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The NOVA Center for Global Health coordinated the +Longevity Think Tank, recognizing the importance of fostering reflection within Portuguese society on the enhanced role that vaccines can play as a factor in prevention and in promoting active and healthy aging.
George, Francisco +7 more
+15 more sources
Most of the western world has seen a steady increase in the average lifetime of its inhabitants over the past century. Although the past trends suggest that further changes in mortality rates are to be expected, considerable uncertainty exists regarding the future development of mortality. This type of uncertainty is referred to as longevity risk. This
De Waegenaere, A.M.B. +2 more
openaire +3 more sources
Background Modern medicine is rapidly moving towards a data-driven paradigm based on comprehensive multimodal health assessments. Integrated analysis of data from different modalities has the potential of uncovering novel biomarkers and disease ...
Ilan Shomorony +19 more
doaj +1 more source
The fact that people are on average living healthier, longer lives than previously has the potential to be positive for the economy, offsetting the negative economic effects of an ageing society. A longevity economy will see a shift in the mix of sectors in the economy, with both health and education expanding further and new financial products arising.
openaire +3 more sources
As the demographic transition enters a new stage of a longevity transition, focus needs to extend beyond an ageing society towards a longevity society. An ageing society focuses on changes in the age structure of the population, whereas a longevity society seeks to exploit the advantages of longer lives through changes in how we age.
openaire +3 more sources
Utilization of defined microbial communities enables effective evaluation of meta-genomic assemblies
Background Metagenomics is the study of the microbial genomes isolated from communities found on our bodies or in our environment. By correctly determining the relation between human health and the human associated microbial communities, novel mechanisms
William W. Greenwald +7 more
doaj +1 more source
A set of common buccal CpGs that predict epigenetic age and associate with lifespan-regulating genes
Summary: Epigenetic aging clocks are computational models that use DNA methylation sites to predict age. Since cheek swabs are non-invasive and painless, collecting DNA from buccal tissue is highly desirable.
Adiv A. Johnson +3 more
doaj +1 more source
This issue of PLoS Biology includes the first in a series of "historical" book reviews.
openaire +4 more sources
Declining metabolic function with aging is a conserved phenotype across many species. While aging-associated changes in metabolic status have been investigated rigorously in humans, less is known about metabolic aging in dogs.
Brennen McKenzie +17 more
doaj +1 more source
Translational immune and metabolic markers of aging in dogs
Dogs serve as a promising aging model due to their genetic diversity, condensed lifespan, and shared living environment with humans. Alterations in the immune and metabolic parameters are hallmarks of aging in humans, but few studies have investigated ...
James E. McMahon +9 more
doaj +1 more source

