Results 41 to 50 of about 30,453 (235)

Ets-1 and Ets-2 proto-oncogenes exhibit differential and restricted expression patterns during Xenopus laevis oogenesis and embryogenesis [PDF]

The International journal of developmental biology, 1997
Xenopus XI-ets-1 and XI-ets-2 are maternally expressed. From late oogenesis to early embryogenesis their transcripts are localized to the animal pole and the intermediate zone, suggesting a function in the differentiation of animal blastomeres and future mesoderm.
Denise Meyer, M Durliat, F. Sénan, Michael von Wolff, Michèle André, J. Hourdry, P. Rémy   +6 more
openalex   +3 more sources

ETS-1 oncoprotein expression is decreased in aggressive papillary transitional cell carcinoma of the urinary bladder: An immunohistochemical study

African Journal of Urology, 2017
Introduction: ETS-1 proto-oncogene is a transcription factor that plays multiple roles in the process of oncogenesis and helps in the process of tumor invasion.
E.A. Ibrahim, M.R. Hassan, S.A. Sammour
doaj   +1 more source

Signalling, cell cycle and pluripotency in embryonic stem cells [PDF]

, 2002
International ...
Burdon, Tom, Savatier, Pierre, Smith, Austin   +2 more
core   +1 more source

The molecular basis of T cell acute lymphoblastic leukemia [PDF]

, 2012
T cell acute lymphoblastic leukemias (T-ALLs) arise from the malignant transformation of hematopoietic progenitors primed toward T cell development, as result of a multistep oncogenic process involving constitutive activation of NOTCH signaling and ...
Adolfo Ferrando, Bash, Bash, Chen, Condorelli, Dube, Fisch, Hagemeijer, Hebert, Ho, Kelliher, Kikuchi, Larson, Lu, McGuire, McGuire, Nagel, Ntziachristos, Ntziachristos, Ono, Pieter Van Vlierberghe, Royer-Pokora, Rubnitz, van Grotel   +23 more
core   +1 more source

Mathematical model of a telomerase transcriptional regulatory network developed by cell-based screening: analysis of inhibitor effects and telomerase expression mechanisms [PDF]

, 2014
Cancer cells depend on transcription of telomerase reverse transcriptase (TERT). Many transcription factors affect TERT, though regulation occurs in context of a broader network. Network effects on telomerase regulation have not been investigated, though
A Agrawal, A De Cian, A Goltsov, A Graudenzi, A Schonthal, A Subramanian, A Tapias, A Tapias, A von Kriegsheim, A Wuensche, AE Bilsland, AE Bilsland, AE Bilsland, AE Bilsland, Alan E. Bilsland, B Tang, C Jiang, C Lawless, C Torres-Sosa, CJ Anderson, Claire J. Cairney, D Hanahan, D Machado, D Xu, DE Nelson, DG Johnson, DH Crouch, DJ Billingsley, DL Crowe, DR White, E Yang, EJ Black, F Gizard, FW Huang, G Niu, G Wrobel, H Yuan, J Cho, J Grefenstette, J Won, J Zhao, JN Davis, Jon Roffey, JS Ho, K Cho, K Jiang, K Lafferty-Whyte, K Lafferty-Whyte, K Lafferty-Whyte, K Ookawa, K Thalmeier, K Willadsen, Katrina Stevenson, KI Zeller, KJ Wu, KM Ryan, L Chen, L Durant, L Konnikova, LA Bell, LC Freeman, LE Sivak, LG Wooten-Blanks, LI Chen, M Choi, M Daniel, M Kohl, M Nicolas, M Takakura, N Arkus, N Benson, N Kley, OE Akman, OW Rokhlin, P Angel, PJ Killela, PM Neilsen, Q Wang, R Duan, R Schlatter, R Wilds, RT Sitaram, S Horn, S Hossain, S Huang, S Kauffman, S Kyo, S Mangan, S Oh, Satoru Miyano, SM Mac, SP Hsu, Stacey Hoare, SY Lin, T Kanaya, T Maki-Marttunen, T Sengupta, TG Oliver, TH Kim, U Moehren, V Anest, V Batagelj, VJ Gnanapragasam, VK Mootha, W. Nicol Keith, WB Lee, X Chen, Y Xiao, Y Xing, Y Yao, Yu Liu   +110 more
core   +3 more sources

Disease Progression Mediated by Egr-1 Associated Signaling in Response to Oxidative Stress [PDF]

, 2012
When cellular reducing enzymes fail to shield the cell from increased amounts of reactive oxygen species (ROS), oxidative stress arises. The redox state is misbalanced, DNA and proteins are damaged and cellular transcription networks are activated.
Abdulkadir, Abdulkadir, Aggeli, Arsenian, Banks, Baron, Bedadala, Bedard, Bjelakovic, Bjelakovic, Bonventre, Brand, Calogero, Cao, Cao, Chang, Chen, Christy, Christy, Cramer, Datta, Dixit, Dixit, Dyson, Dyson, Eidelman, Elisabeth Deindl, Eto, Eto, Fahmy, Fahmy, Feldman, Forsberg, Förstermann, Gao, Gashler, Hallahan, Halliwell, Harja, Harman, Harrison, Hasan, Hasan, Hebert, Heo, Hill, Hirata, Huang, Irani, Iyoda, Izumi, Judith-Irina Pagel, Katsarou, Kawamura, Khachigian, Khachigian, Konishi, Lee, Liao, Lim, Lukac, Marais, Meira, Nishi, Nose, Nose, Nozik-Grayck, Ohba, Ouellette, Pagel, Paron, Pavletich, Peskin, Pines, Preston, Radisky, Sakamoto, Sattler, Schwachtgen, Sies, Sies, Stuart, Sudenga, Tell, Tell, Tell, Tell, Terashima, Treisman, Tsai-Morris, Vickers, Vivekananthan, Wang, Whitmarsh, Yan, Yan, Yang, Yang, Ye, Yu   +99 more
core   +2 more sources

Lrf suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion [PDF]

, 2014
Lrf has been previously described as a powerful proto-oncogene. Here we surprisingly demonstrate that Lrf plays a critical oncosuppressive role in the prostate.
Ala, Ugo, Carver, Brett, Chen, Zhenbang, Cordon-Cardo, Carlos, Egia, Ainara, Gerald, William L., Gonzalez-Billalabeitia, Enrique, Kuo, Winston Patrick, Liu, Xue-Song, Lunardi, Andrea, Nardella, Caterina, Pandolfi, Pier Paolo, Shaffer, David R., Signoretti, Sabina, Taulli, Riccardo, Tay, Yvonne, Wang, Guocan, Webster, Kaitlyn A., Zhang, Jiangwen   +18 more
core   +1 more source

A global view of the oncogenic landscape in nasopharyngeal carcinoma : an integrated analysis at the genetic and expression levels [PDF]

, 2012
Previous studies have reported that the tumour cells of nasopharyngeal carcinoma (NPC) exhibit recurrent chromosome abnormalities. These genetic changes are broadly assumed to lead to changes in gene expression which are important for the pathogenesis of
Amari, Aicha, Arrand, J. R. (John R.), Bell, Andrew I., Chen, Xiaoyi, Dawson, Christopher W., Derkaoui, K. Dalia, Hu, Chunfang, Joab, Irène, Maloney, Stephanie L., Murray, Paul G., Nicholls, J. M. (John M.), Shao, Jian-Yong, Sihota, Sim K., Wei, Wenbin, Woodman, Ciaran B. J., Yao, Yunhong, Young, Lawrence S.   +16 more
core   +4 more sources

SPI1 is a prognostic biomarker of immune infiltration and immunotherapy efficacy in clear cell renal cell carcinoma

Discover Oncology, 2022
Background Spi-1 proto-oncogene (SPI1), which encodes an ETS-domain transcription factor, can activate gene expression in myeloid and lymphoid lineages.
Huayi Feng, Tao Wang, Jiali Ye, Yang Yang, Xing Huang, Dong Lai, Zheng Lv, Yan Huang, Xu Zhang   +8 more
doaj   +1 more source

ETS1 acts as a regulator of human healthy aging via decreasing ribosomal activity

Science Advances, 2022
Adaptation to reduced energy production during aging is a fundamental issue for maintaining healthspan or prolonging life span. Currently, however, the underlying mechanism in long-lived people remains poorly understood.
Fu-Hui Xiao, Qin Yu, Z. Deng, Ke Yang, Yunshuang Ye, Mingxia Ge, Dongjing Yan, Hao-Tian Wang, Xiao-Qiong Chen, Li-qin Yang, Bin-Yu Yang, R. Lin, Wen Zhang, Xing-Li Yang, Lei Dong, Yonghan He, Jumin Zhou, Wang-Wei Cai, Ji Li, Q. Kong   +19 more
semanticscholar   +1 more source