Results 11 to 20 of about 72,190 (244)
Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Long QT syndrome in a neonate [PDF]
, 2015 Congenital long QT syndrome (cLQTS) is a channelopathy characterized by ventricular repolarization disturbances. The clinical presentation varies from an asymptomatic patient to a patient with recurrent syncopes, seizures, and even sudden death.
Morales Rodríguez, Idelma Berenise +3 more
core +1 more source
Meta-analysis of T peak –T end and T peak –T end /QT ratio for risk stratification in congenital long QT syndrome [PDF]
, 2018 Background and objectives: Congenital long QT syndrome (LQTS) predisposes affected individuals to ventricular tachycardia/fibrillation (VF/VF), potentially resulting in sudden cardiac death.
Baranchuk, Adrian M. +12 more
core +1 more source
Pediatria i Medycyna Rodzinna, 2014 Resting electrocardiogram is a basic diagnostic tool used to identify myocardial diseases caused by a genetic defect of ion channels that results in bioelectric instability of cardiomyocytes and the risk of a complex induction of life-threatening ...
Zbigniew Krenc
doaj +1 more source
Prevalencia de patrones electrocardiográficos asociados a muerte súbita en la población española de 40 años o más. Resultados del estudio OFRECE [PDF]
, 2017 [Abstract] Introduction and objectives. Some electrocardiographic patterns are associated with an increased risk of sudden cardiac death due to ventricular arrhythmias. There is no information on the prevalence of these patterns in the general population
Alonso Martín, Joaquín Jesús +11 more
core +3 more sources
Outcome by Sex in Patients With Long QT Syndrome With an Implantable Cardioverter Defibrillator
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background Sex differences in outcome have been reported in patients with congenital long QT syndrome. We aimed to report on the incidence of time‐dependent life‐threatening events in male and female patients with long QT syndrome with an implantable ...
Arwa Younis +11 more
doaj +1 more source
The QT Intervals in Infancy and Time for Infantile ECG Screening for Long QT Syndrome [PDF]
, 2011 Background: Electrocardiographic and molecular studies have clarified an association between sudden infant death syndrome (SIDS) and long QT syndrome (LQTS), and few data are available for the QT interval in infancy from birth to 1 year of age ...
Yoshinaga, Masao +13 more
core +2 more sources
Long QT interval in Turner syndrome--a high prevalence of LQTS gene mutations. [PDF]
PLoS ONE, 2013 QT-interval prolongation of unknown aetiology is common in Turner syndrome. This study set out to explore the presence of known long QT mutations in Turner syndrome and to examine the corrected QT-interval (QTc) over time and relate the findings to the ...
Christian Trolle +6 more
doaj +1 more source
Stem Cell Research, 2022 Long QT syndrome is one of the most common hereditary arrhythmias in clinic. Mutations in AKAP9 gene can lead to long QT syndrome type 11 (LQT11). In this study, a human induced pluripotent stem cell line ZZUSAHi004-A from a 3-year-old male patient with ...
Tongbin Ding +3 more
doaj +1 more source