Results 21 to 30 of about 362,508 (212)
Cell Reports, 2012 Controversy has recently arisen over the role of sirtuins in metazoan aging. In this issue of Cell Reports, Banerjee et al. demonstrate that Drosophila Sir2 is necessary for life span extension in response to dietary restriction and that its overexpression in the fat body increases the life span.
David Sinclair, Eric Verdin
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Longevity Genes: From Primitive Organisms to Humans [PDF]
, 2002 A variety of lines of evidence indicate that aging and longevity are subject to genetic regulation, but until fairly recently the identity of these genes was unknown. This has changed dramatically over the last ten years.
Huber Warner
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Efficient versus inefficient hedging strategies in the presence of financial and longevity (value at) risk [PDF]
, 2013 This paper provides a closed-form Value-at-Risk (VaR) for the net exposure of an annuity provider, taking into account both mortality and interest-rate risk, on both assets and liabilities.
Regis, Luca, Luciano, Elisa
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Beyond longevity: healthy longevity [PDF]
The Lancet Healthy Longevity, 2021 Alain, Putot +3 more
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Aging, 2012 While the basic elements of telomere biology are very similar across many taxa [1], there is diversity among species, and among tissues, in telomere dynamics. Not surprisingly, given that species differ in many other relevant aspects of their biology, including the pattern of activity of the telomere-restoring enzyme telomerase simple comparisons of ...
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eLife, 2020 Worms with increased levels of the epigenetic mark H3K9me2 have a longer lifespan that can be passed down to future generations.
Felicity Emerson +2 more
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dna-seq/oakvar-longevity: Publishing data
, 2023 OakVar longevity ...
Malvina Pushkova +4 more
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Acta Microbiologica et Immunologica Hungarica, 2018 The role of immune system is to protect the organism from the not built-in program-like alterations inside and against the agents penetrating from outside (bacteria, viruses, and protozoa). These functions were developed and formed during the evolution.
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Thermosensation and longevity [PDF]
Journal of Comparative Physiology A, 2015 Temperature has profound effects on behavior and aging in both poikilotherms and homeotherms. To thrive under the ever fluctuating environmental temperatures, animals have evolved sophisticated mechanisms to sense and adapt to temperature changes. Animals sense temperature through various molecular thermosensors, such as thermosensitive transient ...
Rui, Xiao, Jianfeng, Liu, X Z Shawn, Xu
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