Results 51 to 60 of about 2,501,169 (303)

Linking death registration and survey data: Procedures and cohort profile for The Irish Longitudinal Study on Ageing [version 1; peer review: 2 approved, 1 approved with reservations]

HRB Open Research, 2020
Background: Research on mortality at the population level has been severely restricted by an absence of linked death registration and survey data in Ireland.
Mark Ward, Peter May, Robert Briggs, Triona McNicholas, Charles Normand, Rose Anne Kenny, Anne Nolan   +6 more
doaj   +1 more source

Using linked Hospital Episode Statistics data to aid the handling of non-response and restore sample representativeness in the 1958 National Child Development Study.

International Journal of Population Data Science, 2022
Objectives There is growing interest in whether linked administrative data have the potential to aid analyses subject to missing data in cohort studies.
Nasir Rajah, Lisa Calderwood, Bianca De Stavola, Katie Harron, George Ploubidis, Richard Silverwood   +5 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

A data driven approach to address missing data in the 1970 British birth cohort

BMC Medical Research Methodology
Background Missing data may induce bias when analysing longitudinal population surveys. We aimed to tackle this problem in the 1970 British Cohort Study (BCS70). Methods We utilised a data-driven approach to address missing data issues in BCS70.
Michail Katsoulis, Martina K. Narayanan, Brian Dodgeon, George B. Ploubidis, Richard J. Silverwood   +4 more
doaj   +1 more source

Getting better all the time? Selective attrition and compositional changes in longitudinal and life-course studies [PDF]

, 2017
Longitudinal surveys are valuable tools for investigating health and social outcomes across the life course. In such studies, selective mortality leads to changes in the social composition of the sample, but little is known about how selective survey ...
Lennartsson, Carin, Fors, Stefan,, Fors, S,, Kelfve, Susanne,, Lennartsson, C,, Fors, Stefan, Lennartsson, Carin,, Kelfve, Susanne, Kelfve, S,   +8 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Trail Making Test performance contributes to subjective judgment of visual efficiency in older adults [PDF]

PeerJ, 2015
Introduction. The determinant factors that influence self-reported quality of vision have yet to be fully elucidated. This study evaluated a range of contextual information, established psychophysical tests, and in particular, a series of cognitive tests
Annalisa Setti, James Loughman, George M. Savva, RoseAnne Kenny   +3 more
doaj   +2 more sources

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Life-course socioeconomic position and health in older adulthood: a causal mediation analysis in the 1958 British Birth Cohort

The Lancet Regional Health. Europe
Summary: Background: Childhood socioeconomic position (SEP) influences later health, but how inequalities persist into early older age and operate through adult SEP remains unclear. Quantifying these pathways is important for identifying opportunities to
Yiling Guo, Alina Pelikh, George B. Ploubidis, Alissa Goodman   +3 more
doaj   +1 more source