Results 301 to 309 of about 720,765 (309)
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Long non-coding RNAs and pyroptosis
Clinica Chimica Acta, 2020Long noncoding RNAs (lncRNAs) are defined as transcripts longer than 200 nucleotides that have no or only a low coding potential. They are involved in the progression of multiple diseases by the regulation of mechanisms related to epigenetic modifications and transcriptional and posttranscriptional processing.
Dong He +4 more
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Infectious long non-coding RNAs
Biochimie, 2015Long non protein coding RNAs (lncRNAs) constitute a large category of the RNA world, able to regulate different biological processes. In this review we are focusing on infectious lncRNAs, their classification, pathogenesis and impact on the infected organisms.
Kriton Kalantidis +3 more
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Long non-coding RNAs in metastasis
Cancer and Metastasis Reviews, 2017Long non-coding RNA (lncRNA) genes have recently been discovered as key regulators of developmental, physiological, and pathological processes in humans. Recent studies indicate that lncRNAs regulate every step of gene expression, and their aberrant expression can be found in the majority of cancer types. Particularly, lncRNAs were found to function in
Reuven Agami, Qihong Huang, Jinchun Yan
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Long Non-coding RNAs in Rheumatology
2022The last decade has seen an enormous increase in long non-coding RNA (lncRNA) research within rheumatology. LncRNAs are arbitrarily classed as non-protein encoding RNA transcripts that exceed 200 nucleotides in length. These transcripts have tissue and cell specific patterns of expression and are implicated in a variety of biological processes ...
Susanne N, Wijesinghe +2 more
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Long non-coding RNAs in retinoblastoma
Pathology - Research and Practice, 2019Retinoblastoma represents 3% of all childhood cancers and is the most common intraocular malignant tumor with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have reported new insights into the mechanism of retinoblastoma development, the involvement of regulatory non-coding RNAs remains unclear.
Wenbin Wei, Ming Yang
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Long non-coding RNAs: Guardians of development
Differentiation, 2010Two decades ago, the existence of long non-coding RNAs (lncRNAs) was discovered. In the following genomics era more transcribed non-coding genomic regions were identified. These were initially regarded as transcriptional noise and did not receive a lot of attention.
Leeuwen, S. van, Mikkers, H.
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Long non-coding RNAs and chromatin regulation
Current Opinion in Plant Biology, 2011Microarray analysis and new sequencing technologies have revealed that the majority of the genome is transcribed in many eukaryotes. Much of the RNA appears to be non-coding and an ongoing debate is how much of a functional role it has. Different mechanisms by which ncRNA can be regulatory have been described: direct ncRNA effects on transcription ...
Filomena De Lucia, Caroline Dean
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