Results 31 to 40 of about 269,335 (318)

Long-QT-Syndrom

Praxis, 2010
#### Case scenario A 19 year old female student consulted her general practitioner about two recent episodes of syncope, both of which occurred while playing hockey. Her team mates reported that she collapsed suddenly with little warning, recovering rapidly within 30 seconds without confusion.
M. A. Perkin, J. R. Skinner, D. J. Abrams   +2 more
openaire   +5 more sources

Transethnic Genome-Wide Association Study Provides Insights in the Genetic Architecture and Heritability of Long QT Syndrome

Circulation, 2020
Supplemental Digital Content is available in the text. Background: Long QT syndrome (LQTS) is a rare genetic disorder and a major preventable cause of sudden cardiac death in the young.
N. Lahrouchi, R. Tadros, L. Crotti, Y. Mizusawa, P. Postema, L. Beekman, R. Walsh, K. Hasegawa, J. Barc, Mark Ernsting, Kari L. Turkowski, A. Mazzanti, B. Beckmann, K. Shimamoto, Ulla-Britt Diamant, Y. Wijeyeratne, Yu Kucho, T. Robyns, T. Ishikawa, E. Arbelo, Michael Christiansen, A. Winbo, R. Jabbari, S. Lubitz, J. Steinfurt, B. Rudic, B. Loeys, M. Shoemaker, P. Weeke, R. Pfeiffer, B. Davies, A. Andorin, N. Hofman, F. Dagradi, M. Pedrazzini, D. Tester, J. Bos, G. Sarquella-Brugada, Ó. Campuzano, P. Platonov, B. Stallmeyer, S. Zumhagen, E. Nannenberg, J. Veldink, Leonard H van den Berg, A. Al-Chalabi, C. Shaw, P. Shaw, K. Morrison, P. M. Andersen, M. Müller-Nurasyid, D. Cusi, C. Barlassina, P. Galan, M. Lathrop, M. Munter, T. Werge, M. Ribasés, T. Aung, C. Khor, M. Ozaki, P. Lichtner, T. Meitinger, J. P. van Tintelen, Y. Hoedemaekers, I. Denjoy, A. Leenhardt, C. Napolitano, W. Shimizu, J. Schott, J. Gourraud, T. Makiyama, S. Ohno, H. Itoh, A. Krahn, Charles Antzelevitch, D. Roden, J. Saenen, M. Borggrefe, K. Odening, P. Ellinor, J. Tfelt-Hansen, J. Skinner, Maarten P. van den Berg, M. Olesen, J. Brugada, Ramon Brugada, N. Makita, J. Breckpot, M. Yoshinaga, E. Behr, A. Rydberg, T. Aiba, S. Kääb, S. Priori, P. Guicheney, H. Tan, C. Newton‐Cheh, M. Ackerman, P. Schwartz, E. Schulze-Bahr, V. Probst, M. Horie, A. Wilde, M. Tanck, C. Bezzina   +105 more
semanticscholar   +1 more source

Drug-induced Fatal Arrhythmias: Acquired long QT and Brugada Syndromes [PDF]

, 2017
Since the early 1990s, the concept of primary “inherited” arrhythmia syndromes or ion channelopathies has evolved rapidly as a result of revolutionary progresses made in molecular genetics.
Ai, Tomohiko, Horie, Minoru, Itoh, Hideki, Turker, Isik   +3 more
core   +1 more source

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization. [PDF]

, 2013
The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate the presence of the potentially ...
Abecasis, GR, Ackerman, MJ, Adamkova, V, Alonso, A, Arking, DE, Arnar, DO, Asselbergs, FW, Bader, JS, Barc, J, Bardai, A, Beckmann, BM, Behr, ER, Bezzina, CR, Bis, JC, Bobbo, M, Boyer, LA, Bradford, Y, Brandimarto, J, Brion, M, Brown, M, Campbell, H, Cappola, TP, CARe Consortium, Carella, M, Carracedo, A, Caulfield, MJ, Chakravarti, A, Chatel, S, COGENT Consortium, Crotti, L, Cummings, SR, D'Adamo, AP, Dalageorgou, C, Daly, MJ, DCCT/EDIC, de Bakker, PI, de Boer, RA, del Greco M, F, den Hoed, M, Denny, JC, Dominiczak, AF, Dörr, M, Ehret, G, Eijgelsheim, M, Eisele, L, El Mokhtari, NE, Ellinghaus, D, eMERGE Consortium, Emilsson, V, Erbel, R, Evans, DS, Felix, SB, Ferrucci, L, Franco, OH, Franke, A, Franke, L, Frey, N, Fuchsberger, C, Gasparini, P, Ghidoni, A, Gieger, C, Giudicessi, JR, Greiser, KH, Griffin, M, Gudbjartsson, DF, Gudnason, V, Gustafsson, S, Haerting, J, Hamilton, RM, Harris, TB, Hayward, C, Heckbert, SR, Hicks, AA, Hingorani, AD, Hoffmann, P, Hofman, A, Hofman, N, HRGEN Consortium, Huang, H, Hubacek, JA, Hólm, H, Ingelsson, E, Insolia, R, Iorio, A, Isaacs, A, Jamshidi, Y, Johnson, AD, Jula, A, Jöckel, KH, Kao, WH, Kedenko, L, Kellis, M, Kiechl, S, Kivimaki, M, Kluttig, A, Knoflach, M, Kolcic, I, Kontula, KK, Koopmann, TT, Kors, JA, Krijthe, BP, Kronenberg, F, Kumar, RD, Kumari, M, Kyndt, F, Kähönen, M, Kälsch, H, Kääb, S, Lage, K, Lahtinen, AM, Lakatta, EG, Lamina, C, Larson, MG, Launer, LJ, Lee, WK, Lehtimäki, TJ, Lind, L, Liu, Y, Loos, RJ, Lundby, A, Lyytikäinen, LP, Macfarlane, PW, Margulies, K, Marjamaa, A, Markus, MR, Martens, E, Mateo Leach, I, Medeiros-Domingo, A, Meitinger, T, Meyer Zu Schwabedissen, H, Mononen, N, Moravec, CE, Morley, M, Morris, RW, Mulas, A, Munroe, PB, Mühleisen, TW, Müller-Nurasyid, M, Nalls, MA, Naluai, ÅT, Navarro, P, Navis, G, Newhouse, SJ, Newton-Cheh, C, Nicolaides, AN, Nolte, IM, Noseworthy, PA, Nyberg, F, Nöthen, MM, O'Connell, JR, O'Donnell, CJ, Oikarinen, L, Olsen, JV, Oostra, BA, Orrú, M, Padmanabhan, S, Panayiotou, AG, Parsa, A, Paterson, AD, Paulweber, B, Perola, M, Perz, S, Peters, A, Pfeufer, A, Plump, AS, Polašek, O, Porthan, K, Post, WS, Pramstaller, PP, Probst, V, Prucha, H, Psaty, BM, Pulit, SL, Raitakari, OT, Raychaudhuri, S, Ritchie, MD, Roden, DM, Rossin, EJ, Rotter, JI, Rudan, I, Salomaa, V, Samani, NJ, Sanna, S, Scherer, SW, Schlessinger, D, Schott, JJ, Schwartz, PJ, Shuldiner, AR, Sinagra, G, Sinner, MF, Siscovick, DS, Slowikowski, K, Smith, AV, Smith, JG, Snieder, H, Sotoodehnia, N, Spector, TD, Stefansson, K, Strait, JB, Stricker, BH, Strohmer, B, Sundström, J, Syvänen, AC, Tanaka, T, Tarasov, KV, Tester, DJ, Thelle, DS, Thorsteinsdottir, U, Torres, M, Uda, M, Uitterlinden, AG, Ulivi, S, van den Berg, MP, van der Harst, P, van der Vleuten, PA, van Duijn, CM, van Veldhuisen, DJ, Viikari, JS, Völker, U, Waggott, D, Waldenberger, M, Wang, X, Watt, GC, Werdan, K, Whincup, PH, Wild, SH, Wilde, AA, Willeit, J, Wilson, JF, Witteman, JC, Wright, AF, Yin, X, Zelante, L, Zuvich, RL, Ärnlöv, J   +234 more
core   +3 more sources

Postpartum QT Prolongation in a Long QT Syndrome Type 1 Patient. [PDF]

Ann Noninvasive Electrocardiol
We present the case of an LQT1 patient with a previous cardiac event during the postpartum period. Performance of electrocardiograms and Estradiol as well as Progesterone levels revealed prolonged QT intervals postpartum correlating to declining sex hormone levels elevate the risk for arrhythmic events in this period.
Wiedenmann LC, Ehrlich JR, Goldenberg I.
europepmc   +2 more sources

QT correction using Bazett’s formula remains preferable in long QT syndrome type 1 and 2

Annals of Noninvasive Electrocardiology, 2020
The heart rate (HR) corrected QT interval (QTc) is crucial for diagnosis and risk stratification in the long QT syndrome (LQTS). Although its use has been questioned in some contexts, Bazett's formula has been applied in most diagnostic and prognostic ...
P. Dahlberg, Ulla-Britt Diamant, T. Gilljam, A. Rydberg, L. Bergfeldt   +4 more
semanticscholar   +1 more source

Long QT interval in resting electrocardiogram– and what next? Sports cardiologist’s point ofview Part 2. From provocative tests to prevention of cardiac events

Pediatria i Medycyna Rodzinna, 2014
Resting electrocardiogram is a basic diagnostic tool used to identify myocardial diseases caused by a genetic defect of ion channels that results in bioelectric instability of cardiomyocytes and the risk of a complex induction of life-threatening ...
Zbigniew Krenc
doaj   +1 more source

Patient-specific induced pluripotent stem-cell models for long-QT syndrome.

New England Journal of Medicine, 2010
BACKGROUND Long-QT syndromes are heritable diseases associated with prolongation of the QT interval on an electrocardiogram and a high risk of sudden cardiac death due to ventricular tachyarrhythmia.
A. Moretti, M. Bellin, A. Welling, C. Jung, J. Lam, Lorenz Bott-Flügel, Tatjana Dorn, A. Goedel, C. Höhnke, F. Hofmann, M. Seyfarth, D. Sinnecker, A. Schömig, K. Laugwitz   +13 more
semanticscholar   +1 more source

Outcome by Sex in Patients With Long QT Syndrome With an Implantable Cardioverter Defibrillator

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Sex differences in outcome have been reported in patients with congenital long QT syndrome. We aimed to report on the incidence of time‐dependent life‐threatening events in male and female patients with long QT syndrome with an implantable ...
Arwa Younis, Mehmet K. Aktas, Spencer Rosero, Valentina Kutyifa, Bronislava Polonsky, Scott McNitt, Nona Sotoodehnia, Peter Kudenchuk, Thomas D. Rea, Dan E. Arking, Ilan Goldenberg, Wojciech Zareba   +11 more
doaj   +1 more source

Long QT interval in Turner syndrome--a high prevalence of LQTS gene mutations. [PDF]

PLoS ONE, 2013
QT-interval prolongation of unknown aetiology is common in Turner syndrome. This study set out to explore the presence of known long QT mutations in Turner syndrome and to examine the corrected QT-interval (QTc) over time and relate the findings to the ...
Christian Trolle, Kristian H Mortensen, Lisbeth N Pedersen, Agnethe Berglund, Henrik K Jensen, Niels H Andersen, Claus H Gravholt   +6 more
doaj   +1 more source