Inversion of a chicken ets-1 proto-oncogene segment in avian leukemia virus E26 [PDF]
The segment of the avian leukemia virus E26 genome near the termination of the p135gag-myb-ets open reading frame contains an inversion of the chicken ets-1 sequence. The inversion contains at least 41 bp and may be as large as 46 bp. This results in the replacement of 13 amino acids of chicken ets-1, with 16 amino acids derived from reverse complement
J A Lautenberger, Takis S. Papas
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The c-ets-1 proto-oncogene is rearranged in some cases of acute lymphoblastic leukaemia [PDF]
M.H. Goyns +4 more
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Characterization ofXenopus laeviscDNA clones of the c-ets-1proto-oncogene
Patrick Stiegler +9 more
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Expression of the ets-1 proto-oncogene in human breast carcinoma :Differential expression with histological grading and growth pattern [PDF]
The proto-oncogene, ets-1, is a transcription factor known to control the expression of a number of genes and has been postulated to play a role in cell growth, differentiation and tumour invasion. We examined 137 cases of breast carcinoma by immunohistochemistry and compared the degree of Ets-1 expression among the different histological types of ...
明香 片山
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Alternative splicing within the chicken c-ets-1 locus: implications for transduction within the E26 retrovirus of the c-ets proto-oncogene [PDF]
Two overlapping c-ets-1 cDNA clones were isolated which contained the alpha and beta genomic sequences homologous to the 5' end of v-ets not detected in the previously described c-ets RNA species or proteins. Nucleotide sequencing demonstrated that these cDNAs corresponded to the splicing of alpha and beta to a common set of 3' exons (a through F ...
Dominique Leprince +6 more
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Bioinformatics network analyses of growth differentiation factor 11
Growth differentiation factor 11 (GDF11) has been implicated in rejuvenating functions in age-related diseases. The molecular mechanisms connecting GDF11 with these anti-aging phenomena, including reverse age-related cardiac hypertrophy and vascular and ...
Zhang Feng, Yang Xia, Bao Zhijun
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Hypoxia stimulates angiogenesis and a metabolic switch in human parathyroid adenoma cells
Hypoxia, a primary stimulus for angiogenesis, is important for tumour proliferation and survival. The effects of hypoxia on parathyroid tumour cells, which may also be important for parathyroid autotransplantation in patients, are, however, unknown.
K E Lines +8 more
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Renal Expression of the Ets-1 Proto-oncogene during Progression of Rat Crescentic Glomerulonephritis [PDF]
The ets-1 proto-oncogene is a member of the transcriptional factor family and was identified by homology to the v-ets oncogene. It was recently demonstrated that Ets-1 protein interacts with the promoter region of the genes coding for proteinases, including matrix metalloproteinase-1 (MMP-1), MMP-3, and urokinase-type plasminogen activator, suggesting ...
Takashi, Naito +6 more
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Evaluation of effects caused by differentially spliced Ets-1 transcripts in fibroblasts [PDF]
The transcription factor Ets-1 is known to be involved in a broad variety of cellular functions such as cell proliferation, migration, invasion, apoptosis and angiogenesis.
Edwards, Dyaln R. +6 more
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Background/Aims: Renal tubular epithelial-mesenchymal transition (EMT) is regarded as an important factor leading to renal interstitial fibrosis. Erythropoietin (EPO) has been reported to attenuate renal fibrosis. The mechanism underlying this protective
Jiuxu Bai +6 more
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