Results 21 to 30 of about 116,033,210 (184)

Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits

open access: yes, 2022
Supplementary Figure from FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional ...
Volker Hovestadt (14958848)   +48 more
core   +5 more sources

Erythropoietin Inhibits Hypoxia–Induced Epithelial-To-Mesenchymal Transition via Upregulation of miR-200b in HK-2 Cells

open access: yesCellular Physiology and Biochemistry, 2017
Background/Aims: Renal tubular epithelial-mesenchymal transition (EMT) is regarded as an important factor leading to renal interstitial fibrosis. Erythropoietin (EPO) has been reported to attenuate renal fibrosis. The mechanism underlying this protective
Jiuxu Bai   +6 more
doaj   +1 more source

Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells [PDF]

open access: yes, 2009
Background Transplantation of vasculogenic progenitor cells (VPC) improves neovascularization after ischemia. However, patients with type 2 diabetes mellitus show a reduced VPC number and impaired functional activity. Previously, we demonstrated that p38
Aicher Alexandra   +17 more
core   +2 more sources

Structural insights into the autoregulation and cooperativity of the human transcription factor Ets-2 [PDF]

open access: yes, 2015
Ets-2, like its closely related homologue Ets-1, is a member of the Ets family of DNA binding transcription factors. Both proteins are subject to multiple levels of regulation of their DNA binding and transactivation properties.
Gileadi, Opher   +3 more
core   +1 more source

ETS-1 oncoprotein expression is decreased in aggressive papillary transitional cell carcinoma of the urinary bladder: An immunohistochemical study

open access: yesAfrican Journal of Urology, 2017
Introduction: ETS-1 proto-oncogene is a transcription factor that plays multiple roles in the process of oncogenesis and helps in the process of tumor invasion.
E.A. Ibrahim, M.R. Hassan, S.A. Sammour
doaj   +1 more source

Downregulation of miRNA-451a Promotes the Differentiation of CD4+ T Cells towards Th2 Cells by Upregulating ETS1 in Childhood Asthma

open access: yesJournal of Innate Immunity, 2020
Children exposed to common aeroallergens may develop asthma that progresses into adulthood. Inflammation regulated by T helper 2 (Th2) cells, a specific subpopulation of CD4+ T lymphocytes, is involved in asthmatic injury.
Tianyue  Wang   +2 more
doaj   +1 more source

LINC00704 contributes to the proliferation and accelerates the cell cycle of nasopharyngeal carcinoma cells via regulating ETS1/CDK6 axis

open access: yesKaohsiung Journal of Medical Sciences, 2022
This study is aimed at exploring the biological functions and related mechanism of long noncoding RNA 704 (LINC00704) in the proliferation and cell cycle progression of nasopharyngeal carcinoma (NPC) cells.
Yan Wang   +6 more
doaj   +1 more source

ETS1 (v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)) [PDF]

open access: yes, 2010
Review on ETS1 (v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)), with data on DNA, on the protein encoded, and where the gene is ...
Lindstrot, A   +5 more
core   +1 more source

SPI1 is a prognostic biomarker of immune infiltration and immunotherapy efficacy in clear cell renal cell carcinoma

open access: yesDiscover Oncology, 2022
Background Spi-1 proto-oncogene (SPI1), which encodes an ETS-domain transcription factor, can activate gene expression in myeloid and lymphoid lineages.
Huayi Feng   +8 more
doaj   +1 more source

MicroRNA-769-5p Inhibits Pancreatic Ductal Adenocarcinoma Progression by Directly Targeting and Downregulating ETS Proto-Oncogene 1.

open access: yesOnco Targets Ther, 2019
MicroRNA-769-5p (miR-769) is aberrantly expressed and plays crucial roles in non-small cell lung cancer and melanoma. However, the expression pattern, biological role, and mechanisms of action of miR-769 in pancreatic ductal adenocarcinoma (PDAC) are yet to be fully elucidated.
Cheng K, Feng L, Yu S, Yu C, Chi N.
europepmc   +4 more sources

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