Results 31 to 40 of about 330,554 (315)
Long terminal repeat retrotransposons of Mus musculus [PDF]
Genome Biology, 2004 Long terminal repeat (LTR) retrotransposons make up a large fraction of the typical mammalian genome. They comprise about 8% of the human genome and approximately 10% of the mouse genome. On account of their abundance, LTR retrotransposons are believed to hold major significance for genome structure and function. Recent advances in genome sequencing of
McCarthy, Eugene M., McDonald, John F.
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BMC Genomics, 2021 Background Long Terminal Repeat retrotransposons (LTR retrotransposons) are mobile genetic elements composed of a few genes between terminal repeats and, in some cases, can comprise over half of a genome’s content.
Oluchi Aroh, Kenneth M. Halanych
doaj +1 more source
Reliance of Host-Encoded Regulators of Retromobility on Ty1 Promoter Activity or Architecture
Frontiers in Molecular Biosciences, 2022 The Ty1 retrotransposon family is maintained in a functional but dormant state by its host, Saccharomyces cerevisiae. Several hundred RHF and RTT genes encoding co-factors and restrictors of Ty1 retromobility, respectively, have been identified.
Alicia C. Salinero +8 more
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Inverted repeats in the long-terminal repeats of the wheat retrotransposon Wis 2-1A. [PDF]
Molecular Biology and Evolution, 1992 The wheat insertion sequence Wis 2-1A possesses all the structural features characteristic of retrotransposons. Its long-terminal repeats (LTRs) are unusually long (1,755 bp) compared with those of other retrotransposons. Sequence analysis revealed that they differ from each other by only six point mutations.
Lucas, Helene +3 more
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Association of Endogenous Retroviruses and Long Terminal Repeats with Human Disorders [PDF]
Frontiers in Oncology, 2013 Since the human genome sequences became available in 2001, our knowledge about the human transposable elements which comprise ∼40% of the total nucleotides has been expanding. Non-long terminal repeat (non-LTR) retrotransposons are actively transposing in the present-day human genome, and have been found to cause ∼100 identified clinical cases of ...
Iyoko Katoh, Shun-ichi Kurata
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NFAT5 regulates HIV-1 in primary monocytes via a highly conserved long terminal repeat site. [PDF]
PLoS Pathogens, 2006 To replicate, HIV-1 capitalizes on endogenous cellular activation pathways resulting in recruitment of key host transcription factors to its viral enhancer. RNA interference has been a powerful tool for blocking key checkpoints in HIV-1 entry into cells.
Shahin Ranjbar +7 more
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Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Human immunodeficiency virus 1 (HIV-1) infection causes a life-long disease, due to the ability of the virus to integrate into the host genome and establish latent infection.
M. Taura, E. Song, Y. Ho, A. Iwasaki
semanticscholar +1 more source
Evidence for the recent horizontal transfer of long terminal repeat retrotransposon [PDF]
Proceedings of the National Academy of Sciences, 1999 The evolutionary dynamics existing between transposable elements (TEs) and their host genomes have been likened to an “arms race.” The selfish drive of TEs to replicate, in turn, elicits the evolution of host-mediated regulatory mechanisms aimed at repressing transpositional activity.
John F. McDonald +2 more
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Genomic Evolution of the Long Terminal Repeat Retrotransposons in Hemiascomycetous Yeasts [PDF]
Genome Research, 2002 We identified putative long terminal repeat- (LTR) retrotransposon sequences among the 50,000 random sequence tags (RSTs) obtained by the Génolevures project from genomic libraries of 13 Hemiascomycetes species. In most cases additional sequencing enabled us to assemble the whole sequences of these retrotransposons.
Horst Feldmann +4 more
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Nucleic Acids Research, 2016 The long terminal repeat (LTR) of the proviral human immunodeficiency virus (HIV)-1 genome is integral to virus transcription and host cell infection. The guanine-rich U3 region within the LTR promoter, previously shown to form G-quadruplex structures ...
Beatrice De Nicola +7 more
semanticscholar +1 more source