Results 121 to 130 of about 7,350,665 (262)
Restricting excessive cardiac action potential and QT prolongation: a vital role for IKs in human ventricular muscle [PDF]
, 2005 Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Lengyel, Csaba Attila +10 more
core +1 more source
The Journal of Physiology, EarlyView.Abstact figure legend A panoramic 3D optical mapping system was developed, enabling imaging of action potential waves across the entire strongly deforming ventricular surface of beating isolated hearts. The system comprises 12 high‐speed cameras and a soccerball‐shaped imaging chamber with 48 light‐emitting diodes (LEDs).
Shrey Chowdhary +5 more
wiley +1 more source
Electrophysiologic testing in patients with the long QT syndrome.
, 1985 Electrophysiologic studies were performed in 15 patients with syncope and/or cardiac arrest who had the long QT syndrome and 11 control subjects who had normal QT intervals. The syndrome was familial in five patients and idiopathic in 10.
F Morady +5 more
core +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A mechanistic framework linking sex‐dependent dynamical instability to proarrhythmic risk. Sex‐specific human ventricular models show that upstream modulators, including biological sex, hormones, drugs and heart disease, promote steeper APD restitution in female than male and enhance dynamical instability.
Daisuke Sato +3 more
wiley +1 more source
Anesthetic Management of a Patient with Congenital Long QT Syndrome [PDF]
, 2004 Long QT syndrome is characterized by syncope and fatal ventricular arrhythmia or fibrillation at an young age. A 25-year-old female patient with congenital Long QU syndrome (Jervell and Lange-Nielsen syndrome) was scheduled for cochlea implantation due ...
구본녀 +3 more
core
hERG1 channels and potential therapeutics for long QT syndrome
The Journal of Physiology, EarlyView.Abstract figure legend Prolonged QT results from hERG1 channel dysfunction. (A) Physiological anterograde trafficking of hERG1 channels to the plasma membrane, leading to a normal electrocardiogram. (B) Prolonged QT results from the presence of fewer hERG1 channels on the plasma membrane due to decreased anterograde trafficking or reduced function due ...
Elizabeth H. Schneider +3 more
wiley +1 more source
Ventricular Repolarization and the Long QT Syndrome [PDF]
, 2005 In 1895 Willem Einthoven first described the electrocardiogram. The electrical activation of the heart and its translation into the body surface ECG was revealed by Durrer in 1970.
Conrath, Chantal Elisabeth +1 more
core +1 more source
Congenital long QT syndrome: The masquerader
Indian Journal of Anaesthesia, 2022 Bincy V Thomas +3 more
doaj +1 more source
Journal of the Peripheral Nervous System, Volume 31, Issue 4, December 2026.ABSTRACT Background and Aims Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is an immune‐mediated neuropathy that may cause persistent disability despite immunoglobulin treatment. Ion channel dysfunction has been demonstrated in CIDP, but no therapies specifically target this mechanism.
Peter Nørregaard Hansen +5 more
wiley +1 more source