Background Miniature inverted-repeat transposable elements (MITEs) and long terminal repeat (LTR) retrotransposons are ubiquitous in plants genomes, and highly important in their evolution and diversity.
Yan Liu +8 more
doaj +1 more source
Interaction of the v-rel protein with an NF-kappa B DNA binding site [PDF]
The avian reticuloendotheliosis virus T contains within its genome the oncogene rel. The expression of this gene is responsible for the induction of lymphoid tumors in birds.
Doemer, M. +5 more
core +2 more sources
Tau Protein Hyperphosphorylation and Aggregation in Alzheimer’s Disease and Other Tauopathies, and Possible Neuroprotective Strategies [PDF]
Acknowledgments This work was supported by The Croatian Science Foundation grant No. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Babić Leko, Mirjana +11 more
core +3 more sources
Background In eukaryotes, long terminal repeat (LTR) retrotransposons such as Copia, BEL and Gypsy integrate their DNA copies into the host genome using a particular type of DDE transposase called integrase (INT).
Bao Weidong +2 more
doaj +1 more source
Long terminal repeat retrotransposons (LTR-RTs) make up a considerable portion of plant genomes. New insertions of these active LTR-RTs modify gene structures and functions and play an important role in genome evolution.
Hyunjin Koo +6 more
doaj +1 more source
Subtelomeric CTCF and cohesin binding site organization using improved subtelomere assemblies and a novel annotation pipeline [PDF]
Mapping genome-wide data to human subtelomeres has been problematic due to the incomplete assembly and challenges of low-copy repetitive DNA elements. Here, we provide updated human subtelomere sequence assemblies that were extended by filling telomere ...
Courtney, Laura +13 more
core +2 more sources
Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses. [PDF]
Mesenchymal tumor subpopulations secrete pro-tumorigenic cytokines and promote treatment resistance1-4. This phenomenon has been implicated in chemorefractory small cell lung cancer and resistance to targeted therapies5-8, but remains incompletely ...
A Marusyk +75 more
core +1 more source
Helquat dyes targeting G-quadruplexes as a new class of anti-HIV-1 inhibitors
The secondary structure of nucleic acids containing quartets of guanines, termed G-quadruplexes, is known to regulate the transcription of many genes.
Marcela Pávová +7 more
doaj +1 more source
Terminal-repeat retrotransposons with GAG domain in plant genomes : a new testimony on the complex world of transposable elements [PDF]
A novel structure of nonautonomous long terminal repeat (LTR) retrotransposons called terminal repeat with GAG domain (TR-GAG) has been described in plants, both in monocotyledonous, dicotyledonous and basal angiosperm genomes.
Akaffou, S. +11 more
core +5 more sources
Major G-Quadruplex Form of HIV-1 LTR Reveals a (3 + 1) Folding Topology Containing a Stem-Loop [PDF]
Nucleic acids can form noncanonical four-stranded structures called G-quadruplexes. G-quadruplex-forming sequences are found in several genomes including human and viruses.
Anh Tuân Phan +6 more
core +2 more sources

