Results 201 to 210 of about 94,291 (298)

CNC–PNIPAM Drug Delivery System Improves Endometrial Receptivity via Natural Killer Cell Immune Tolerance in Endometriosis

open access: yesAdvanced NanoBiomed Research, EarlyView.
An injectable CNC–PNIPAM hydrogel is developed for intrauterine co‐delivery of levonorgestrel and botropase. This platform reprograms uterine natural killer cells toward an immune–tolerant phenotype and enhances endometrial receptivity marker expression. The results demonstrate a promising strategy to counteract endometriosis–associated infertility and
Zhou Liang   +9 more
wiley   +1 more source

Giant Magnetostriction in Ferrimagnetic SmFe5As3

open access: yesAngewandte Chemie International Edition, EarlyView.
SmFe5As3 is a newly discovered ferrimagnetic material that displays peculiar volumetric effects as a function of temperature. As a result of two magnetic sublattices—one with d$d$‐electrons of Fe and another with f$f$‐electrons of Sm—single crystals of SmFe5As3 show negative (blue), positive (pink), and zero (beige) thermal expansion along the [010 ...
Oksana Karychort   +21 more
wiley   +1 more source

Lipid Pocket Binders Impose Allosteric Changes of Protein Dynamics Around the Active Site of the Protein Kinase p38α

open access: yesAngewandte Chemie International Edition, EarlyView.
Used in search of novel allosteric sites in the serine/threonine kinase p38α, NMR spectroscopy reveals a dynamic coupling between the catalytic and lipid pockets. The findings uncover a motional interdependence that links distant regions of the enzyme, highlighting the lipid pocket as a promising site for allosteric intervention.
Sara Medina Gómez   +4 more
wiley   +1 more source

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