Results 361 to 370 of about 703,919 (374)

Long non-coding RNAs in metastasis

Cancer and Metastasis Reviews, 2017
Long non-coding RNA (lncRNA) genes have recently been discovered as key regulators of developmental, physiological, and pathological processes in humans. Recent studies indicate that lncRNAs regulate every step of gene expression, and their aberrant expression can be found in the majority of cancer types. Particularly, lncRNAs were found to function in
Reuven Agami, Qihong Huang, Jinchun Yan
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Long Non-coding RNAs in Rheumatology

2022
The last decade has seen an enormous increase in long non-coding RNA (lncRNA) research within rheumatology. LncRNAs are arbitrarily classed as non-protein encoding RNA transcripts that exceed 200 nucleotides in length. These transcripts have tissue and cell specific patterns of expression and are implicated in a variety of biological processes ...
Susanne N, Wijesinghe, Mark A, Lindsay, Simon W, Jones   +2 more
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Long non-coding RNAs in retinoblastoma

Pathology - Research and Practice, 2019
Retinoblastoma represents 3% of all childhood cancers and is the most common intraocular malignant tumor with a highly aggressive and metastatic phenotype. While recent genetic and epigenetic studies have reported new insights into the mechanism of retinoblastoma development, the involvement of regulatory non-coding RNAs remains unclear.
Wenbin Wei, Ming Yang
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Long non-coding RNAs: Guardians of development

Differentiation, 2010
Two decades ago, the existence of long non-coding RNAs (lncRNAs) was discovered. In the following genomics era more transcribed non-coding genomic regions were identified. These were initially regarded as transcriptional noise and did not receive a lot of attention.
Leeuwen, S. van, Mikkers, H.
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Long non-coding RNAs in schizophrenia

Clinica Chimica Acta
Long noncoding RNAs (lncRNAs) have emerged as critical regulators of the pathogenesis of schizophrenia, a complex neuropsychiatric disorder influenced by genetic and environmental factors. These transcripts modulate gene expression through diverse mechanisms, including chromatin remodeling, transcriptional regulation, and posttranscriptional ...
Seyyed Navid, Mousavinejad, Seyed Ali, Hosseini, Mozhdeh, Mohammadpour, Felora, Ferdosi, Ehsan, Dadgostar, Siavash, Abdolghaderi, Seyyed Hossein, Khatami   +6 more
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Long non-coding RNAs and chromatin regulation

Current Opinion in Plant Biology, 2011
Microarray analysis and new sequencing technologies have revealed that the majority of the genome is transcribed in many eukaryotes. Much of the RNA appears to be non-coding and an ongoing debate is how much of a functional role it has. Different mechanisms by which ncRNA can be regulatory have been described: direct ncRNA effects on transcription ...
Filomena De Lucia, Caroline Dean
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Unique features of long non-coding RNA biogenesis and function

Nature reviews genetics, 2015
Jeffrey J. Quinn, Howard Y. Chang
semanticscholar   +1 more source

Long non-coding RNA mediated drug resistance in breast cancer.

Drug resistance updates, 2022
Deepshikha Singh, Y. Assaraf, R. Gacche
semanticscholar   +1 more source

Melanoma addiction to the long non-coding RNA SAMMSON

Nature, 2016
E. Leucci, Roberto Vendramin, M. Spinazzi, P. Laurette, M. Fiers, J. Wouters, E. Radaelli, S. Eyckerman, C. Leonelli, K. Vanderheyden, A. Rogiers, Els Hermans, P. Baatsen, S. Aerts, F. Amant, S. Aelst, J. Oord, B. Strooper, I. Davidson, D. Lafontaine, K. Gevaert, J. Vandesompele, P. Mestdagh, J. Marine   +23 more
semanticscholar   +1 more source

Diagnostic, prognostic, and therapeutic significance of long non-coding RNA MALAT1 in cancer.

Biochimica et biophysica acta. Reviews on cancer, 2021
B. Goyal, S. Yadav, Nikee Awasthee, Sweety Gupta, A. Kunnumakkara, S. C. Gupta   +5 more
semanticscholar   +1 more source