogenic regulator in hepatocellular carcinoma (HCC). This study was performed to investigate the functional mechanism of MKLN1-AS. MKLN1-AS, microRNA-22-3p (miR-22-3p) and ETS Proto-Oncogene 1 (ETS1) levels were examined using reverse transcription-quantitative polymerase-chain ...
Shuling Wang
exaly   +6 more sources

ETS Proto-Oncogene 1 Suppresses MicroRNA-128 Transcription to Promote Osteogenic Differentiation Through the HOXA13/β-Catenin Axis [PDF]

Frontiers in Physiology, 2021
ETS proto-oncogene 1 (ETS1) has been implicated in osteoporosis (OP), but the exact molecular mechanisms are complex. This work focuses on the impact of ETS1 on the osteogenic differentiation and the molecules involved.
Renyao Li, Ying Dong, Feipeng Li
doaj   +5 more sources

The Epigenetic Reader, Bromodomain Containing 2, Mediates Cholangiocyte Senescence via Interaction With ETS Proto-Oncogene 1 [PDF]

Gastroenterology, 2023
We reported that cholangiocyte senescence, regulated by the transcription factor ETS proto-oncogene 1 (ETS1), is a pathogenic feature of primary sclerosing cholangitis (PSC). Furthermore, histone 3 lysine 27 is acetylated at senescence-associated loci.
Jeong-Han Kang, Gregory J Gores, Nicholas D. Larusso   +2 more
exaly   +4 more sources

Neutrophil Extracellular Traps-Mediated Intraplaque Angiogenesis and Microvascular Permeability Promote Rapid Plaque Progression following Myocardial Infarction [PDF]

Research
Despite adherence to guideline-recommended therapies, survivors of myocardial infarction (MI) remain at high risk for recurrent ischemic events. This study aimed to elucidate the underlying mechanisms responsible for this residual risk.
Zhijun Lei, Yunfei Yin, Long Zeng, Na Yang, Ming Zhai, Yanxi Zeng, Yefei Shi, Qing Yu, Shiyu Gong, Weixia Jian, Jianhui Zhuang, Li Zhang, Wenhui Peng   +12 more
doaj   +2 more sources

Expression of the ets-1 proto-oncogene in human breast carcinoma: differential expression with histological grading and growth pattern. [PDF]

Histology and histopathology, 2005
The proto-oncogene, ets-1, is a transcription factor known to control the expression of a number of genes and has been postulated to play a role in cell growth, differentiation and tumour invasion. We examined 137 cases of breast carcinoma by immunohistochemistry and compared the degree of Ets-1 expression among the different histological types of ...
Katayama, S., Nakayama, T., Ito, M., Naito, S., Sekine, I.   +4 more
openaire   +4 more sources

Biopsy of Secondary Angiosarcoma Arising in Native Mastectomy Skin of a Reconstructed Breast Without Prior Radiotherapy [PDF]

Plastic and Reconstructive Surgery, Global Open
Summary:. Secondary breast angiosarcoma usually develops after radiotherapy or in the setting of chronic lymphedema. We report a rare case of non-radiation-associated secondary cutaneous angiosarcoma arising in the native mastectomy skin overlying a ...
Mina Kamegai, MD, Yohei Iwanaga, MD, Shoichi Tomita, MD, PhD, Miwako Fujii, MD, Keisuke Goto, MD, Tsunekazu Hishima, MD, Rei Ogawa, MD, PhD, Yasunobu Terao, MD, PhD   +7 more
doaj   +2 more sources

ETS proto-oncogene 1 transcription factor is differentially expressed in lymph node metastasis in human breast cancer.

, 2021
Metastasis to the brain is a clinical problem in patients with breast cancer (1-3). Between the breast and the brain reside the secondary lymphoid organ, the lymph nodes. We mined published microarray data (4, 5) to compare primary and metastatic tumor transcriptomes for the discovery of genes associated with metastasis to the lymph nodes in humans ...
Shahan Mamoor
openaire   +3 more sources

Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits

, 2022
Supplementary Table from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional ...
Volker Hovestadt (14958848), Xiaolong Chen (14958794), Christof M. Kramm (14958836), Michaela Nathrath (88030), Jayne Vogelzang (14958785), Jeromy J. Digiacomo (14958812), Claudia L. Kleinman (14958851), Henry Long (14958854), Kevin N. Zhou (14958800), Maria Tsoli (14958824), Stefan Bielack (14958839), Xin Wei (119082), Cecilia Sousa (14958788), Sarah E. Dixon-Clarke (5114174), Uta Dirksen (14958827), Frank P.B. Dubois (14958779), Gnana Prakash Balasubramanian (14958833), Smruti Patel (14958770), Elizabeth M. Gonzalez (14958806), Audrey Baguette (14958791), Nada Jabado (4544824), Stefan M. Pfister (14946090), Alexandra L. Condurat (14958797), Jinghui Zhang (8906078), Sudeepa Syamala (14958776), Paloma Cejas (368528), Kristine Pelton (153505), Madison S. Chacon (14958809), Ningxuan Zhou (8066030), Natalie Jager (14958830), Suzanne J. Baker (8756949), Pratiti Bandopadhayay (9683938), David W. Wu (14958773), François Aguet (14958842), Sophie D. Lu (14958803), Rushil Kumbhani (14958815), Gad Getz (14945542), Olaf Witt (1463524), Keith L. Ligon (14958845), David T.W. Jones (14958857), Dayle K. Wang (14958767), Phonepasong Arounleut (445842), Alexander Crane (14958782), Jessica W. Tsai (14958764), David S. Ziegler (3615308), Dana Novikov (14958818), Timothy N. Phoenix (11322350), J'Ya Hunter (14958821), James M. McFarland (14952522)   +48 more
core   +9 more sources