Results 121 to 130 of about 588,548 (249)

Zipper plot : visualizing transcriptional activity of genomic regions [PDF]

, 2017
Background: Reconstructing transcript models from RNA-sequencing (RNA-seq) data and establishing these as independent transcriptional units can be a challenging task.
Avila Cobos, Francisco, Anckaert, Jasper, Volders, Pieter-Jan, Everaert, Celine, Rombaut, Dries, Vandesompele, Jo, De Preter, Katleen, Mestdagh, Pieter   +7 more
core   +2 more sources

The Landscape of Long Non-Coding RNA Dysregulation and Clinical Relevance in Muscle Invasive Bladder Urothelial Carcinoma. [PDF]

, 2019
Bladder cancer is one of the most common cancers in the United States, but few advancements in treatment options have occurred in the past few decades.
Chang, Eric Y, Chu, Megan, High, Rachel A, Li, Wei Tse, Ongkeko, Weg M, Shen, Haotian, Wang-Rodriguez, Jessica, Wong, Lindsay M   +7 more
core   +1 more source

Identification and function of long non-coding RNAs

Essays in Biochemistry, 2013
It is now clear that eukaryotic cells produce many thousands of non-coding RNAs. The least well-studied of these are longer than 200 nt and are known as lncRNAs (long non-coding RNAs). These loci are of particular interest as their biological relevance remains uncertain.
Robert S. Young, Chris P. Ponting
openaire   +3 more sources

Novel long non-protein coding RNAs involved in Arabidopsis differentiation and stress responses [PDF]

, 2008
Besma Ben Amor, Sonia Wirth, Francisco Merchán, Philippe Laporte, Yves d’Aubenton-Carafa, Judith Hirsch, Alexis Maizel, Allison Mallory, Antoine Lucas, Jean‐Marc Deragon, Hervé Vaucheret, Claude Thermes, Martín Crespi   +12 more
openalex   +1 more source

HDAC3 inhibition mitigates acute kidney injury by alleviating RIPK1-mediated programmed necrosis

Frontiers in Pharmacology
Acute kidney injury (AKI) refers to clinical syndromes culminating in rapidly reduced renal function associated with inflammation and the demise of renal tubular epithelial cells.
Manman Xie, Manman Xie, Rui Hou, Runrun Shan, Xinyu Cheng, Pengcheng Wu, Xiufeng Luo, Yangyang Wei, Li Gao, Xiaoying Liu, Xiaoying Liu, Qi Chen   +11 more
doaj   +1 more source

Prediction of plant lncRNA by ensemble machine learning classifiers

BMC Genomics, 2018
Background In plants, long non-protein coding RNAs are believed to have essential roles in development and stress responses. However, relative to advances on discerning biological roles for long non-protein coding RNAs in animal systems, this RNA class ...
Caitlin M. A. Simopoulos, Elizabeth A. Weretilnyk, G. Brian Golding   +2 more
doaj   +1 more source

Cascade transcription of mRNA-type long non-coding RNAs (mlonRNAs) and local chromatin remodeling [PDF]

, 2009
Kouji Hirota, Kunihiro Ohta
openalex   +1 more source

Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse [PDF]

, 2010
Björn Reinius, Chengxi Shi, Liu Hengshuo, Kuljeet Singh Sandhu, Katarzyna J. Radomska, Glenn D. Rosen, Lu Lu, Klas Kullander, Robert W. Williams, Elena Jazin   +9 more
openalex   +1 more source

Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis [PDF]

, 2010
Rajnish A. Gupta, Nilay Shah, Ke Wang, Jeewon Kim, Hugo M. Horlings, David J. Wong, Miao-Chih Tsai, Tiffany Hung, Pedram Argani, John L. Rinn, Yulei Wang, Pius Brzoska, Benjamin Kong, Rui Li, Robert B. West, Marc J. van de Vijver, Saraswati Sukumar, Howard Y. Chang   +17 more
openalex   +1 more source

RNA-based liquid biopsies for better clinical management of Barrett’s esophagus and esophageal adenocarcinoma [PDF]

, 2019
In the past decades the incidence of esophageal adenocarcinoma (EAC) has increased dramatically in most Western populations. Due to the lack of symptoms EAC is often detected in a late stage, contributing to a poor 5-year survival rate.
De Preter, Katleen, Depypere, Lieven, Nafteux, Philippe, Pattyn, Piet, Philippron, Annouck, Schoofs, Kathleen, Vandesompele, Jo   +6 more
core