Results 41 to 50 of about 7,350,665 (262)

Prevalence of Long QT Syndrome in Children with Congenital Sensory-Neural Deafness

Journal of Ardabil University of Medical Sciences, 2021
Background & objectives: Long QT syndrome (LQTS), congenital or acquired disorder, is characterized by a prolonged QT interval associated with syncope attacks and sudden death.
Ahmad Jamei Khosroshahi, Mahmoud Samadi, Shamsi Ghaffari, Akbar Molaei, Fatemeh Chakari   +4 more
doaj  

Electrophysiology of the long qt syndromes [PDF]

Clinical Cardiology, 1990
The long QT syndromes are a collection of disorders, both acquired and congenital, in which episodes of syncope or presyncope occur secondary to a specific ventrticular tachycardia, «torsade de pointes», which arises in the setting of prolongation of ventricular repolarization as manifested by a prolonged QT interval on the surface electrocardiogram ...
N J, Linker, D E, Ward
openaire   +2 more sources

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor, Stefano Comai, Gianfranco Pasut, Franco Folli, Marco Gentilucci, Negar Gharavi, Sofia Raitsin, Thuy Van Nguyen, Marco Pappagallo, Andrea Mattarei, Paolo L. Manfredi, Sara De Martin   +11 more
wiley   +1 more source

Treatement methodes for Long QT syndrome

Journal of Education, Health and Sport, 2018
Long QT syndrome (LQTS) is a potentially fatal cardiac disorder caused by channelopathies. Such arrhythmia is often life threatening and might cause sudden cardiac death. There are many reasons of LQTS especially: specific medications and/or electrolytes
Erwin Ciechański, Magda Ciechańska, Krystian Ciechański, Jarosław Szponar   +3 more
doaj   +3 more sources

Selective acquired long QT syndrome (saLQTS) upon risperidone treatment

BMC Psychiatry, 2012
Background Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of the potassium channel.
Lazarczyk Maciej, Bhuiyan Zahir A, Perrin Nicolas, Giannakopoulos Panteleimon   +3 more
doaj   +1 more source

A phenomap of TTR amyloidosis to aid diagnostic screening

ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.
Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos, Theodoros Tsampras, George Lazaros, Konstantinos Tsioufis, Charalambos Vlachopoulos   +4 more
wiley   +1 more source

Exploring the impact of a KCNH2 missense variant on Long QT syndrome: insights into a novel gender-selective, incomplete penetrance inheritance mode

Frontiers in Genetics
BackgroundLong QT syndrome (LQTS) is an inherited malignant arrhythmia syndrome that poses a risk of sudden death. Variants in the Potassium Voltage-Gated Channel Subfamily H Member 2 (KCNH2) gene are known to cause Long QT syndrome through an autosomal ...
Peng Chen, Peng Chen, Zainul Zampawala, Hong Wang, Luyun Wang   +4 more
doaj   +1 more source

Vomiting, electrolyte disturbance, and medications; the perfect storm for acquired long QT syndrome and cardiac arrest: a case report

Journal of Medical Case Reports, 2022
Background Acquired long QT syndrome is an important and preventable cause of cardiac arrest. Certain medications and electrolyte disturbance are common contributors, and often coexist. In this case, we report five contributors to cardiac arrest.
K. D. Tiver, D. Dharmaprani, J. X. Quah, A. Lahiri, K. E. Waddell-Smith, A. N. Ganesan   +5 more
doaj   +1 more source

Case Report: Expanding the Phenotypic Spectrum of Timothy Syndrome Type 1: A Sporadic Case With a de novo CACNA1C Pathogenic Variant and Segmental Ileal Dilatation

Frontiers in Pediatrics, 2021
Background: Long QT syndactyly syndrome (long QT syndrome type 8), also known as Timothy Syndrome (TS) was first described in 1994 with still <50 case reported in the literature.
Ahmed A. Nugud, Nermeen Mahmoud ELkholy, Awad Alkarim Omar, Abid Qazi, Christos Tzivinikos, Christos Tzivinikos, Nidheesh Chencheri, Sabina Khan, Muhammad Eyad Ba'Ath, Muhammad Eyad Ba'Ath   +9 more
doaj   +1 more source

Genetics of Long QT Syndrome [PDF]

Methodist DeBakey Cardiovascular Journal, 2014
Long QT syndrome (LQTS) is a potentially life-threatening cardiac arrhythmia characterized by delayed myocardial repolarization that produces QT prolongation and increased risk for torsades des pointes (TdP)-triggered syncope, seizures, and sudden cardiac death (SCD) in an otherwise healthy young individual with a structurally normal heart.
David J, Tester, Michael J, Ackerman
openaire   +2 more sources