Results 101 to 110 of about 739,569 (400)

Long non-coding RNA SENCR is a positive regulator of ETV2 [PDF]

, 2017
Department of Biological SciencesAlthough long non-coding RNAs (lncRNAs) have emerged as novel regulator of cell fate and gene expression, the regulation of vascular specific transcription factor by lncRNA in generation of induced endothelial cells ...
Jeong, Yujin
core  

Long Non-Coding RNAs in the Cytoplasm

Genomics, Proteomics & Bioinformatics, 2016
Abstract An enormous amount of long non-coding RNAs (lncRNAs) transcribed from eukaryotic genome are important regulators in different aspects of cellular events. Cytoplasm is the residence and the site of action for many lncRNAs. The cytoplasmic lncRNAs play indispensable roles with multiple molecular mechanisms in animal and human ...
Farooq Rashid, Abdullah Shah, Ge Shan
openaire   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Diagnostic value of serum COMP and ADAMTS7 for intervertebral disc degeneration

European Journal of Medical Research
Objective Intervertebral disc degeneration (IVDD) is a major cause of morbidity and disability. Our study aimed to investigate the potential of cartilage oligomeric matrix protein (COMP) and ADAMTS7 (A disintegrin and metalloproteinases with ...
Jing-Yu Ding, Xu Yan, Ren-Jie Zhang, Hua-Qing Zhang, Liang Kang, Chong-Yu Jia, Rick F. Thorne, Xiao-Ying Liu , Cai-Liang Shen   +8 more
doaj   +1 more source

Long non-coding RNA MSTO2P promotes the proliferation and colony formation in gastric cancer by indirectly regulating miR-335 expression

Tumor Biology, 2017
Long non-coding RNAs are emerging as new players in gene regulation, but whether long non-coding RNAs influence the expression of microRNA is unclear.
Han Li, Hua Zhu, Yanbing Zhou, Haibo Wang, Zhaojian Niu, Yi Shen, Liang Lv   +6 more
doaj   +1 more source

MiRNA-related metastasis in oral cancer: moving and shaking

Cancer Cell International, 2023
Across the world, oral cancer is a prevalent tumor. Over the years, both its mortality and incidence have grown. Oral cancer metastasis is a complex process involving cell invasion, migration, proliferation, and egress from cancer tissue either by ...
Meghdad Eslami, Saba Khazeni, Xaniar Mohammadi Khanaghah, Mohammad Hossein Asadi, Mohamad Amin Ansari, Javad Hayati Garjan, Mohammad Hassan Lotfalizadeh, Mobina Bayat, Mohammad Taghizadieh, Seyed Pouya Taghavi, Michael R Hamblin, Javid Sadri Nahand   +11 more
doaj   +1 more source

Whole transcriptome profiling reveals the RNA content of motor axons [PDF]

, 2015
Most RNAs within polarized cells such as neurons are sorted subcellularly in a coordinated manner. Despite advances in the development of methods for profiling polyadenylated RNAs from small amounts of input RNA, techniques for profiling coding and non ...
Appenzeller, Silke, Baluapuri, Apoorva, Briese, Michael, Moradi, Mehri, Saal, Lena, Sendtner, Michael   +5 more
core   +1 more source

MALAT1: a druggable long non-coding RNA for targeted anti-cancer approaches

Journal of Hematology & Oncology, 2018
The deeper understanding of non-coding RNAs has recently changed the dogma of molecular biology assuming protein-coding genes as unique functional biological effectors, while non-coding genes as junk material of doubtful significance. In the last decade,
N. Amodio, L. Raimondi, G. Juli, Maria Angelica Stamato, D. Caracciolo, P. Tagliaferri, P. Tassone   +6 more
semanticscholar   +1 more source

Viruses hijack a long non-coding RNA [PDF]

Nature, 2017
Manipulation of host-cell metabolism is an essential aspect of viral replication cycles. Viral co-option of a cellular long non-protein-coding RNA has now been found to be a key step in this process. Manipulation of host-cell metabolism is an essential aspect of viral replication cycles. Viral co-option of a cellular long non-protein-coding RNA has now
Nicholas S, Heaton, Bryan R, Cullen
openaire   +2 more sources

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source