Results 161 to 170 of about 266,382 (322)

Gap junctional and ephaptic coupling in cardiac electrical propagation: homocellular and heterocellular perspectives

The Journal of Physiology, EarlyView.
Abstract figure legend Intricate cellular electrical coupling networks in the heart. Various cell types couple the central cardiomyocyte through gap junctional contacts, with the exception of neurons. Whether ephaptic coupling (EpC) occurs in homocellular or heterocellular contexts beyond cardiomyocyte–cardiomyocyte interactions remains unclear ...
Xiaobo Wu, Laura Beth Payne, Robert G. Gourdie   +2 more
wiley   +1 more source

A de novo missense mutation of human cardiac Na⁺ channel exhibiting novel molecular mechanisms of long QT syndrome [PDF]

, 1998
Naomasa Makita, Nobumasa Shirai, Masato Nagashima, Rumiko Matsuoka, Yoichi Yamada, Noritsugu Tohse, Akira Kitabatake   +6 more
openalex   +1 more source

Anesthetic Management of a Patient with Congenital Long QT Syndrome [PDF]

, 2004
Long QT syndrome is characterized by syncope and fatal ventricular arrhythmia or fibrillation at an young age. A 25-year-old female patient with congenital Long QU syndrome (Jervell and Lange-Nielsen syndrome) was scheduled for cochlea implantation due ...
강원철, 구본녀, 길혜금, 박윤곤   +3 more
core  

The apicobasal dispersion of ventricular repolarization in humans is associated with age and affects arrhythmia vulnerability

The Journal of Physiology, EarlyView.
Abstract figure legend We investigated the age‐ and sex‐related differences in the apicobasal repolarization gradient (ABRG) and evaluated their possible role inventricular arrhythmia vulnerability. Electrocardiographic imaging (ECGI) was performed in healthy subjects during sinus rhythm, and the average recovery time (RT) and activation–recovery ...
Vladimír Sobota, Job Stoks, Kiran Haresh Kumar Patel, Roshni Shetty, Haibo Ni, Eleonora Grandi, Fu Siong Ng, Paul G. A. Volders, Matthijs J. M. Cluitmans, Jason D. Bayer   +9 more
wiley   +1 more source

Novel missense mutation (G601S) of HERG in a Japanese long QT syndrome family [PDF]

, 1998
Kaoru Akimoto, Michiko Furutani, Shinichiro Imamura, Yoshiyuki Furutani, Hiroshi Kasanuki, Atsuyoshi Takao, Kazuo Momma, Rumiko Matsuoka   +7 more
openalex   +1 more source

14‐3‐3 proteins: Regulators of cardiac excitation–contraction coupling and stress responses

The Journal of Physiology, EarlyView.
Abstract figure legend 14‐3‐3 protein interactions in cardiac regulation. Schematic representation of 14‐3‐3 binding partners in excitation–contraction coupling, transcriptional regulation/development and stress response pathways. Asterisks indicate targets where the exact 14‐3‐3 binding site is unknown.
Heather C. Spooner, Rose E. Dixon
wiley   +1 more source

Positive head-up tilt table test in patients with the long QT syndrome [PDF]

, 1999
Antonio G. Hermosillo, Juan C. Suárez‐Falcón, Manlio F. Márquez, Diana Arteaga, M Cárdenas   +4 more
openalex   +1 more source

SCN5A mutations associated with an inherited cardiac arrhythmia, long QT syndrome

Cell, 1995
Qing Wang, Jiaxiang Shen, I. Splawski, D. Atkinson, Zhizhong Li, Jennifer L. Robinson, A. Moss, J. Towbin, M. Keating   +8 more
semanticscholar   +1 more source

Repolarization adaptation to rapid change in heart rate in human models – a review

The Journal of Physiology, EarlyView.
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt, Karl‐Jonas Axelsson, Pia Dahlberg, Farzad Vahedi, Gunilla Lundahl, Lennart Gransberg   +5 more
wiley   +1 more source

Rescue of loss‐of‐function long QT syndrome‐associated mutations in KV7.1/KCNE1 by the endocannabinoid N‐arachidonoyl‐L‐serine (ARA‐S)

British Journal of Pharmacology, Volume 182, Issue 13, Page 2861-2877, July 2025.
Abstract Background and Purpose Congenital long QT syndrome (LQTS) involves genetic mutations affecting ion channels, leading to a prolonged QT interval and increased risk of potentially lethal ventricular arrhythmias. Mutations in the genes encoding KV7.1/KCNE1 are the most frequent, with channel loss‐of‐function contributing to LQTS.
Irene Hiniesto‐Iñigo, Akshay Sridhar, Julien Louradour, Alicia De la Cruz, Siri Lundholm, Amaia Jauregi‐Miguel, Federica Giannetti, Luca Sala, Katja E. Odening, H. Peter Larsson, Nina E. Ottosson, Sara I. Liin   +11 more
wiley   +1 more source