Results 341 to 350 of about 703,919 (374)

Metastasis-Specific CpG Island DNA Hypermethylation of the Long Non-Coding RNA Gene <i>00404</i> in Renal Cell Carcinoma. [PDF]

Cancers (Basel)
Faraj Tabrizi P, Schimansky I, Peters I, Hennenlotter J, Tezval H, Kuczyk MA, Serth J.   +6 more
europepmc   +1 more source

Genomic and Cis‐Regulatory Basis of a Plastic C3‐C4 Photosynthesis in Eleocharis Baldwinii

Advanced Science, EarlyView.
The sedge Eleocharis baldwinii remarkably switches between C3‐like and C4‐like photosynthesis in response to environmental conditions. Combining gap‐free genome assembly with single‐cell multi‐omics, this study uncovers how subgenome dominance and cell‐specific cis‐regulation enable C4 photosynthesis.
Lu Chen, Yanfeng Jia, Zaihui Zhou, Qiying Jiang, Jianlin Liu, Jianhui Gu, Chuan Chen, Shujing Cheng, Jinfang Chu, Xin Liu, Yongjun Lin, Xiang Li   +11 more
wiley   +1 more source

Correction 'LncPepAtlas: a comprehensive resource for exploring the translational landscape of long non-coding RNA'. [PDF]

Nucleic Acids Res
europepmc   +1 more source

The Relevance of the Accurate Annotation of Micro and Long Non-Coding RNA Interactions for the Development of Therapies. [PDF]

Genes (Basel)
Panni S.
europepmc   +1 more source

The DEC2‐SCN2A Axis is Essential for the Anticonvulsant Effects of Cannabidiol by Modulating Neuronal Plasticity

Advanced Science, EarlyView.
This study identifies DEC2 as a critical transcriptional repressor of Scn2a that directly binds E‐box motifs in its promoter to regulate neuronal plasticity and epileptogenesis. Functional manipulation of DEC2 alters seizure susceptibility in vivo. Cannabidiol enhances this repression, unveiling a novel DEC2‐SCN2A axis underlying its anticonvulsant ...
Huifang Song, Yifan Wang, Lili Wang, Chang Guo, Shiqi Liu, Yi Rong, Jiawen Tian, Chao Peng, Yuying Shao, Zhixiong Ma, Na Li, Jingliang Zhang, Zijun Peng, Xu Yan, Hangwei Fa, Xinyue Ma, Jie Dong, Jinping Ji, Chen Yang, Haocheng Chen, Jing Liang, Qi Sun, Yang Yang, Weining Ma, Zhuo Huang   +24 more
wiley   +1 more source

Comprehensive Characterization of Bihormonal Cells and Endocrine Cell Lineages in Mammalian Pancreatic Islets

Advanced Science, EarlyView.
This study integrates dual‐reporter genetics, imaging flow cytometry, and single‐cell sequencing to characterize rare bihormonal cells in mouse and human pancreatic islets. Gcg⁺Ins⁺ cells resemble α‐cells rather than transitional states. Cross‐species gene network analysis refines islet cell taxonomy and reveals human‐specific δ‐cell subtypes ...
Xin‐Xin Yu, Peng Peng, Yi‐Ning Wang, Mao‐Yang He, Shuang He, Chen‐Tao Jin, Liu Yang, Xi Wang, Jia‐Xi Zheng, Jie Gao, Cheng‐Ran Xu   +10 more
wiley   +1 more source

Loss of conserved long non-coding RNA MIR503HG leads to altered NOTCH pathway signalling and left ventricular non-compaction cardiomyopathy. [PDF]

Cardiovasc Res
Monteiro JP, Saha D, Spiroski AM, Mahesh S, Kaltzis P, Nadavallil A, Janbandhu V, Murray NJ, Severi F, Severi F, De Pace AL, Sánchez-Esteban S, Rodor J, Beqqali A, Bennett M, Stewart K, Thomson A, Hadoke PWF, Markose D, Wilson-Kanamori JR, Henderson NC, O'Carroll D, Quertermous T, Harvey RP, Del Monte-Nieto G, Baker AH.   +25 more
europepmc   +1 more source

[Retracted] Silencing of long non-coding RNA SNHG15 suppresses proliferation, migration and invasion of pancreatic cancer cells by regulating the microRNA-345-5p/RAB27B axis. [PDF]

Exp Ther Med
Jiang P, Yin Y, Wu Y, Sun Z.
europepmc   +1 more source