Results 31 to 40 of about 72,610 (277)
Long QT interval in Turner syndrome--a high prevalence of LQTS gene mutations. [PDF]
PLoS ONE, 2013 QT-interval prolongation of unknown aetiology is common in Turner syndrome. This study set out to explore the presence of known long QT mutations in Turner syndrome and to examine the corrected QT-interval (QTc) over time and relate the findings to the ...
Christian Trolle +6 more
doaj +1 more source
Stem Cell Research, 2022 Long QT syndrome is one of the most common hereditary arrhythmias in clinic. Mutations in AKAP9 gene can lead to long QT syndrome type 11 (LQT11). In this study, a human induced pluripotent stem cell line ZZUSAHi004-A from a 3-year-old male patient with ...
Tongbin Ding +3 more
doaj +1 more source
GENETIC ASPECTS OF CONGENITAL LONG QT SYNDROME
Рациональная фармакотерапия в кардиологии, 2015 The main symptoms and clinical types of long QT syndrome are described. Molecular genetic diagnostics and updated approaches to the management of patients with long QT syndrome arepresented.
A. A. Chernova +2 more
doaj +3 more sources
Integration of genetics into a systems model of electrocardiographic traits using humanCVD BeadChip [PDF]
, 2012 <p>Background—Electrocardiographic traits are important, substantially heritable determinants of risk of arrhythmias and sudden cardiac death.</p> <p>Methods and Results—In this study, 3 population-based cohorts (n=10 526) genotyped ...
Adeniran, I. +24 more
core +1 more source
Mechanisms, Risk Factors, and Management of Acquired Long QT Syndrome: A Comprehensive Review
The Scientific World Journal, 2012 Long QT syndrome is characterized by prolongation of the corrected QT (QTc) interval on the surface electrocardiogram and is associated with precipitation of torsade de pointes (TdP), a polymorphic ventricular tachycardia that may cause sudden death ...
Eleftherios M. Kallergis +4 more
doaj +1 more source
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018 Long QT syndrome (LQTS) is a potentially life-threatening canalopathy, accompanied by prolonged QT interval on a 12-channel ECG, syncopal conditions and a high risk for sudden cardiac death due to the development of torsade de pointes (TdP ...
Kalatsei L. V., Snezhitskiy V. A.
doaj +1 more source
Shortening of the Short Refractory Periods in Short QT Syndrome. [PDF]
, 2017 BACKGROUND: Diagnosis of short QT syndrome (SQTS) remains difficult in case of borderline QT values as often found in normal populations. Whether some shortening of refractory periods (RP) may help in differentiating SQTS from normal subjects is unknown.
Cardin, C +10 more
core +3 more sources
Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018 Long QT syndrome (LQTS) is a potentially life-threatening channelopathy, accompanied by a prolonged QT interval on a 12-channel ECG, syncopal conditions and a high risk of sudden cardiac death due to the development of torsade de pointes (TdP ...
Kalatsei L. V., Snezhitskiy V. A.
doaj +1 more source
Site-Directed Mutagenesis and Site-Specific Binding Analysis of Calmodulin (CaM) [PDF]
, 2017 Calcium signaling is a major regulatory system in cells and a crucial part of cell biology. An important element in the decoding of intracellular calcium concentration into downstream processes is the ubiquitous and highly conserved calcium binding ...
Dokic, Yelena
core +1 more source
Transient Long QT Development in a Patient with Takotsubo Cardiomyopathy
Journal of Cardiovascular Emergencies, 2016 QT interval prolongation on the electrocardiogram is considered a precursory sign for imminent, potentially lethal ventricular arrhythmias. Beside the inherited condition of long QT syndrome, numerous drugs, certain electrolyte disturbances and early ...
Czuriga Dániel +10 more
doaj +1 more source