Results 91 to 100 of about 2,058,289 (307)

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Onda Longitudinal

, 2016
O vídeo mostra uma animação onde é possível visualizar uma onda longitudinal, sendo que, as partículas estão se movendo na mesma direção de propagação das ondas.
Pelletier, Yves
core   +1 more source

Transition Into Adolescence: A Longitudinal Study, 1974-1979

This longitudinal study evaluates the transition from childhood into early and middle adolescence and how it is affected by the type of school a child attends, onset of puberty, and gender.
Simmons, Roberta G., Blyth, Dale A.
core   +2 more sources

From imputation to impact

, 2018
The topics included in this issue range from the imputation of missing data in longitudinal surveys to demonstrating that their results make a difference in the public arena – both challenges to our research field the world over.
Joshi, Heather
core   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Plasma lipids connecting olfaction with cognition and physical function

Scientific Reports
Olfactory deficit is an early sign of neurodegenerative diseases, such as Alzheimer’s disease (AD), and is related to age-related cognitive and physical function decline. However, underlying biological processes are not fully understood.
Erin E. Greig, Susan M. Resnick, Luigi Ferrucci, Qu Tian   +3 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Knee extension rate of torque development and peak torque: associations with lower extremity function

Journal of Cachexia, Sarcopenia and Muscle, 2018
Background With aging, the ability to generate muscle force decreases, contributing to declines in physical functions such as walking. While most studies assess muscle force by peak torque, the rate of torque development (RTD) reflects a dynamic ...
Yusuke Osawa, Stephanie A. Studenski, Luigi Ferrucci   +2 more
doaj   +1 more source