Results 321 to 330 of about 718,965 (394)

Extracellular vesicle‐mediated transfer of long non‐coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

, 2014
Kenji Takahashi, Irene K. Yan, Takayuki Kogure, Hiroaki Haga, Tushar Patel   +4 more
openalex   +1 more source

Endothelial BMP6 Drives Hemodynamic‐Dependent VSMCs Calcification in Carotid Atherosclerosis

Advanced Science, EarlyView.
The study demonstrates that endothelial cell (EC)‐derived BMP6 promotes the osteogenic differentiation of vascular smooth muscle cells (VSMCs) through cell‐cell interactions. Additionally, the researchers preliminarily explore the driving effect of hemodynamic factors on BMP6‐induced calcification and reveal the regulatory role of KLF4 on BMP6.
Shen Li, Shuang Cao, Peipei Li, Feng Zhang, Gangfeng Ren, Xin Wang, Jiawei Zhao, Chen Liu, Yuan Gao, Jie Xu, Yongjun Wang, Zongping Xia, Yuming Xu   +12 more
wiley   +1 more source

Identification and validation of a ferroptosis-related long non-coding RNA signature as a prognostic biomarker for hepatocellular carcinoma. [PDF]

J Gastrointest Oncol
Yu T, Chen X, Li S, Ladekarl M, Li J.
europepmc   +1 more source

Long non-coding RNAs in the regulation of the immune response

, 2014
James A. Heward, Mark A. Lindsay
openalex   +1 more source

Pectin Metabolism Influences Phloem Architecture and Flowering Time in Arabidopsis Thaliana

Advanced Science, EarlyView.
Cell wall remodeling mediated by changes in pectic homogalacturonan, including its methyl‐esterification status and degradation, shapes wall architecture. This study finds that pectin metabolism dynamically modulates wall properties and triggers auxin responses, which influence phloem morphogenesis and function, mediating the long‐distance transport of
Qing Zhang, Juan Du, Shuang Hao, Zhengmei Leng, Weiguo Liu, Chengjian Zhao, Yue Yu, Longquan Chen, Charles T. Anderson, Chaowen Xiao   +9 more
wiley   +1 more source

Long non-coding RNA SNHG7 as a key driver of colorectal cancer proliferation and metastasis by inhibiting cuproptosis. [PDF]

Eur J Med Res
Guo X, He X, Chen W, Zhou J, Lyu Z, Li Z, Li Y.   +6 more
europepmc   +1 more source

FOXQ1 Regulates Brain Endothelial Mitochondrial Function by Orchestrating Calcium Signaling and Cristae Morphology

Advanced Science, EarlyView.
FOXQ1 emerges as a master transcriptional regulator of brain endothelial metabolism, orchestrating mitochondrial function through dual control of calcium signaling and cristae organization. This study reveals that brain endothelial cells rely on oxidative phosphorylation rather than glycolysis alone, challenging the current metabolic paradigm and ...
Wenzheng Zou, Yuqing Lv, Lin Li, Shukui Zhang, Jiaqi Liang, Chengchao Wu, Enyu Huang, Jianwei Jiao, Jingjing Zhang   +8 more
wiley   +1 more source

Targeting long non-coding RNA <i>MALAT1</i> preserves endothelial cell integrity and protects against kidney fibrosis. [PDF]

Mol Ther Nucleic Acids
Zhao Q, van der Pluijm LAK, Gourvest M, Lafzi A, Peled D, Rubin WG, de Klerk JA, Slieker RC, 't Hart LM, Stam W, van Oeveren-Rietdijk AM, Duijs JMGJ, Koudijs A, Rotmans JI, Kazan H, van Zonneveld AJ, van Solingen C, Bijkerk R.   +17 more
europepmc   +1 more source

USP45 Represses Melanoma Development by Deubiquitinating and Stabilizing Tumor Suppressor MRGPRF

Advanced Science, EarlyView.
USP45 acts as a melanoma suppressor by stabilizing MRGPRF, which weakens the PI3K/AKT pathway, suppresses tumor growth, and reduces melanoma cell migration and invasion. Abstract Melanoma, a highly malignant skin cancer, has seen a rising incidence and death toll. MRGPRF is a novel melanoma suppressor that inhibits the PI3K/AKT pathway.
Wancong Zhang, Liyun Chen, Jing Zhao, Aiwei Ma, Wenqi Shi, Yiwen Zhang, Zixuan Tang, Jiarui Guo, Zaihua Xu, Jianda Zhou, Shijie Tang   +10 more
wiley   +1 more source

Transcriptional stochasticity reveals multiple mechanisms of long non-coding RNA regulation at the Xist-Tsix locus. [PDF]

Nat Commun
Kesler BK, Adams J, Neuert G.
europepmc   +1 more source