Results 111 to 120 of about 34,480 (242)
A clinically aligned two‐stage machine learning framework integrates preoperative and perioperative features to predict hungry bone syndrome after parathyroidectomy. Explainable risk stratification may support individualised calcium management and early intervention for high‐risk patients.
Shih‐Min Yin +10 more
wiley +1 more source
ABSTRACT Objective The albumin‐globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).
Eylem Şerife Kalkan +5 more
wiley +1 more source
ABSTRACT Background Intravenous lidocaine therapy (IVLT) is often used in perioperative multimodal analgesia due to its analgesic, anti‐hyperalgesic, and anti‐inflammatory effects. In adults, IVLT doses of 1–2 mg/kg/h produce plasma concentrations of 1–2 μg/mL, within the presumed therapeutic range of 1–5 μg/mL.
McKenna Postles +3 more
wiley +1 more source
ABSTRACT Purpose The prescribing of 5‐hydroxytryptamine 3 receptor and type 3 serotonin receptor (5‐HT3) antagonists, particularly ondansetron, for nausea and vomiting in pregnancy (NVP) has increased globally. However, evidence on the safety of these medications in pregnancy remains unclear.
Shannon Morgan +6 more
wiley +1 more source
Optimization of novel compounds using computer‐aided drug design for treatment of cardiac arrhythmia
Background and Purpose Loss‐of‐function mutations of the voltage‐gated Kv7.1 (KCNQ/KCNE1) channels lead to cardiac arrhythmia such as long QT syndrome, characterized by a prolonged QT interval . One strategy to correct the prolonged QT interval is to design molecules that activate KCNQ1/KCNE1 channels and restore the QT interval.
Jessica Jowais +4 more
wiley +1 more source
On the History of Hepatic Vein Catheterization
ABSTRACT Hepatic vein catheterization (HVC) in man was first performed 80 years ago in the wake of right‐sided heart catheterization. Several new methods, recognitions and concepts followed, especially the indirect Fick‐method for determination of splanchnic blood flow. Five years passed before pressure measurements were performed and routine HVCs were
Jens Henrik Henriksen +2 more
wiley +1 more source
Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang +7 more
wiley +1 more source
Abstract Background and Purpose Drug–drug interactions (DDIs) are associated with an increased risk of adverse drug reactions (ADRs). Hospitalized children are particularly vulnerable to DDIs and ADRs due to polypharmacy, frequent use of unlicensed or off‐label medications, and dosing regimens often extrapolated from adult data.
Emilie Laval +6 more
wiley +1 more source
ABSTRACT Desmin, a crucial intermediate filament in muscle cells, maintains structural integrity in cardiac muscle and provides stability to striated muscle cells. Mutations in the DES gene lead to desminopathies, causing diverse cardiac and skeletal myopathies.
Saeideh Kavousi +5 more
wiley +1 more source
ABSTRACT This case illustrates the rare clinical emergence of the short‐coupled ventricular fibrillation (SC‐VF) phenotype during the subacute remodeling phase following acute myocardial infarction (AMI). Although SC‐VF is traditionally characterized as an idiopathic syndrome occurring in structurally normal hearts, we report the case of a 49‐year‐old ...
ZiYu Zhao, Ming Ni, Bo Li, Songhua Li
wiley +1 more source

