Results 91 to 100 of about 9,101,712 (212)

Additional file 8: Figure S5. of Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

, 2016
Statistical comparison of data shown in Fig. 5. Mann-Whitney U-test was used for each comparison and p-values are shown. (PPTX 161 kb)
Kaneko, Mami, Kotake, Masanori, Bando, Hiroyuki, Yamada, Tetsuji, Takemura, Hirofumi, Minamoto, Toshinari   +5 more
openaire   +1 more source

Comparative genomics reveals lineage‐associated structural variation and diversification in a barley fungal pathogen

New Phytologist, EarlyView.
Genome‐wide copy‐number variation landscape highlights structural divergence across Puccinia hordei isolates and potentially links Cyp51 amplification to fungicide insensitivity. Summary Leaf rust, caused by Puccinia hordei, is a major barley disease worldwide.
Xiaohui Yu, Mumta Chhetri, Mafruha Hasan, Thomas H. Roberts, Peng Zhang, Robert F. Park, Yi Ding   +6 more
wiley   +1 more source

HvPHO1 Controls a Glucose 1‐Phosphate–SnRK1 Signalling Module That Coordinates Starch Accumulation in Barley Endosperm

Plant Biotechnology Journal, EarlyView.
ABSTRACT Developing barley grains must balance the use of imported sucrose between soluble sugars and storage starch, but how this balance is controlled remains unclear. Here we show that loss of the plastidial α‐glucan phosphorylase HvPHO1 causes starch and soluble sugars to accumulate concurrently in barley grains.
Yulong Li, Yujia Chen, Jing Liu, Ping Yang, Guangqi Gao, Carlos Guzmán, Qiang Xu, Yazhou Zhang, Yanlin Liu, Pengfei Qi, Mei Deng, Shoufen Dai, Jian Ma, Guoyue Chen, Jirui Wang, Youliang Zheng, Yuming Wei, Qiantao Jiang   +17 more
wiley   +1 more source

Human‐derived cardiac‐neural microtissues reveal catecholaminergic polymorphic ventricular tachycardia is also a disease of the sympathetic neuron

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic diagram illustrating the proposed pathway in which regulatory defects might occur in sympathetic neurons derived from hiPSC in catecholaminergic polymorphic ventricular tachycardia (CPVT). Specifically, enhanced calcium transients appeared to derive from three sources: enhanced membrane excitability (due to loss of ...
Ni Li, Chenchen Zhang, Mengying Xu, YoonYoung Choi, Davi Sidarta‐Oliveira, Ruirui Dong, Xinyu Hu, Enrique M. Toledo, Cesar A. Prada‐Medina, Finbar Argus, Kun Liu, Mingyu Li, Linna Zhou, Hagan Bayley, Corey Smith, Chris Denning, Ana I. Domingos, Guoliang Hao, Dan Li, David J. Paterson   +19 more
wiley   +1 more source

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

Pediatric Blood &Cancer, Volume 73, Issue 11, November 2026.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan, Mariah Wright‐Nadkarni, Mohamed S. Abdelbaki, Girish Dhall   +3 more
wiley   +1 more source

Long interspersed nuclear elements safeguard neural progenitors from precocious differentiation

Summary: Long interspersed nuclear element-1 (L1 or LINE-1) is a highly abundant mobile genetic element in both humans and mice, comprising almost 20% of each genome.
Yoon, H., Emelia Suljic, Suljic, E., Aidan H. McDonald, Michael S. Cuoco, Christina Lim, Fred H. Gage, Hyojung Yoon, Abed AlFatah Mansour, Sarah L. Parylak, Monique Pena, Toda, T., Iryna S. Gallina, McDonald, A., Lisa Mitchell, Mark E. Hester, Schafer, S., Gage, F., Mitchell, L., AlFatah Mansour, A., Tracy A. Bedrosian, Ghassemzadeh, S., Saeed Ghassemzadeh, Boulard, M., Nicole Novaresi, Tomohisa Toda, Pena, M., Novaresi, N., Simon T. Schafer, Sara B. Linker, Lim, C., Gallina, I., Hester, M., Whiteley, J., Cuoco, M., Linker, S., Matthieu Boulard, Bedrosian, T., Jack T. Whiteley, Parylak, S.   +39 more
core   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, Volume 73, Issue 10, October 2026.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

The SIDER2 elements, interspersed repeated sequences that populate the genomes, constitute subfamilies showing chromosomal proximity relationship-2

, 2011
Ong the indicated LiSIDER2s sequences were obtained using the BLAST two sequences tool available at the NCBI Web Page [45]. The retrieved matches are depicted by coloured boxes. (B) The 556-nucleotide long consensus sequence was derived from the ClustalW
Manuel C López (82526), M Carmen Thomas (82527), Jose M Requena (82524), Cristina Folgueira (82525)   +3 more
core   +1 more source

A Bacillus Phage From Bangladeshi Soil, Phage APU1: Genomic Characterisation and Comparative Genomic Analysis

Environmental Microbiology Reports, Volume 18, Issue 5, October 2026.
Phage APU1, isolated from Bangladeshi agricultural soil, is a high‐quality, computationally predicted lytic Bacillus phage with a 153,847‐bp genome and no detected antimicrobial resistance or virulence factor genes. Comparative genomics identified APU1 as a genomically distinct member of a related Bacillus phage group.
Arefeen Haider, Tasnuva Jahan Esha, Sezanur Rahman, Jannat Akther, Naimul Islam Faysal, Tahsin Khan, Shakhinur Islam Mondal, Anowara Begum, Sudhangshu Kumar Biswas, Mustafizur Rahman, Mohammad Jubair   +10 more
wiley   +1 more source

The SIDER2 elements, interspersed repeated sequences that populate the genomes, constitute subfamilies showing chromosomal proximity relationship-7

, 2011
Ong the indicated LiSIDER2s sequences were obtained using the BLAST two sequences tool available at the NCBI Web Page [45]. The retrieved matches are depicted by coloured boxes. (B) The 556-nucleotide long consensus sequence was derived from the ClustalW
Manuel C López (82526), M Carmen Thomas (82527), Jose M Requena (82524), Cristina Folgueira (82525)   +3 more
core   +1 more source