Results 131 to 140 of about 492,946 (224)

Functional Polarization of Liver Macrophages by Glyco Gold Nanoparticles

Advanced Science, EarlyView.
Macrophages play a critical role in several pathophysiological diseases by being involved in the activation of adaptive and innate immune responses. The repolarization of macrophages using gold nanoparticles functionalized with glycans for a more selective targeting toward a restorative phenotype leads to an amelioration of the events.
Jennifer Fernandez Alarcon, Patricia Perez Schmidt, Nicolo Panini, Francesca Caruso, Martina B. Violatto, Naths Grazia Sukubo, Alberto Martinez‐Serra, Charlotte Blanche Ekalle‐Soppo, Annalisa Morelli, Giulia Yuri Moscatiello, Chiara Grasselli, Alessandro Corbelli, Fabio Fiordaliso, Joe Kelk, Laura Petrosilli, Giuseppe d'Orazio, Ruth Mateu Ferrando, Ariadna Verdaguer Ferrer, Cristina Fornaguera, Luigi Lay, Stefano Fumagalli, Sandro Recchia, Marco P. Monopoli, Laura Polito, Paolo Bigini, Giovanni Sitia   +25 more
wiley   +1 more source

Uncovering RNA Editing Sites in Long Non-Coding RNAs [PDF]

, 2014
Ernesto Picardi, Anna Maria Dâ€TMErchia, Angela Gallo, Antonio Montalvo, Graziano Pesole   +4 more
openalex   +1 more source

Development of a T cell engaging bispecific antibody targeting long non-coding RNA PVT1. [PDF]

Cancer Immunol Immunother
Kato H, Tsukahara T, Murata K, Nishikata H, Mizue Y, Sasaya T, Kubo T, Kanaseki T, Hirohashi Y, Oyagi A, Maeda T, Miyazaki A, Torigoe T.   +12 more
europepmc   +1 more source

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

Advanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong, Siming Chen, Huimin Xu, Sheng Tu, Hong Weng, Yejinpeng Wang, Mingxing Li, Jingtian Yu, Kaiyu Qian, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Gang Wang   +13 more
wiley   +1 more source

Long non-coding RNAs learn the importance of being in vivo [PDF]

, 2014
Jhumku D. Kohtz
openalex   +1 more source

Chromatin Structure Around Long Non-Coding RNA (lncRNA) Genes in <i>Schistosoma mansoni</i> Gonads. [PDF]

Noncoding RNA
Augusto RC, Quack T, Grevelding CG, Grunau C.   +3 more
europepmc   +1 more source

A 3D Genome Atlas of Genetic Variants and Their Pathological Effects in Cancer

Advanced Science, EarlyView.
The hierarchical organization of the eukaryotic genome is vital for nuclear function, and disruptions from genetic mutations can alter this 3D architecture. Cataloging thousands of interchromosomal translocations, structural variants, and single nucleotide polymorphisms, their impact on 3D genome organization is revealed. The scoring algorithm, 3DFunc,
Li Tang, Matthew C. Hill, Mingxing He, Junhao Chen, Zirui Wang, Patrick T. Ellinor, Min Li   +6 more
wiley   +1 more source

Correlation of long non-coding RNA expression with metastasis, drug resistance and clinical outcome in cancer [PDF]

, 2014
Ehsan Malek, Sajjeev Jagannathan, James J. Driscoll   +2 more
openalex   +1 more source

Genome‐Wide Silencer Screening Reveals Key Silencer Modulating Reprogramming Efficiency in Mouse Induced Pluripotent Stem Cells

Advanced Science, EarlyView.
This study utilized Ss‐STARR‐seq to construct a genome‐wide silencer map of mouse cells and elucidated the fundamental characteristics of these silencers. These silencers exist in a cell‐specific manner and exhibit unique epigenetic modifications. Through functional experiments, we also discovered that these silencers can regulate gene expression and ...
Xiusheng Zhu, Lei Huang, Guoli Li, Biao Deng, Xiaoxiao Wang, Hu Yang, Yuanyuan Zhang, Qiuhan Wen, Chao Wang, Jingshu Zhang, Yunxiang Zhao, Kui Li, Yuwen Liu   +12 more
wiley   +1 more source

What Is the Significance of Long Non-coding RNA HOX Transcript Antisense Intergenic RNA in Gastric Cancer? [PDF]

, 2014
Sang Kil Lee
openalex   +1 more source