The role of circular RNAs in regulating cytokine signaling in cancer
FEBS Open Bio, EarlyView.Cytokines present in the tumor microenvironment fuel cancer development. Aberrant expression of circRNAs contributes to cancer progression. Cytokines are involved in regulating circRNA biogenesis. Furthermore, aberrantly expressed circRNAs regulate the expression of ligands, receptors, and downstream effectors involved in cytokine signaling to promote ...
Vandana Joshi +4 more
wiley +1 more source
Non-coding RNA-mediated regulation of seed endosperm development
Frontiers in Plant ScienceThe endosperm, a triploid nutritive tissue in seeds, plays pivotal roles in embryo development, grain yield and quality. Recent advances highlight non-coding RNAs (ncRNAs) as central regulators of endosperm development, which integrate epigenetic ...
Xinqi Wei +6 more
doaj +1 more source
Female-biased expression of long non-coding RNAs in domains that escape X-inactivation in mouse [PDF]
, 2010 Björn Reinius +9 more
openalex +1 more source
Current trends in single‐cell RNA sequencing applications in diabetes mellitus
FEBS Open Bio, EarlyView.Single‐cell RNA sequencing is a powerful approach to decipher the cellular and molecular landscape at a single‐cell resolution. The rapid development of this technology has led to a wide range of applications, including the detection of cellular and molecular mechanisms and the identification and introduction of novel potential diagnostic and ...
Seyed Sajjad Zadian +6 more
wiley +1 more source
Long non‐coding RNA MALAT1 regulates retinal neurodegeneration through CREB signaling
EMBO Molecular Medicine, 2022 Jin Yao +15 more
doaj +1 more source
HDAC3 inhibition mitigates acute kidney injury by alleviating RIPK1-mediated programmed necrosis
Frontiers in PharmacologyAcute kidney injury (AKI) refers to clinical syndromes culminating in rapidly reduced renal function associated with inflammation and the demise of renal tubular epithelial cells.
Manman Xie +11 more
doaj +1 more source
Large-scale prediction of long non-coding RNA functions in a coding–non-coding gene co-expression network [PDF]
, 2011 Qi Liao +12 more
openalex +1 more source
Liver‐specific lncRNAs associated with liver cancers
FEBS Open Bio, EarlyView.Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina +3 more
wiley +1 more source
Role of non-coding RNA in exosomes for the diagnosis and treatment of osteosarcoma
Frontiers in OncologyOsteosarcoma (OS) is a malignancy characterized by the proliferation of osteoblasts that predominantly affects pediatric and adolescent populations. At present, early detection of OS is significantly lacking, coupled with treatment challenges such as ...
Xin Liu +6 more
doaj +1 more source
EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs. [PDF]
, 2018 BackgroundPolycomb Repressive Complex 2 (PRC2) catalyzes histone methylation at H3 Lys27, and plays crucial roles during development and diseases in numerous systems.
He, Yuan +9 more
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