Results 71 to 80 of about 2,501,169 (303)

Volume 9, No 2

, 2018
Full issue of Longitudinal and Life Course Studies journal, Volume 9, No ...
Jeal, Sarah
core   +1 more source

Longitudinal Joint Specifications and Performance [PDF]

, 2012
Deterioration of longitudinal joints is widely recognized as one of the major factors contributing to failure of asphalt pavements. Finding ways to improve the durability of longitudinal joints will lead to improved service lives and lower life cycle ...
Olek, Jan, McDaniel, Rebecca S., Shah, Ayesha   +2 more
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Describing the geographical linkage between the UK Millennium Cohort Study and crime incidents in England and Wales

International Journal of Population Data Science
Background Enhancing longitudinal cohort studies by linking routine external data to them is increasingly used to evaluate how local environments impact participants' outcomes (e.g.
Nicolas Libuy, Emla Fitzsimons, David Church   +2 more
doaj   +1 more source

Haploidentical Hematopoietic Cell Transplantation for Infants With X‐Linked Severe Combined Immunodeficiency Using Post‐Transplant Cyclophosphamide

Pediatric Blood &Cancer, EarlyView.
Shuhei Takahashi, Akito Kawachi, Dan Tomomasa, Eri Watanabe, Yuji Fujita, Yuya Sato, Masahiro Sekiguchi, Kentaro Watanabe, Moe Hidaka, Akihiro Hoshino, Takahiro Kamiya, Masatoshi Takagi, Hirokazu Kanegane, Motohiro Kato   +13 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Onda Longitudinal

, 2016
O vídeo mostra uma animação onde é possível visualizar uma onda longitudinal, sendo que, as partículas estão se movendo na mesma direção de propagação das ondas.
Pelletier, Yves
core   +1 more source

The effect of fludrocortisone and midodrine on ambulatory blood pressure biomarkers and symptoms of syncope

Blood Pressure
Introduction Fludrocortisone and midodrine are frequently used to raise blood pressure (BP) in patients with vasovagal syncope (VVS)/low BP phenotype and orthostatic hypotension (OH), despite limited supporting evidence.
Kate Doyle, Ciara P. Rice, Rose Anne Kenny, Robert Briggs, Amanda H. Lavan   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source