Results 61 to 70 of about 16,187 (162)

Integration of epigenetics into ecotoxicology: insights and fundamental research needs

Biological Reviews, Volume 101, Issue 2, Page 826-847, April 2026.
ABSTRACT Epigenetics refers to heritable changes in genome function that occur without direct alterations to the DNA sequence. A multitude of environmental contaminants can influence the epigenetic marks of a genome. Changes of epigenetic marks including DNA methylation, histone modifications, and non‐coding RNAs can induce alterations at the gene ...
Albano Pinto, Jana Asselman, Patrícia Pereira, Joana Luísa Pereira   +3 more
wiley   +1 more source

Additional file 1: Table S1. of Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

, 2016
Primers and probes used for MethyLight assay, methylation-specific real-time PCR and FAIRE analysis of LINE-1. (DOCX 17 kb)
Kaneko, Mami, Kotake, Masanori, Bando, Hiroyuki, Yamada, Tetsuji, Takemura, Hirofumi, Toshinari Minamoto   +5 more
openaire   +1 more source

Transposable elements: Functional aspects and applications as drivers of crop innovation

Crop Science, Volume 66, Issue 2, March/April 2026.
Abstract Transposable elements (TEs), which were once relegated to the status of genomic parasites, are today accepted as important agents of plant genome evolution and adaptation. This review integrates evidence pointing to their dual function as drivers of genetic diversity and instability, with a focus on their contribution to phenotypic innovation,
Flávia Layse Belém Medeiros, José Ribamar Costa Ferreira‐Neto, Jarbson Henrique Oliveira Silva, Cinthia Carla Claudino Grangeiro Nunes, Ana Luíza Trajano Mangueira de Melo, Ayug Bezerra Lemos, Madson Allan de Luna‐Aragão, Agnes Angélica Guedes de Barros, Simon Orozco‐Arias, Eliseu Binneck, Francismar Correa Marcelino‐Guimarães, Ana Cristina Brasileiro‐Vidal, Ana Maria Benko‐Iseppon   +12 more
wiley   +1 more source

PhyloRef: A Semi‐Automated Workflow for eDNA Reference Database Curation via Phylogenetic Anomaly Detection

Ecology and Evolution, Volume 16, Issue 3, March 2026.
PhyloRef processes complete mitochondrial genomes with optional multi‐gene concatenation to flag three categories of phylogenetic anomalies based on tree topology and annotates ambiguous sequences with “similar_to=” labels. The workflow successfully curated 7600+ chondrichthyan and actinopterygian sequences from NCBI, identifying and removing 410 ...
Yan Mai, Chenhong Li
wiley   +1 more source

Additional file 3: Figure S2. of Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

, 2016
(A) Distribution of LINE-1 methylation level measured by using the primer set (2) (Additional file 1: Table S1; Additional file 2: Figure S1) in the primary tumors of advanced-stage CRC. (B) Tumor LINE-1 methylation levels in CRC patient groups classified according to their best overall response.
Kaneko, Mami, Kotake, Masanori, Bando, Hiroyuki, Yamada, Tetsuji, Takemura, Hirofumi, Toshinari Minamoto   +5 more
openaire   +1 more source

Geographic Structure Without Co‐Divergence: Genomic Insights Into a Highly Specific Symbiosis Between Siphamia Cardinalfish and Their Bioluminescent Symbiont

Ecology and Evolution, Volume 16, Issue 3, March 2026.
In this study, three cardinalfish species in the genus Siphamia, S. tubifer, S. mossambica, and S. fuscolineata, from locations throughout the hosts' broad Indo‐Pacific distribution were analyzed for patterns of genetic divergence along with their luminous bacterial symbionts.
Emily E. Neff, Alison L. Gould
wiley   +1 more source

Additional file 2: Figure S1. of Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

, 2016
The CpG sites in LINE-1 and design of primers used for methylation analysis. (PPTX 78 kb)
Kaneko, Mami, Kotake, Masanori, Bando, Hiroyuki, Yamada, Tetsuji, Takemura, Hirofumi, Toshinari Minamoto   +5 more
openaire   +1 more source

Unveiling Diet Preferences and Their Nutritional Drivers Through Metabarcoding: The Case of Alpine Marmot (Marmota marmota L.) in High Altitude Grazed Pastures

Ecology and Evolution, Volume 16, Issue 3, March 2026.
The alpine marmot (Marmota marmota), a crucial component of alpine ecosystems, serves both as a key player in the food chain and as an ‘ecosystem engineer.’ Employing DNA metabarcoding of fecal samples, this study investigated the diet composition and foraging strategies of four alpine marmot colonies across diverse alpine pasture ecosystems throughout
Giorgio Marchesini, Elena Basso, Cristina Pornaro, Piergiovanni Partel, Gilberto Volcan, Enrico Dorigatti, Rudi Cassini, Erica Marchiori, Salvatore Raniolo, Massimo Pindo, Andrea Squartini   +10 more
wiley   +1 more source

Additional file 5: Table S3. of Prognostic and predictive significance of long interspersed nucleotide element-1 methylation in advanced-stage colorectal cancer

, 2016
Multivariate analysis for the prognostic significance of clinicopathologic factors and tumor LINE-1 methylation in metastatic CRC. (DOCX 27 kb)
Kaneko, Mami, Kotake, Masanori, Bando, Hiroyuki, Yamada, Tetsuji, Takemura, Hirofumi, Toshinari Minamoto   +5 more
openaire   +1 more source

Aging‐Derived Alterations in Genomic, Immune, and Metabolic Networks: Implications for Cancer Development and Therapy

MedComm – Oncology, Volume 5, Issue 1, March 2026.
Ageing acts as a double‐edged sword in cancer. In the elderly, open chromatin, immunosenescence, and chronic inflammation drive SASP (IL‐6, MMPs), MDSC accumulation and T‐cell suppression, fostering tumor‐promoting microenvironments and limited therapeutic benefit.
Qi Wang, Xue Sun, Xinhao Han, Xingda Zhang, Wenzheng Wang, Hongbin Wang, He Ren, Lina Gu   +7 more
wiley   +1 more source