Results 81 to 90 of about 2,058,289 (307)

The validation of short eating disorder, body dysmorphia, and Weight Bias Internalisation Scales among UK adults

Journal of Eating Disorders
Background When collecting data from human participants, it is often important to minimise the length of questionnaire-based measures. This makes it possible to ensure that the data collection is as engaging as possible, while it also reduces response ...
Dorottya Lantos, Darío Moreno-Agostino, Lasana T. Harris, George Ploubidis, Lucy Haselden, Emla Fitzsimons   +5 more
doaj   +1 more source

The Effect of Targeted Incentives on Response Rates and Representativeness: Evidence From the Next Steps Age 32 Survey

Survey Research Methods
This paper analyses the effect on response rate and non-response bias of tailoring the level of monetary incentives offered to participants in a longitudinal study, depending on sample members’ response propensity. Specifically, we test whether offering
Alessandra Gaia, Matt Brown, Tugba Adali, Stella Fleetwood, Christy Lai   +4 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

The effect of fludrocortisone and midodrine on ambulatory blood pressure biomarkers and symptoms of syncope

Blood Pressure
Introduction Fludrocortisone and midodrine are frequently used to raise blood pressure (BP) in patients with vasovagal syncope (VVS)/low BP phenotype and orthostatic hypotension (OH), despite limited supporting evidence.
Kate Doyle, Ciara P. Rice, Rose Anne Kenny, Robert Briggs, Amanda H. Lavan   +4 more
doaj   +1 more source

Lifelong childlessness in England and Wales Evidence from the ONS Longitudinal Study

, 2010
Previous research on childlessness suggests that childless women differ from those with children mainly in terms of their attitudes and values. In the literature, mixed evidence exists regarding how distinctive childless women are in terms of their socio-
Portanti, Martina, Whitworth, Simon Matthew   +1 more
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Sensitivity analysis within multiple imputation framework using delta-adjustment: Application to Longitudinal Study of Australian Children

, 2018
Multiple imputation (MI) is a powerful statistical method for handling missing data. Standard implementations of MI are valid under the unverifiable assumption of missing at random (MAR), which is often implausible in practice.
Lee, Katherine J., Hayati Rezvan, Panteha, Simpson, Julie A.   +2 more
core   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Changes in knee extension peak torque and body composition and their relationship with change in gait speed

Journal of Cachexia, Sarcopenia and Muscle, 2019
Background Slow gait speed is a powerful predictor of disability in activities of daily living and mortality. Muscle strength and body composition change over time, but their changes differ by sex.
Yusuke Osawa, Nancy Chiles Shaffer, Michelle D. Shardell, Stephanie A. Studenski, Luigi Ferrucci   +4 more
doaj   +1 more source