Results 121 to 130 of about 38,746 (286)

Outcomes of a Routine Screening Protocol to Prevent Metamycoplasma and Ureaplasma Infection in Lung Transplant Recipients

Transplant Infectious Disease, EarlyView.
This study analyzed outcomes of an early Mollicute (Mycoplasma hominis and Ureaplasma spp.) screening protocol using BAL PCR with preemptive treatment and ammonia monitoring in lung transplant recipients. This appears to be a practical and reasonably effective approach for preventing early Mollicute infection and hyperammonemia syndrome.
Lalithaa Thirunavukarasu Murugan, Anika Sasidharan Nair, Marie M. Budev, Maureen Converse, Nabin K. Shrestha, Christine E. Koval   +5 more
wiley   +1 more source

Electrophysiologic testing in patients with the long QT syndrome.

, 1985
Electrophysiologic studies were performed in 15 patients with syncope and/or cardiac arrest who had the long QT syndrome and 11 control subjects who had normal QT intervals. The syndrome was familial in five patients and idiopathic in 10.
F Morady, M M Scheinman, A K Bhandari, E N Shen, J Mason, W A Shapiro   +5 more
core   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

The genetic architecture of long QT syndrome: A critical reappraisal

, 2018
Collectively, the completion of the Human Genome Project and subsequent development of high-throughput next-generation sequencing methodologies have revolutionized genomic research.
Giudicessi, John R., Michael J. Ackerman, Arthur A.M. Wilde, Wilde, Arthur A. M., John R. Giudicessi, Ackerman, Michael J.   +5 more
core   +1 more source

In silico modelling of multi‐electrode arrays for enhancing cardiac drug testing on hiPSC‐CM heterogeneous tissues

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic overview of the experimental and computational framework for investigating hiPSC‐CM electrophysiology with MEA systems. The MEA‐based model integrates experimental data with phenotype‐specific ionic models and tissue‐level heterogeneity.
Sofia Botti, Rolf Krause, Luca F. Pavarino   +2 more
wiley   +1 more source

The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated the age‐ and sex‐related differences in the apicobasal repolarization gradient (ABRG) and evaluated their possible role inventricular arrhythmia vulnerability. Electrocardiographic imaging (ECGI) was performed in healthy subjects during sinus rhythm, and the average recovery time (RT) and activation–recovery ...
Vladimír Sobota, Job Stoks, Kiran Haresh Kumar Patel, Roshni Shetty, Haibo Ni, Eleonora Grandi, Fu Siong Ng, Paul G. A. Volders, Matthijs J. M. Cluitmans, Jason D. Bayer   +9 more
wiley   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

The long QT syndrome

, 2014
The long QT syndrome (LQTS) is an arrhythmogenic syndrome due to cardiac ion channel disorders characterized by prolonged QT interval on ECG (QTc >440 ms for male, >460 ms for female) and the most common presentations are syncope, seizures, cardiac
Marzuillo P., Bonazza P., Berton E., Germani C., Barbi E., D'Alfonso R., Ferrara G.   +6 more
core  

Repolarization adaptation to rapid change in heart rate in human models – a review

The Journal of Physiology, EarlyView.
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt, Karl‐Jonas Axelsson, Pia Dahlberg, Farzad Vahedi, Gunilla Lundahl, Lennart Gransberg   +5 more
wiley   +1 more source

Long QT Syndrome in Athletes: Challenges in the Diagnosis and Management: Long QT Syndrome in Athletes

, 2021
The long QT syndrome (LQTS) is an inherited channelopathy characterized by a prolonged QT interval without structural heart disease posing a risk of sudden cardiac death.
Pastromas, Sokratis
core