Results 121 to 130 of about 34,480 (242)

Structural and Echocardiographic Abnormalities in Congenital Long QT Syndrome: A Review of the Literature. [PDF]

Medicina (Kaunas)
Markevičiūtė A, Lapinskaitė P, Kovalevska M, Vaitiekienė A, Rinkūnienė D.   +4 more
europepmc   +1 more source

Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of 5‐HT3 Receptor Antagonists: 2026 Update

Clinical Pharmacology &Therapeutics, Volume 120, Issue 2, Page 387-393, August 2026.
5‐hydroxytryptamine type 3 (5‐HT3) receptor antagonists are used to treat nausea and vomiting and in the prevention of chemotherapy‐induced, radiation‐induced, and postoperative nausea and vomiting. Most of the 5‐HT3 receptor antagonists (i.e., ondansetron, tropisetron, dolasetron, palonosetron, and ramosetron) are metabolized by CYP2D6, but the extent
Claire Moore, Melissa S. Bourque, Andreas Halman, José A. G. Agúndez, Cynthia A. Prows, Keiko Hikino, Matthias Schwab, Carolyn J. Oxencis, Dharmisha Chauhan, Meta H.M. Diekstra, Susie E. Long, Gillian C. Bell, Andrea Gaedigk, Michelle Whirl‐Carrillo, Teri E. Klein, Kelly E. Caudle, Rachel Conyers   +16 more
wiley   +1 more source

Long QT Syndrome Type 5 With Coexisting KCNE1 and RYR2 Variants: A Diagnostic Ambiguity. [PDF]

Clin Case Rep
Nikoo MH, Fatemian H, Hassani AH, Rabiee Rad M, Mostafavi S.   +4 more
europepmc   +1 more source

ADAMTS4 mediates LPS‐induced cardiac injury and myocardial fibrosis through proteolytic cleavage of TSP1

Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.
• ADAMTS4 is induced primarily in cardiac fibroblasts during sepsis. • ADAMTS4 cleaves TSP1 at the 236–246 aa functional region. • TSP1 cleavage activates TGF‐β/Smad and NF‐κB signalling in fibroblasts. • Targeting ADAMTS4 reduces fibroblast activation and cardiac fibrosis.
Zhe‐Wei Zhang, Shi‐Yan Wan, Wen Li, Xiao Lu, Rong Chen, Xin Xing, Wei Lai, Shu‐Yang Sheng, M. M. Mosebetsi, Qing‐Tao Meng, Zi‐Long Lu, Di Fan, Wan‐Li Jiang   +12 more
wiley   +1 more source

Long QT syndrome and hypoglycemia in a postbariatric surgery patient with a likely pathogenic variant in <i>KCNE1</i>. [PDF]

JCEM Case Rep
Arevalo-Rios ECE, Mateo-Collado R, Kim H, Isganaitis E, Kulkarni RN, Patti ME.   +5 more
europepmc   +1 more source

Practices of Antifungal Prophylaxis Among Italian Pediatric Oncology–Hematology Centers

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Background IFD is a significant cause of illness and death among pediatric patients undergoing chemotherapy or HSCT. Application of AFP in children varies widely and is frequently off‐label. This survey aims to describe real‐world AFP practices across centers within AIEOP and provide an estimate of IFD incidence.
Martina Colli, Antonio Grasso, Manuela Spadea, Francesca Compagno, Lorenzo Chiusaroli, Paola Muggeo, Alessia Pancaldi, Rosamaria Mura, Daniela Onofrillo, Raffaella De Santis, Beatrice Mongelli, Angelica Barone, Simona Rinieri, Paola Coccia, Erica Ricci, Maura Faraci, Maria Rosaria D'Amico, Federica Galaverna, Pietro Gasperini, Letizia Brescia, Antonella Colombini, Riccardo Masetti, Francesco Baccelli, Simone Cesaro   +23 more
wiley   +1 more source

Cardiac arrest due to acquired long QT syndrome during gynecologic laparoscopy: a case report. [PDF]

Front Med (Lausanne)
Wang W, Wang R, Li G, Zhang Y.
europepmc   +1 more source

Catheter Ablation Outcomes in Electrical Storm Versus Non–Electrical Storm Ventricular Tachycardia: A Systematic Review and Meta‐Analysis

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
Catheter ablation for ventricular tachycardia showed comparable acute procedural success and complication rates in patients with and without electrical storm. However, electrical storm was associated with higher in‐hospital mortality, long‐term mortality, and ventricular tachycardia recurrence, supporting its role as a marker of adverse prognosis ...
Ahmad Jalil, Fatima Rajab, Xuan Li, Abdulgafar Ibrahim, Arundhati Sawant, Michael Bashir, Varshitha Bandi, Karan Bhatt, Smit Mehta, Bilal Abaid, Arthur Alencar, Mahmoud Gomaa, Muhammad Afzal   +12 more
wiley   +1 more source

Not All "Idiopathic" PVCs Are Benign: Concealed Long QT Syndrome Unmasked by RVOT PVC Ablation. [PDF]

J Arrhythm
Tran KD, Nguyen NDS, Lo LW, Luong SC.
europepmc   +1 more source

R1 Prognostic Significance of T‐Wave Amplitude Variability for Adverse Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis

Journal of Arrhythmia, Volume 42, Issue 4, August 2026.
In this systematic review and meta‐analysis of seven studies involving 1366 patients, elevated T‐wave amplitude variability (TAV) was associated with a 2.5‐fold higher risk of adverse cardiovascular outcomes. These findings support TAV as a marker of ventricular repolarization instability for long‐term risk stratification.
Yoshihiro Sobue, Kazuya Takeda, Mari Amino, Koichiro Yoshioka, Tomohide Ichikawa, Eiichi Watanabe   +5 more
wiley   +1 more source