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Long non-coding RNAs in retinoblastoma

Pathology - Research and Practice, 2019
Retinoblastoma represents 3% of all childhood cancers and is the most common intraocular malignant tumor with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have reported new insights into the mechanism of retinoblastoma development, the involvement of regulatory non-coding RNAs remains unclear.
Wenbin Wei, Ming Yang
openaire   +3 more sources

Long non-coding RNAs in schizophrenia

Clinica Chimica Acta
Long noncoding RNAs (lncRNAs) have emerged as critical regulators of the pathogenesis of schizophrenia, a complex neuropsychiatric disorder influenced by genetic and environmental factors. These transcripts modulate gene expression through diverse mechanisms, including chromatin remodeling, transcriptional regulation, and posttranscriptional ...
Seyyed Navid, Mousavinejad   +6 more
openaire   +2 more sources

Long non-coding RNAs: Guardians of development

Differentiation, 2010
Two decades ago, the existence of long non-coding RNAs (lncRNAs) was discovered. In the following genomics era more transcribed non-coding genomic regions were identified. These were initially regarded as transcriptional noise and did not receive a lot of attention.
Leeuwen, S. van, Mikkers, H.
openaire   +4 more sources

Long non-coding RNAs and chromatin regulation

Current Opinion in Plant Biology, 2011
Microarray analysis and new sequencing technologies have revealed that the majority of the genome is transcribed in many eukaryotes. Much of the RNA appears to be non-coding and an ongoing debate is how much of a functional role it has. Different mechanisms by which ncRNA can be regulatory have been described: direct ncRNA effects on transcription ...
Filomena De Lucia, Caroline Dean
openaire   +3 more sources

Unique features of long non-coding RNA biogenesis and function

Nature reviews genetics, 2015
Jeffrey J. Quinn, Howard Y. Chang
semanticscholar   +1 more source

Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress

Nature Metabolism, 2021
L. Sang   +23 more
semanticscholar   +1 more source

Cancer Statistics, 2021

Ca-A Cancer Journal for Clinicians, 2021
Rebecca L Siegel, Kimberly D Miller
exaly  

Long non-coding RNA mediated drug resistance in breast cancer.

Drug resistance updates, 2022
Deepshikha Singh, Y. Assaraf, R. Gacche
semanticscholar   +1 more source

Melanoma addiction to the long non-coding RNA SAMMSON

Nature, 2016
E. Leucci   +23 more
semanticscholar   +1 more source

Cancer statistics, 2020

Ca-A Cancer Journal for Clinicians, 2020
Rebecca L Siegel, Kimberly D Miller
exaly  

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