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Annals of Noninvasive Electrocardiology, 1998 Major progress has taken place, and at a very rapid pace, in the understanding of the congenital long QT syndrome (LQTS). This has been the direct consequence of the identification of several of the genes responsible for LQTS and of the studies that have followed, at both basic and clinical levels.
Silvia G. Priori, Peter J. Schwartz
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Trends in Cardiovascular Medicine, 1992 The familial long-QT syndrome (LQTS) is an infrequently occurring disorder in which affected family members have QT prolongation on the ECG, often associated with recurrent syncope and fatal ventricular arrhythmias. Autosomal recessive and autosomal dominant modes of inheritance were suggested by the pattern of occurrence of this disorder in the first ...
Arthur J. Moss, Jennifer L. Robinson
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Hepatology, EarlyView., 2022 Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou +13 more
wiley +1 more source
Praxis, 2010 #### Case scenario A 19 year old female student consulted her general practitioner about two recent episodes of syncope, both of which occurred while playing hockey. Her team mates reported that she collapsed suddenly with little warning, recovering rapidly within 30 seconds without confusion.
M. A. Perkin +2 more
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Hepatology, EarlyView., 2022 Natural history of liver disease in a large international cohort of children with Alagille syndrome: Results from the GALA study. Abstract Background and Aims Alagille syndrome (ALGS) is a multisystem disorder, characterized by cholestasis. Existing outcome data are largely derived from tertiary centers, and real‐world data are lacking.
Shannon M. Vandriel +93 more
wiley +1 more source
Drug-induced Fatal Arrhythmias: Acquired long QT and Brugada Syndromes [PDF]
, 2017 Since the early 1990s, the concept of primary “inherited” arrhythmia syndromes or ion channelopathies has evolved rapidly as a result of revolutionary progresses made in molecular genetics.
Ai, Tomohiko +3 more
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Long QT Syndrome and Pregnancy [PDF]
Journal of the American College of Cardiology, 2007 This study was designed to investigate the clinical course of women with long QT syndrome (LQTS) throughout their potential childbearing years.Only limited data exist regarding the risks associated with pregnancy in women with LQTS.The risk of experiencing an adverse cardiac event, including syncope, aborted cardiac arrest, and sudden death, during and
Seth R +17 more
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Circulation, 2020 Supplemental Digital Content is available in the text. Background: Long QT syndrome (LQTS) is a rare genetic disorder and a major preventable cause of sudden cardiac death in the young.
N. Lahrouchi +105 more
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Meta-analysis of T peak –T end and T peak –T end /QT ratio for risk stratification in congenital long QT syndrome [PDF]
, 2018 Background and objectives: Congenital long QT syndrome (LQTS) predisposes affected individuals to ventricular tachycardia/fibrillation (VF/VF), potentially resulting in sudden cardiac death.
Baranchuk, Adrian M. +12 more
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QT correction using Bazett’s formula remains preferable in long QT syndrome type 1 and 2
Annals of Noninvasive Electrocardiology, 2020 The heart rate (HR) corrected QT interval (QTc) is crucial for diagnosis and risk stratification in the long QT syndrome (LQTS). Although its use has been questioned in some contexts, Bazett's formula has been applied in most diagnostic and prognostic ...
P. Dahlberg +4 more
semanticscholar +1 more source