Results 31 to 40 of about 46,897 (193)

Update on long QT syndrome [PDF]

open access: yesJournal of Cardiovascular Electrophysiology, 2019
AbstractLong QT syndrome (LQTS) is an inherited disorder characterized by a prolonged QT interval in the 12‐lead electrocardiogram and increased risk of malignant arrhythmias in patients with a structurally normal heart. Since its first description in the 1950s, advances in molecular genetics have greatly improved our understanding of the cause and ...
Víctor Neira   +3 more
openaire   +4 more sources

LONG QT SYNDROME. PART 1

open access: yesŽurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2018
Long QT syndrome (LQTS) is a potentially life-threatening channelopathy, accompanied by a prolonged QT interval on a 12-channel ECG, syncopal conditions and a high risk of sudden cardiac death due to the development of torsade de pointes (TdP ...
Kalatsei L. V., Snezhitskiy V. A.
doaj   +1 more source

Long QT syndrome – Bench to bedside

open access: yesHeart Rhythm O2, 2021
Long QT syndrome (LQTS) is a cardiovascular disorder characterized by an abnormality in cardiac repolarization leading to a prolonged QT interval and T-wave irregularities on the surface electrocardiogram. It is commonly associated with syncope, seizures,
Daniela Ponce-Balbuena, PhD   +1 more
doaj   +1 more source

Genetics update: monogenetics, polygene disorders and the quest for modifying genes [PDF]

open access: yes, 2018
The genetic channelopathies are a broad collection of diseases. Many ion channel genes demonstrate wide phenotypic pleiotropy, but nonetheless concerted efforts have been made to characterise genotype-phenotype relationships.
Symonds, Joseph D., Zuberi, Sameer M.
core   +1 more source

Transient Long QT Development in a Patient with Takotsubo Cardiomyopathy

open access: yesJournal of Cardiovascular Emergencies, 2016
QT interval prolongation on the electrocardiogram is considered a precursory sign for imminent, potentially lethal ventricular arrhythmias. Beside the inherited condition of long QT syndrome, numerous drugs, certain electrolyte disturbances and early ...
Czuriga Dániel   +10 more
doaj   +1 more source

A study of early afterdepolarizations in a model for human ventricular tissue [PDF]

open access: yes, 2014
Sudden cardiac death is often caused by cardiac arrhythmias. Recently, special attention has been given to a certain arrhythmogenic condition, the long-QT syndrome, which occurs as a result of genetic mutations or drug toxicity. The underlying mechanisms
Kazbanov, Ivan   +5 more
core   +3 more sources

A common cardiac sodium channel variant associated with sudden infant death in African Americans, SCN5A S1103Y. [PDF]

open access: yes, 2006
Thousands die each year from sudden infant death syndrome (SIDS). Neither the cause nor basis for varied prevalence in different populations is understood.
Bowers, Peter N   +8 more
core   +2 more sources

Long QT in stunned myocardium: unrecognised cause of acquired long QT syndrome

open access: yesJournal of Medical Science, 2014
Long QT syndrome (LQTS) is a heart disorder characterized by a prolongation of the QT interval on ECG and a predisposition to ventricular tachyarrhythmias, which may lead to syncope, cardiac arrest or sudden cardiac death. This condition may be inherited
Jerzy Sacha
doaj   +1 more source

Resuscitation of sudden cardiac death caused by acute epileptic seizures: A case report

open access: yesJournal of Acute Disease, 2016
Symptomatic long QT syndrome in pediatric patients is a life-threatening condition. Sometimes, this pathology can be misdiagnosed and erroneously managed as generalized epilepsy due to similar clinical manifestations.
Dana-Oliviana Geavlete   +7 more
doaj   +1 more source

The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model

open access: yes, 2004
In this numerical study, we investigate the role of intrinsic heterogeneities of cardiac tissue due to M cells in the generation and maintenance of reentrant excitations using the detailed Luo-Rudy dynamic model. This model has been extended to include a
Cherry E. M.   +3 more
core   +1 more source

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